Neuroblastoma i na keiki, 4 ke kahua. Kumu, symptoms, symptoms, prognosis. neuroblastoma lapaʻau o ke keiki

Neuroblastoma - he maʻi 'aʻai o ke aloha o ko mākou hopohopo nenoaiu. Ma ka hapanui o hoopii, i kēia maʻi ua 'akomi i loko o kahi mau keiki liilii. Manaʻoi hoʻokoe 'kona ka loaʻaʻana maoli ka hiki ole o ka piha ke ola. Mai na mea o keia 'atikala oe, e aʻo i ka walaʻauʻana kumu o ka maʻi, i symptoms ka mea, ua hele pū, i kahi kanaka ua koi' ia.

Kupaianaha ano o ka neuroblastoma i loko o ke keiki

Neuroblastoma - ka loa, he pono ole ʻeho mea he malignant külana. Ua hoike no ma kahi o 15% o nā mea a pau i hōʻike 'hihia o hikoko o ka neonatal wā a me ka noho' ana kamaliʻi i kakahiaka nui. Poe akamai i ke ano nui hōʻikeʻeho ma na keiki mai ana i elima makahiki, aka, aia no na hihia o ka maʻi i loko o adolescents 11, a he 15 makahiki. Me ka ulu a me ka ulu ana o ke keiki paha e maka i kēia insidious maʻi ua hoemiia kela makahiki.

ʻeho o neuroblasts, e like me ke kauka, ua hāʻawi me ka, heʻe piʻoloke ihola nā mea hiki. He oi loaʻano pākīkē, a prone i metastasis ma kekahi hapa o ke kino. Loa pinepine e ae mai ka hope o ka iwi a me ka lymphatic kahua. I kekahi manawa kauka paa neuroblast ulu foci lākou papa me ka hope kahua o ka hikoko. I mua metastasizes, laila, ke wehe 'ia kona ulu, a hoʻomaka e regress. Malignancies o kekahi 'ano i wehewehe aku ma ia symptoms.

Brain neuroblastoma i loko o nā keiki i mua hoʻokolokoloʻia e kānakaʻepekema, mai Hawaii, Rudolfom Virhovym i loko o ka makahiki 1865. Ke kauka i kapaʻeho "glioma." A mau makahiki ma hope o ka 'Amelika nä känaka' epekema Dzheyms Rayt kaupaona i nā loko o hou au mamuli neoplasm, a wehewehe i ka au mamuli o ka kaʻina o kona ho okumu.

Ka hooulu kahua o ka hoʻonaʻauao o ka neuroblastoma

Like kekahi 'ē Ka maʻi' aʻai hikoko, neuroblastoma i loko o na keiki hele ma kekahi mau kahua o ka hoʻonaʻauao o? Acaeoey oʻike mau, e like me ka ho'ākāka 'e leie akuʻoe e hāʻawi i ka hoʻokō hana:

• Ke kahua 1 ua wehewehe aku ma ke alo o resectable hikoko nona ka nui, aole ia i oi aku mamua o 5 knm, a me ka wa e kaawale aku o lymph wahi metastases.
• I Wa 2a. Hoike o IIeEeAIEUIeXAIIUE hikoko, ka hapanui o ka i mea malalo iho i ka hoopau ana.
• Kai 2B. Lymph wahi metastases ana unilaterally.
• Ka anu u 3. wehewehe aku ma keʻanoʻeluaʻaoʻao hikoko.
• KaʻAnuʻu Hana 4 (A-B). Neoplasm ulu, he mea metastasis i ka iwi lolo, ake a me ka lymph aka wahi.

Mākou E hoi, e hoomanao i ka hope kahua o ka ulu neuroblastoma i loko o nā keiki. KaʻAnuʻu Hana 4 i kekahi,ʻaʻole auaneʻiʻoukou liluwelo 'ano neoplasias hoomaha, mai ke prognosis maikai, a ina' eleu lapaʻau haawi i ke kiʻekiʻe ola kōmi.

