Ka lāʻau "Ofloxacin": hoʻomanawanui, e hoike. Na Ke Kumu no ka hoʻohana ana i ka antibiotic "Ofloxacin"

E hoomakaukau ai "Ofloxacin" lākiō i nā mea maʻi i ka hapanui 'oluʻolu, ho i ka antimicrobial agena, mai ka pae ana o fluoroquinolones ka laulā pae o ka ha awina. Ka lāʻau e loli ai i ka DNA gyrase - mea koʻohune apana nahaha, ka hoʻolako 'supercoiling, a no ia mea, i ke kumupaʻa o koʻohune DNA (i ka hopena o ka destabilization o ka DNA ili aku ai make).

pharmacodynamics

O ia hoʻi, "Ofloxacin" - he antibiotic mana me ka pili ana i ka microorganisms e paka Hoʻokolohua-lactamase, e like me ka hoʻokēʻai-ulu atypical mycobacteria. I ka laau lapaau i ikepili koʻikoʻi, loa Gram-io koʻohune, me microorganisms mea e hoʻopale ai i methicillin a me nā antibiotics. Streptococci, enterococci, a me ka Mycobacterium tuberculosis e wehewehe aku ia e lolelua ka susceptibility i ka lāʻau "Ofloxacin". Reviews o ka lapaau hōʻike i loko o ka iapaau ana o ka anaerobic nā mea palahēhē kena ae la ia e peptostreptokokki, peptokokki a me nā anaerobes, i ka lāʻau 'Ua pinepine ineffective.

Pharmacokinetics

Ma ka loaʻa 'ka medicament i loko o ka omo ka piha (95 pakeneka) a me ka hoʻokēʻai. Bioavailability - oi ma mua o 96 pakeneka. Pili i ka wai koko nā polokina - 25 pakeneka. Ma hope o kekahi i mau hola ma hope o moʻolelo hooponopono ana o ka mea kiekie loa lehulehu i hiki aku kona. He mahele lāʻau-e kaukaʻi: ka hookahi ana o elua haneri, eha a eono haneri milligrams o ka lāʻau lehulehu i pakahi 2,5, 5 a 6,9 ug / ml.

Food hokii mea e loli i ke omo o kaʻaoʻao o ka slowdown, akā,ʻaʻohe nui hopena ma bioavailability. E hoomakaukau ai "Ofloxacin" - he antibiotic me he nui ka leo o ka o ka makana (hoʻokahi haneri galani), no laila, i ka lawelawe hoomalolo Ua kokoke piha huina komo iloko o ka 'elele i loko o na keena. Ka mea kiekie loa nā hoʻohui like i loko o nā nā'aʻaʻa, kino fluids a me nā loko: ma na keena (alveolar macrophages, leukocytes), palupalu'aʻaʻa,ʻili, iwi, naehana nenoaiu, pelvic a me ka abdominal lua, tuha, prostatic secretions, mimi, bile. Ke medicament punawai komo iloko o ka placental a me ke koko-lolo lâhui, ua pee mai ka umauma i ka waiū, a me ka cerebrospinal loli komo ma ka ole-wela ai a me ka wela ai lolo membranes (14 a hiki i 60 pakeneka).

About 5 pakeneka o ka lāʻau ua metabolized ma ke akepaʻa, e hana dimetilofloksatsina a me N-'okesaside o ofloxacin. Nānā 'ole o ka mahele lāʻau hapa-ola i waena o eha a me ka hapalua i ehiku hola. Auaiaea kŰlń lāʻau i loko o ka nui o 75-90 pakeneka o nā puʻupaʻa, ma ka nui o 4 pakeneka - i loko o ka bile. Emi iho malalo o 20 pakeneka o ka extrarenalʻae. Ma hope o ka hookahi mahele lāʻau o ka elua haneri milligrams o ka Agena o detectable i loko o ka mimi no 20-24 hola. Ma ka hihia o hepatic aʻaʻa puʻuwai excretion paha e ka meheu o. I ka dialysis ua wehe 'ia e 10 a hiki i 30 pakeneka o ka lapaʻauʻia.

nāʻikepili no ka

Ma infectious a me ka hoʻoʻino mai, kena ae la ia e likeʻole microorganisms, hōʻike noi medicament "Ofloxacin". Reviews Ua hai aku i ka mea, ua maikai loa ia no ka naehana'āpana nā mea palahēhē (pneumonia, bronchitis), luna naehana'āpana (otitis Media, sinusitis, laryngitis, pharyngitis). Hāʻawi aku lāʻau i palupalu'aʻaʻa lesions, ami, iwi,ʻili, biliary'āpana, urinary'āpana (urethritis, cystitis), hakuʻala (pyelonephritis), abdominal lua, genitalia (orchitis, colpitis, epididymitis), pelvic nā loko (salpingitis, prostatitis, cervicitis, endometritis, oophoritis, kiko'î).

I ka hoʻokō lāʻau no ka ureaplasmosis, chlamydia, gonorrhea. E hoʻohana i ia no ka Kāohiʻana o nā mea palahēhē i loko o nā mea maʻi me kāna hana o ka'ōnaehana paleʻea kūlana haʻahaʻa (me ka neutropenia).

