"Indapamide" - kauoha no ka hoʻohana

Indapamide "- he lāʻau pili ana i ka pae ana o thiazide diuretics i ka antihypertensive hopena. Medicine "Indapamide" i hōʻike mai no ka hoʻohana 'ana ma ke alo o ka hypertension.

Pharmacological hana "Indapamide" lāʻau

Alakaʻi memo i ka pharmacological waiwai o ka lāʻau ua pili i ka thiazide diuretics. Waiū i ka lāʻau 'hiki o selectively ka paleʻana i ka "' ūlōlohi" kalipuna Kanal ka poʻea pau i ka elasticity o ka arterial pā, a ma laila mea i ka ho'ēmiʻana i loko o huinaʻike ākea vascular e kū'ē'ē mai.

"Indapamide" 'aʻole i hoololi ae carbohydrate pūnao, i mea oluolu no ka hoʻomanawanui iki mai me mimikō, a aole i pili i ka lehulehu o lipids ma ka wai koko. Papa "Indapamide" kōkua emi hypertrophy o ka ventricle hema, desensitize vascular pā i ka norepinephrine a me ka angiotensin II, stimulates ka hoʻololi kemikala o prostaglandin E2, ho'ēmi i kā ka? Iecaianoaaiiie o ka oxygen radicals. IeAUPIIe, IAa IO he 5-7 lā lapaʻau me antihypertensive hookoia ua hoikeia mai, hoomau ana me ka hookahi mahele lāʻau ma ka lā.

Pharmacokinetics "Indapamide" lāʻau

Alakaʻi ai ia mau moʻolelo i ka lāʻau wehewehe aku ma ka kiʻekiʻe bioavailability (93%), a omo i loko o ka gastrointestinal'āpana. I ka uku o ke omo ololi aiʻai ana. I ka lani kiekie loa lehulehu o ka lāʻau i loko o ke koko ua hana i loko o kekahi paha, elua no hora mahope iho o ka lawe ana i ka lāʻau i loko o ka nui o 2,5 mg. Ka lāʻau 'Ua metabolized ma ke akepaʻa. 60% -80% o ka mea ka ia auoiaea ma nā puʻupaʻa i loko o ka palapala o metabolites, ka hola 20% - ma ka liʻiliʻi. Ka lāʻau 'ʻAʻohe hiki cumulating.

Nāʻikepili "Indapamide"

Instruction prescribes i ka lāʻau no ka hakumakuma ke koko. Nō hoʻi, i ka lāʻau ua pono no ka poe me chronically leaking naau ole.

Contraindications

"Indapamide" ua contraindicated ma:

- mahuahua pā lonoaʻili i ka ia, a me nā nā mea loaʻa o ka sulfonamide pae,

- anuria,

- hypokalemia,

- loa hepatic aʻaʻa puʻuwai insufficiency,

- i ka wā o ka lactation,

- huʻi pathology o cerebral holo,

- hāpai keiki,

- i ka makahiki o ka 18 (aie i ka pouli)

- i ka wā hoʻokahi aaieieno? O pharmaceuticals hoʻoulu i ka wā QT.

Kaiapuni lawelawe i ka lāʻau i loko o ke alo o ka gout a me ka mimikō decompensation.

Dosing a dosing ai ' "Indapamide"

Alakaʻi i ke heluhelu lawe huaale i loko,ʻaʻole wai. 2,5 mg (kela la i keia mahele lāʻau) ua maikaʻi loa hoʻohana 'ia i loko o ke kakahiaka, a me ka auwina la. A hiki i ka 1-2 mahina ala o ka lāʻau lapaʻau i ole lawe mai i ka i makemake pākōlea kanawai, ua i waiho i ka mahele lāʻau e hoomahuahua aie i ka māhuahua pilikia o kaʻaoʻao loa. Ma keia hihia, i ka lāʻau Inc o hypertension noaia Pono e kākau i kekahi antihypertensive Agena i mea ole he diuretic. I ka hana maikaʻi mau antihypertensive lāʻau mahele lāʻau "Indapamide" koe ka ia.

overdose

Overdose symptoms i hoikeia mai ma ka nawaliwali, kue o gastrointestinal hana, nausea, ka luaʻi, loli a me ka electrolyte haunaele. Ma kekahi hihia ia i hoʻomaka ai overdose o naehana hanu kaumaha a me ka excessive hakumakuma o ke koko,. Ma nā mea maʻi me ka cirrhosis o ke akepaʻa ke hana hepatic coma.

I Ina o ka overdose e halihaliia oia iwaho? Iaea e normalize i ka wai-electrolyte koena: He gastric lavage a me symptomatic Inc.

AaOIeIOUIeXAOAaIN

Hoʻokāʻoi aʻe ana i ka hopena o ka 'ē aʻe ai' no kiʻekiʻe ke koko. Mai hui pu iho la me ka lapaʻauʻia i loaʻa ka likiuma, vincamine, kaliyvyvodyaschie diuretics.

ʻaoʻao waiwai o ka lapaʻauʻia "Indapamide"

Like me, like ma ka hihia o ka overdose. Paha naau pāpana haunaele ma muli o ke poho o ka potasiuma. Nō hoʻi,ʻaoʻao 'ole e hana ana ka nawaliwali, he oi emi ka puʻe ka wā e ku ana, nausea, abdominalʻeha, diarrhea, convulsions, allergic reactions. Ma pohihihi keia hoopii, e mahuahua gout, cramps.