I ka papa kuhikuhiE kumu o kaʻeho ulu

Neuroblastoma, e like me nā 'ano o ka maʻi' aʻai, e hoʻomōhala ana i ma luna o ke kāʻei kua o aaiaoe mutations i loko o ka meaola. Currently, poe akamai i hiki ole ke olelo i ka mea e haawi ala i kēia mau hoʻololi. Ua Ua ea ae ka hana i ke kūlana hoʻokani ma ka ai-kapaia carcinogenic aʻe, 'o ia hoʻi, Nine Inch a me ka pāhawewe. Ke kūpono mutation keena hoʻomaka e proliferate, ho okumu i kaʻeho. Malignant neoplasm wehewehe aku ma ka hiki e kaʻana i ka distinguishes ia mai benign.

Mutation o hoʻonāukiuki i ke kahua o ka neuroblastoma kupu i loko o ke au o fetal? Acaeoey a koke ma hope o ka hānau o ke keiki. Nolaila, loa nā mea maʻi - grudnichki. Ke kumu o kaʻeho hoʻomaka ma neuroblasts. Kēiaʻiliahi nā aʻalolo keena, a i hanaʻia i loko o ka fetus i kona intrauterine ulu. Ma ka maʻamau papa o ka hāpai keiki neuroblasts lawe i ka hana o nā aʻalolo olona, a me aeee i kuleana no ka ho okumu ana o ka adrenal glands.

ka hapanui o ia i ua hana i ka manawa o ka hanau ana o ke keiki. ʻiliahi keena pele nalo. A hiki i ka pathological kaʻina o nā neuroblasts i kēia huli i loko o kaʻeho. Ka wale maopopo o ka maʻi 'aʻai ololi - he aaiaoe predisposition. Eia naʻe, no ka pilikia o hereditary mai, aole ia i oi aku mamua o 2%.

Loa pinepine, kauka diagnose retroperitoneal neuroblastoma, he punahele kahi IIeEeAIEUAA - ka adrenal glands. Theoretically, kaʻeho e ala mai anywhere i loko o ke kino. Retroperitoneal neuroblastoma i na keiki ana i ka 50% o ka hoopii, 30% o nā mea maʻi hoʻomohalaʻeho nodules o nā aʻalolo ka lumbar aina, i ka i koe 20% koho no ka IIeEeAIEUAA o cervical a me ka thoracic.

Pehea e holo ai i kaʻeho?

Ma ka loiloi mua ke kahua o ka pathological kaʻina o nā hana i ho'ākāka 'symptoms mea i ka malamaia. No laila, i kaʻeho ua pinepine ike no nā maʻi i ho'ākāka 'ia i kēia makahiki pae.

Symptoms o neuroblastoma i loko o na keiki ana ke kaumaha ma muli o ka wahi o ka IIeEeAIEUAA hikoko, mau mea o metastatic hohola a me ka nui o vasoactive waiwai. Maʻamau, ka iniiaiieʻeho wahi mea i loko o ka retroperitoneal makahiki, nui kaʻoi loa i loko o ka adrenal glands. Ma pohihihi keia hoopii, ka mea, ua IIeEeAIEUIeXAIIUE ia ma ka ai paha i loko o ka mediastinum.

Pehea i neuroblastoma i loko o nā keiki? Symptoms o ka maʻi i ke kumu ma ke kala ana o hormones ma ka maʻi 'aʻai keena a hikoko mau puʻe ma kekahi' ole ka 'ē aʻe kino. I kekahi manawa, kona ulu e loli ai i ka functioning o ka naʻau liʻiliʻi, a bladder. Ma muli o ka mīkini'opihia ana o na moku i ke koko i loko o nā mea maʻi ia lŘlŘ scrotum, a malalo nuku edema.

Lepaʻano a bluish mau kiko ma kaʻili i kekahi symptoms o ka neuroblastoma i loko o nā keiki. Lākou helehelena Hōʻike komo i loko o ka pathological kaʻina hana o ka epidermal keena. Me ka anal o kaʻeho 'ana i loko o ka iwi ka lolo o ke keiki i nawaliwali, pinepine mai. Ma keia hihia, a he uuku ka eha ke 'ai pono i ka nui kahe ana ke koko.