I ka laʻau heluna palapala. 'ole

Ke kala o ka medicament mea i loko o ka palapala o ke kapa komo iā ia keʻokeʻo a kokoke keʻokeʻo Auana-lole komoʻuʻuku nona papa biconvex a shape. Ke kea mahele kekahi 'mau papa, kekahi o ka i mai he yellowish tint. ʻeleu ke keʻena hana like ofloxacin. Hoʻokahi papa i loko o ka ahakanaka o ka 200 a me 400 mg. Nā hana nā mea hoʻohui i primelloza (croscarmellose paʻakai), microcrystalline kelulose, Aerosil (colloidal silikone'okikene lua), ka silica i titania, povidone, hydroxypropyl methylcellulose (hypromellose), talc, makanekiuma stearate, polyethylene glycol 4000 (macrogol). A nui ia Morohiha o ka lāʻau "Ofloxacin" - kumukuai. Papa i loaʻa ka 200 mg oʻeleu waiwai i ka awelika o 16-20 rubles no 10 mau apana, a me ka poe i pihaʻi me 400 milligrams ofloxacin, loaʻa nō ma kahi o 50-55 rubles no 10 apana.

"Ofloxacin" laau lapaau. Na Ke Kumu no ka hoʻohana

E inu maloko o na papa mua ma hope o kaʻai paha. Ka mea, pono e ale a pau, me ka e kamaiʻilio ana, a ua inu i ka wai i loko o ka poe liilii, mea. Ka laʻau heluna E e koho pākahi ke kaumaha ma muli o ka oolea o ka maʻi, i ka IIeEeAIEUAA o ka maʻiʻaʻai, ke hoʻomanawanui i ka mau ana, hakuʻala hana, ake, a me nā koʻohune pā lonoaʻili.

E like me ka rula, o ka iapaau ana o "ofloxacin" ua i na la ehiku i na la he umi. Makua kela la i keia hoakakaʻai ana o ka elua haneri, eono haneri milligrams palua i ka lā. hiki e mahuahua ai ka mahele lāʻau i ewalu milligrams ma ka hihia o ka mea maʻiʻaʻai, a ina mea overweight i ka hoʻomanawanui. A mahele lāʻau o ka eha milligrams hiki e ia ma koke, kaʻoi loa i loko o ke kakahiaka.

Nā mea maʻi me kaʻoleʻaʻa puʻuwai kuleana pili i kekahi manawa, hiki ole lawe elua haneri hou ma mua o milligrams o ka lāʻau, i ka i kā mākou mahele lāʻau i kela la i hepatic hoʻopilikia - eha haneri milligrams. Ma hope o ka nalowale ana o symptoms a me normalization o ke ana wela, a hiki no elua a ekolu lā e hoʻomau Inc.

ʻaoʻao 'ole. e hoike

Aʻole a pau e hoomanawanui i ka lāʻau "Ofloxacin" pono tolerated. Reviews o kekahi kanaka i loko o ka 'ike i ka lāʻau kumu headache, nausea, ka luaʻi, diarrhea, tremors, numbness oʻaoʻao. Ma ka hapa o ka digestive'ōnaehana e hoʻomōhala like abdominal eha, gastralgia, bloating, cholestatic jaundice, anorexia, hyperbilirubinemia, pseudomembranous enterocolitis, a me ka ua'emi nenoaia - nele o ka neʻe, cramps,, pili nā moeʻuhane, psychotic reactions, manaʻo pīhoihoi, uunu nui, ka hilahila, phobias, hallucinations, kaumaha.

Eia hou kekahi, he mea i ka pilikia o ka 'aʻe' ana o ka Hawaii'ōnaehana (arthralgia, tendonitis, myalgias), makaukau no (hoao i kāna hana, 'ia nā pōpō hihio, lohe, kaulike, honi), vascular'ōnaehana a me ka naau (ka ho'ēmiʻana i loko o ke koko,, tachycardia), ka ili (dermatitis, kuhi hemorrhage, papular poʻe noʻonoʻoʻole), no hematopoiesis (thrombocytopenia, anaemia, leukopenia). Ma hope o ka loaa ana "Ofloxacin" lāʻau (hōʻike manaʻo hōʻoia i kēia), i loko o kekahi mau hihia eia kahi mea akaka itchy ili, bronchospasm, urticaria.

Contraindications

Loaa ana medicament i papaiaʻi intolerance ofloxacin a me nā fluoroquinolone nā mea loaʻa, ma ka hihia o ka deficiency o ka monakō koko-6-posapahate dehydrogenase, epilepsy, lesions o na tendons, hoemi kāʻili 'ana i paepae. Eia hou, e hiki ole lawe i ka lāʻau "Ofloxacin" hapai a me lactating wahine, na keiki ma lalo o ka makahiki o kaʻumikumamāwalu. Me ka manao e hoʻomākaukau ai ua hoakaka ia no ka circulatory kāna hana ma ka lolo, cerebral vascular atherosclerosis,ʻaʻa puʻuwai ole i ka maʻi CNS lesions ke aloha ano.

Medicament "Ofloxacin" ma ka ureaplasma. Reviews

Ke kumu nui mea mea i kanaka e olelo aku nei, e hoʻohana i ka hoonui - ia kona ola ai. E hoomanawanui i hōʻike i ka hopena o kekahi 'ma ke kolu a me ka ha o ka lā mua. Akā, he mea pono e ao aku ia oukou i keia 'aʻole i manaʻo i ka hoouka kaua o ka daimonio. A o ka poe e hoomanawanui i ka poe i pani i ka inu na papa, me ka hele ana ma ka piha papa, a laila, hou ua hoano e ureaplasmosis symptoms, no ka mea, o ka koʻohune i ole ua loa eliminated.

Cautions

I ka pneumonia hoonaukiuki ma pneumococcus, i ka lāʻau ineffective. No hoi, ka mea, ua i hōʻike no ka iapaau ana o ka huʻi tonsillitis. He pono e pau ana i ka lāʻau 'ina ma ke kāʻei kua o kona komo' ike i allergic naoh, ka CNS kāna hana, pseudomembranous colitis. Women anaʻano "Ofloxacin", ka mea, ua i paipai i ka hoʻohana tampons, no ka mea, ma keia hihia he mea ka māhuahua pilikia o ka ulu thrush.