"Quinidine": aʻo no ka hoʻohana 'ana, haku mele' ana, hōʻikeʻano a me ka hōʻike manaʻo

No ke aha la hana ua pono i ka mea paahana e like me "quinidine"? Na Ke Kumu no ka hoʻohana, kūʻai, a me nā hōʻike manaʻo i ka hookohu o ka lāʻau i hōʻike mai iā ia ma lalo nei. Oe e kekahi e ao i ka pharmacological waiwai ano o ka lāʻau, ina ka mea, o ka hanaʻaoʻao o ke ano, a ike ia he mea kekahi kapu no ka hana.

I ka haku mele 'ana, kinona, hōʻikeʻano

Ma ka palapala mea lāʻau lapaʻau poe e lāʻau "quinidine"? Na Ke Kumu no ka ho ohana i, pili i keia mea, o ia ka mea hiki ke kuai i loko o ka palapala o ka i lalo, a puni na papa. Ka mea, i ka hooloihi ae i keia, a ho film-kapa komo iā ia.

I ka papa kuhikuhiE 'Oponopono o keia lapaau mea quinidine sulufahate. Na Ke Kumu, huahana hōʻikeʻano 'aʻole e haawi aku i kekahi' ike ma luna o nā waiwai.

Pharmaceuticals mea lāʻau lapaʻau Products

He aha e na huaale "quinidine"? Na Ke Kumu no ka hoʻohana 'ana, hōʻikeʻano, ua hai aku hōʻike manaʻo i ia mea he laau no Class IA arrhythmia. He hiki ke 'ūlōlohi i ka amo ana o Ion ma Na auwai a hookeai aeea pā o cardiomyocytes, a emi i ka mämä holo kali depolarization a me ka hoomahuahua i ka lōʻihi like' ole o ka Loaʻaʻia 'ana a me ka refractory (ka hoʻokō) lōʻihi o ka manawa.

? Eaia o ka medicament attenuates myocardial excitability, 'aʻole hoʻi automaticity a door-conduction i loko o nā aka wahi, laulau lala aeie, atrial a me nā hale. Kekahi noonoo ano he vagolytic hopena hoike mai ai ia ka m-anticholinergic hookoia, ho'ēmi i kā ka ha awina (contractility) o ka naau Muscle a me ke kumu i ka ho'ēmiʻana i loko o ke koko,.

waiwai o ka lāʻau

He aha ka mea kupaianaha o ka lapaau like "quinidine"? Na Ke Kumu no ka hoʻohana memo i ka mea hiki i ka io inotropic hopena. Kēia ia lŘlŘ like me ka hopena o deceleration o ka maloko ikehu huli ana kaʻina hana i loko o mitochondria. Me ka pili ana i ka antiarrhythmic waiwai o ka lāʻau, ka mea e pili ana me ke alo o ka amide pūʻulu ma ka lātoma 'ole o ka hana waiwai.

E like me ka poe akamai, i kaʻai ana o keia medicament ua me ka nui loa hoemi excitation a me ka propagation māmā holo, a ua pili me ka waiū o ka mea hana lāʻau ke keʻena i ke kaʻina hana o ka depolarization.

Uhi ka m-cholinergic receptors, noʻonoʻo i ka lāʻau stimulates door-conduction. At pākōlea nā māhele e hōʻike hypotensive waiwai pili me ka hōʻemiʻana leoʻike ākea aa koko a me arteries, e like me ka io inotropic hopena.

Mākou hiki ole ke olelo i keia k mea hiki ke hōʻike kūloko o keʻano ukiuki hopena. Ua hoi ua analgesic a me ka antipyretic ka waiwai a i pili i ka e kaumaha ana ia ma luna o ka lolo.

Ke pharmacokinetic ano o

Ke kemu, ina e like me kaʻeleu 'Oponopono o ka lāʻau' like quinidine sulufahate? Na Ke Kumu no ka hoʻohana hoʻomaopopo 'o ia i? Eaia o ku una ha i Agena paipai' ana i kona nui lehulehu i loko o ke koko ma hope o 95 minuke.