Ka lōkahi o ka symptoms o neuroblastoma, nā mākua e nīnau aku i ke kauka. ka loaʻaʻana o ka maʻi 'aʻai ma kekahi kakahiaka nui ke kahua me ke hoola i kekahi keiki ka ola.

Retroperitoneal neuroblastoma

Neoplasm o neurogenic kumu o ka'aʻaʻa e ia lŘlŘ ma ka retroperitoneal makahiki, wehewehe aku ma ka ulu kokololio. Ma ka pōkole manawa, e komo i loko o ka spinal Canal, ho okumu i kekahi ao hana mau o kaʻeho, i hiki ke 'akomi i ka palpation.

Neuroblastoma o ka adrenal gland i loko o nā keiki initially, aole kekahi symptoms a ka mea hiki i ke kilakila nui, a hoʻomaka e paʻa e pili nā'aʻaʻa. He aha nō nā'ōuli o akakaʻeho?

1. Ke alo aku o ka anuanu ho okumu i loko o ka abdominal lua.
2. Haanou ana o ke kino a pau.
3. Discomfort a me kaʻeha ma ka lumbar māhele 'āina.
4. Weight me keia poho.
5. An hoomahuahua i ana wela.
6. Loli i loko o ke koko nā hoailona e hoike mai ana i ka anemia.
7. Numbness, lōlō o ka lalo lala.
8. Leʻa hoʻi i ka iaea ooieoeiiaeuiiai nā mea hiki o ka gastrointestinal'āpana a me urinary kahua.

Other IIeEeAIEUAA o neurogenic me Kinohi hikoko

Neuroblastoma posterior mediastinum i keiki ua pu ma kekahi pahi kaumaha poino, pilikia moni 'ia, he kāna hana o ka naehana ha awina. Ma kekahi mau hihia, i ka maʻiʻo ia i kekahi loli ma ke kinona o ka pahu.

Hikoko zaglazno makahiki i loa pohihihi, akā, eʻike hou aku no ia. O ke kumu ho i ka mea e pau ai ka hoailona o ka pathological kaʻina hiki i ka maka kapa ole. Neoplasm wehewehe aku ma ka helehelena o ka pouli kahi ma luna o ka maka, a nana e like me ka maʻamau loa. Kekahi symptom ua kuu iho neuroblastoma lihilihi. Ua uhi he unnaturally bulging a poʻopoʻo.

'ano apau loa neuroblastomas

Ma keia mau loea, maopopo neuroblastoma eha ano, kela mea keia mea o ka i mai i kekahi wahi, a IIeEeAIEUAA kiʻiona ano.

• Medulloblastoma. Neoplasm originates hohonu i loko o ka cerebellum, i mea no ke aha la ka mea hiki ole ke wehe ia eʻoki kino. Ke pathology Ua wehewehe aku ma ka kokololio metastasis. Ka mua symptoms o ka maʻi 'aʻai ikea incoordination.
• Retinoblastoma. Kēia malignancyʻeho mea e loli ai ka retina o ka maka i ka opiopio nā mea maʻi. I ka nele o ka lapaʻau hiki aku ai i ka nui ka makapo a me ka lolo metastases.
• Neyrofibrosarkoma. Kēiaʻeho ua IIeEeAIEUIeXAIIUE i loko o ka abdominal lua.
• Simpatoblastoma. Kēiaʻeho He malignant, i mea i kona "hale" Nāna e koho i ke aloha o ko mākou hopohopo'ōnaehana a me adrenal glands. Neoplasm i hanaʻia i loko o ka fetus i kona intrauterine ulu. Aie i ka mea kokololio mea ulu i loko o ka spinal kaula i ke loli ma ka nui simpatoblastomy i entails lōlō.

Pehea eʻike neuroblastoma?

Initially, ke kauka prescribes i kēiaʻike, 'Neuroblastoma' koko a me ka mimi ho'āʻo ma. I na keiki, na symptoms o keia maʻi i like i nā maʻi, a me nā keʻena hoʻokolohua ikea ai o liluwelo mea eliminates'ē aʻe hiki kumu. High holo 'awelika o ka catecholamine hormones i loko o ka mimi Hōʻike i ke alo o ka maʻi' aʻai.

E hoʻoholo i ka nui o kaʻeho, kona IIeEeAIEUAA opiopio nā mea maʻi i hoakakaia HI, ultrasound a me MRI. nui An iaoia mea PalekanaEND_LINK biopsy. I loko o kēia kaʻina hana, he hoʻomalu i ka pa maʻi 'aʻai keena no mahope keʻena hoʻokolohua ninaninau, histological Ka Ikepili.

Ma muli o ka hoao ana i nā hualoaʻa i ke kauka e hoʻomōhala ana i nā kaʻa mokulele o ka lapaʻau, ua hoakaka alakaʻi ma ka lapaau a me ke ala o ke ola o ka hoʻomanawanui.

Inc koho

Lapaʻau o neuroblastoma i loko o ke keiki ua ana kākou i loko o mau hoʻomalu oncology Oihana (himioterapevt, surgeon, radiologist). Ma hope o këia i nā 'ano o kaʻeho, e kauka ulu nā kaʻa mokulele o kona luku. Ua hilinaʻi nui ma luna o pehea kaʻeho mākou ke pane i na hana haliia mai la mawaho, a me ka kēla i ka manawa o ka hopeʻike.

Nui, hana maikaʻiʻole o ka neuroblastoma i loko o na keiki ka loaʻa o ka kēia kiʻina hana:

1. Chemotherapy. Kēia kaʻina hana komo ai i ka hoike o Anati-Ka maʻi 'aʻai ai' i ka pela 'ia manaʻo. Hoomakaukau detrimental ia ma luna o ka maʻi 'aʻai keena, pale kā lākou'ōlelo. Me ia loli ana i nā māhele o ke kino, i hiki aku ai i ka mea e like me kaʻaoʻao waiwai (lauoho poho, nausea, diarrhea). I ka laulā o ka Inc ua mahuahua ma kekahi mau manawa ma ka huipūʻana me ka transplantation o ka lolo.
2. ʻoki lāʻau lapaʻau lapaau komo ai i ka wehe 'ana o hikoko. Ma mua o ka hana ua noi chemotherapy. Ua apono 'oe e' ūlōlohi mai anaʻeho ka ulu a me ka pono regression o metastases. Admissibility ke hoʻokō 'ia kona pōpilikia' ana i hilinaʻi nui ma luna o ka wahi a me ka nui. A uukuʻeho kahi kokoke i ka spinalʻula, e 'uao loa risky.
3. Ka pāhawewe ke Inc i loko o kēia 'inikua hoʻomaʻamaʻa ua kākaʻikahi i hoʻohana. He increasingly i loko o nā makahiki auou caiaiaiʻoki kino me pono me ka pāhawewe mea e palekana a me ka hāpai i kekahi hoʻoweliweli 'ana i ke ola ana o ke keiki. Ka pāhawewe ke Inc ua paipai ikaika ma luna o ka hōʻike, ka wā he mea he haahaa ka hoʻokōʻana o nā ano o ka lapaau, ma ka hihia o unresectable neuroblastoma i loko o nā keiki.

A kūikawāʻai a me kaʻike, liilii, e hoomanawanui i ua ole i hōʻike. He nui na makua e ho'āʻo ana e hana me nā'ēheu kēia'ēheu o ka aoao o ke ola o Chad, hoʻomaʻa kānaʻai hoʻi. Ua Ua hoao ia kekahi o nā huahana a, oi kaʻoi loa, i ka waiwai iloko o loko o ia mau mea, hoonui i ke kino i ka pale aku ia lakou, a markedly inhibit i ka ulu ana o hikoko. Oia waiwai nā kiniki, hao, betaine, likeʻole nā wikamina. Ka mea, ua waiwai ma ka citrus hua, ui greens, carrots, kaʻuala.