Naoh o keia a me nā polokina medicament mea ma kahi o 77-80%. Kona biotransformation ia lŘlŘ ma ke akepaʻa. Naʻe, kekahi nā mea loaʻa i hana cardiotonic hana.

Ka hapa-ola o keia mea paahana o ka hola 7 hola. Ua Ua evacuated i loko o nā puʻupaʻa. By acidification o ka mimi excretion medicament, piʻi pū a me ka wā kona alkalization - inhibited.

Mai ka ua kuhikuhi?

He aha nō na nāʻikepili no ka hoʻohanaʻana i ka lāʻau, he "quinidine"? Na Ke Kumu no ka ho ohana i hākālia nō ia i ka manaʻo o ka lāʻau ua hoaponoia wale i loko o ka kēia hihia.

• ma atrial tachycardia, af-tachycardias, extrasystoles ventricular a me ka supraventricular, ho'āhewa wale o atrial fibrillation, a koliliʻana;
• e ālai 'ino o ka tachycardia (supraventricular a me ka ventricular), a me ka ventricular fibrillation;
• ma hope o ka cardioversion e malamaʻi i sinus pāpana.

Bans ka hoʻohana '

He aha nō i keʻano o ka hoʻomanawanui papa aku i ka hoʻohana 'ana o ka lapaʻauʻia "quinidine"? Na Ke Kumu no ka hoʻohana (ke kumukuai o ka laau helu 'ia ma lalo nei) papa hoike o contraindications o ka lāʻau', e like me:

• cardiogenic kŰia;
• Od-hihia (lua ole kolu o ka degere);
• thrombocytopenic purpura, i hoʻomohala ma hope o kona lawe ana i ka lāʻau;
• kāna hana (loa) intraventricular conduction;
• puolo lala hihia;
• digitalis intoxication, i ua pu ma conduction abnormalities;
• he allergic naoh i ka lāʻau;
• myasthenia gravis.

Medicament "quinidine": kauoha no ka hoʻohana

ʻae i ka mea paahana e ia i loko o 60 minuke ma mua ma hope o 125 minuke ma hope o ka palaoa me ka piha aniani o ka wai paha. Inā 'oe makemake e emi i ka irritant hopena o ka lāʻau ma luna o ka mucousʻili lahilahi o ka digestive'āpana, ia mea pono e puku i ka wai me ka waiū.

Hooloihi ae i lāʻau ua ole? Aeiiaiaoaony e mama ai e hoea.

Ka mea maʻamau laʻau heluna Ua noʻonoʻo pono 200-300 mg papaʻehā manawa i ka lā. Inā supraventricular tachycardia (me ka paroxysms) ua mahuahua i 400-600 mg keia dala o kela mea keia 3 hola mua piha ke ola o ka paroxysm. Ma atrial fibrillation, medicament loaa 200 mg kela 2 chasa (5-8 mau manawa kela la i keia). Ma ke aha ka malama mahele lāʻau mea 200-300 mg eha manawa i ka lā.

'Ano like regimens: 400 mg (ināʻaʻole i ka hoouka i docked, ka 200 mg) kela 60 minuke a piha hoopau wale o ke kaua, a no ka hoʻokō i ka huina laʻau heluna o 1 g.

I ka wa e kaawale aku o kaʻaoʻao 'ole ma hope o ka mahele lāʻau mua i loko o ka hope? Eaia o ka nui o ka medicament e e mahuahua i 600 mg. Lālau aʻela ia i ka lāʻau ma ka oi o ka 4 nā huna no lā ua pāpā.

Dosing no ka keiki

Ma kekahi mahele lāʻau o ka lapaʻauʻia i hoakaka ia no na keiki "quinidine Dyuruls"? Na Ke Kumu no ka hoʻohana 'ana, pediatricians lākiō i hoike i ka maʻamau laʻau heluna o keia Agena no keiki, he 6 mg / KG 5 manawa no ka lā. Prescribers E e wale he inā pilikia ka haumāna kauka, ikaika ma luna o ka pahu kānāwai.