I ka pomaikai o kekahi lapaau hilinaʻi nui ma luna o ka nui neuroblastoma i loko o nā keiki. Nā kumu o ka maʻi a me ke kahua o ka maʻi i mea nui. Noi'ano'ē epekema ma na kahua o ka hoʻonaʻauao kakahiaka o kaʻeho ho okumu haawi manaolana no ka piha daimonio. Naʻe, i kēia 'aʻole i höʻike aku i ka poe uuku a hoomanawanui i kauka kipa, a hele i ka hookolokolo ana ma ka mea e ole ka hiki recurrence.

Pahiki hope loaa ua i hoʻokoe 'ia ma ka lua o ka mua, aka i ka holomua ana a me ka chemotherapy.

Kekahi pilikia e ala aʻeʻoe i loko o nā kuʻina hope o keia pathology like neuroblastoma. Children 4 kahua o ka maʻi 'aʻai ua ana pu ma ka loaa ole ia Time]. Relapse mea hiki hope ana o kaʻeho, ma ke kāʻei kua o seemingly ke ola. ʻO kekahi hanauna o malignant ano ua ana i hanaʻia i loko o ka ia wahi ma kekahi manawa, ua. Ke kēla no keia anu u mea 20% ola no elima makahiki. Ma keia hihia, a pau hilinaʻi nui ma luna o ke aʻo o ka hoʻomalu, ai ka loaʻa nui o ka mea kupono 'inikua lako a pan.

Outlook

Ma hope mālama nui Inc oncology prognosis no ka hapanui nā mea maʻi e maikaʻi. Children me IIeEeAIEUIeXAIIUEʻeho kaʻina, kauka e olelo aku nei paha, e loaa like hikiwawe e loaa ana. Me ka pili ana i keia waeʻano o nā mea maʻi, i kaʻeho i nalo a hiki oleʻoki kino, akā, mālama nui 'inikua Inc ma keia hihia mea OAXA. Ma mua na keiki, ua hohola mai i kaʻeho, i ka manawa o ka piha hou ana, ua nui emi. A, i kaʻeho hiki recur.

Ke no o ka lapaau pinepine Radio he haumāna neuroblastoma i loko o nā keiki. Ei ma keia hihia mea ole ka loa maikaʻi. Kaʻeho e hōʻike hou ma hope o kekahi mau makahiki, a me ma hope holomua lapaau. Kēiaʻano o nā mea hoʻomaoe ma ka lapaau haawiia i like pōʻaoʻao ole. Ia mea ke kumu a pau nā mea maʻi ole, koe nae, ma hope o ka papa o ka Inc ua paipai 'ana a kauka ua mau malama.

kāohi ana

Kauka mai e haawi aku i kekahi manaʻo koi no ka pale i ka hooulu ana o ka malignant ano o kaʻeho, a me na kumu no kona ho okumu ka mea, no poorly maopopo, a me ke koe nae o ka manao hereditary predisposition. Inā kokoke hoahanau loa i ka hana i kēia insidiousʻike, i hāpai keiki hoʻolālā mea kupono i ka hele i ke kukakuka ana o doctor- geneticist. ka mea, hoʻoneʻe 'ia paha, e kōkua pale' ana i ka haunaele pili me ka hanau ana o kekahi keiki unhealthy.

Eia naʻe, 'aʻai ua manawa increasingly diagnosed ma opiopio e hoomanawanui i mea ole koe neuroblastoma i loko o nā keiki. Photo pathology hiki ke loaʻa ma ka hana kūikawā 'inikua pili puke. O kekahi 'ano o ka Kāohiʻana, kauka hiki ole kaumaha no ka unclear etiology pathology. I ka suggestive o keia maʻi i ka iniiaiie symptoms, ia mea nui, e imi 'inikua'ōlelo aʻo. Wale ma hope o hele ana ma o ka piha PalekanaEND_LINK loiloi 'ke hoʻoponopono i ke ano o ka hikoko, a, e hoʻoikaika i maikaʻi loa lapaʻau ka hoʻolālā. Ka mua akamai, e hoopaa i kaʻike, hope, i ka maikaʻi o ka manawa no ka piha ke ola. E hoʻokaʻaʻike ola!