Hana ma-ke ano

He aha hopena maikaʻi 'hopena kānāwai ma hope o hoʻohana o ka lāʻau "quinidine Durules"? Na Ke Kumu no ka hoʻohana 'ana, hōʻikeʻano o kēia k paipai i ka i kēia adverse reactions:

• asthenia, hoʻonui i ka QRS wā mawaena, myasthenia gravis;
• ectopic ventricular kui iho oe, e hoolohe ana ia poho;
• lilo o ka ikaika loa ka makemake, ventricular fibrillation, arterial thrombosis, haʻahaʻa ke koko;
• pilikia makapō haunaele, ventricular tachycardia, paroxysmal, tinnitus,
• asystole;
• nausea, sinus bradycardia, hepatitis, abdominal eha, hilahila;
• gastralgia, headache, ka luaʻi, thrombocytopenia, diarrhea, pōniuniu, hemolytic anaemia;
• wela, lupus-e like maʻi pale, ili wikiwiki.

hihia o ka overdose

He aha e hiki i ka lapaʻauʻia "quinidine Dyuruls" na symptoms o overdose? Na Ke Kumu, loa mai o ka poe akamai i olelo e pili ana i na hoikeana i tinnitus, kaumaha o cardiac hana, kulu i loko o ke koko,, pōniuniu, atrial kolili, diplopia, quinidine kŰia, lohe keia poho.

E hoʻopau i na Hawaii loli i hoakakaia gastric lavage, oxygen lako, hypertensive konohiki, i auhele, hemodialysis a me ka ventilator.

lāʻau hana kūleʻa

Pehea e hana i ka lāʻau hana me ka waiwai e like me quinine? Na Ke Kumu no ka hoʻohana (ke kumukuai hōʻike manaʻo o ka medicament e hōʻike mai iā ia, e ma ka pau 'ana o ka' atikala) hai i keia me ka hui pu maoli ka kaʻawahia o nā.

No hoi, "quinidine" huaale pāʻani aku me ka kēia lapaʻauʻia:

• Antiarrhythmic ai 'ka hōʻoi' cardiodepressive hana.
• Anticholinesterase ai 'a me ka lapaʻauʻia ka hōʻoi' na waiwai kalisodergaszczye "Quinidine".
• Anticonvulsant ai 'hōʻemi ai ke koko pae o "Quinidine" a emi kona laulā ma muli o ka stimulation o kona pūnao.
• Laxatives emi ka laulā a me ka lehulehu o ka lāʻau i loko o ke koko ma lalo o ka nāʻanaʻana.
• Lapaʻauʻia alkalising ka mimi, maoli i ka pilikia o kaʻawahia reactions.
• Ai ' "amiloride" a me ka "Amiodarone" emi i ka laulā o ka "Quinidine" a hooloihi kona wā mawaena QT, niioaaonoaaiii.
• Acetylsalicylicʻakika kŰlń ao kahe ana ke koko, petechiae a me ka paipai 'ia ka kahe ana ke koko mai ka digestive nā loko.
• Medicaments "Warfarin" a me ka "Verapamil" - hoʻokāʻoi anticoagulant kanawai o ka mua a me ka lua o ka hoemi ana o ke excretion.
• Uluwehi O "Haloperidol" - maoli kona maʻiʻo ma ke koko, a maoli he i ka pilikia o adverse reactions.
• Ai ' "Hydroxyzine" a me ka "dextromethorphan" - maoli ka likelihood o loa arrhythmia ma ka? Eaia o ka mua a me ka lua i loko o ke koko.

kiko'ī

Me ka kūikawā mālama nui ho'ākāka 'ia ma ka lapaʻauʻia paipai no ka maʻi naau nele ke kahua 2-3, tachyarrhythmia (ventricular) me ka elongation wā mawaena QT, sinus wahi, af-blockade 1st degere, asthma, hyperthyroidism, hypotension, huʻi infectious maʻi, emphysema , huina-panina glaucoma, hypokalemia, ake e loaa, thrombocytopenia, prostate hyperplasia, maʻiʻaʻa puʻuwai e hemahema, lactation, hāpai keiki, a psoriasis.

People me ka myocarditis a me nā myocardial maʻi i? Eaia "Quinidine" mau 'inikua e hooponopono ua koi' ia. Ma mua o lapaʻau, ka hoʻomanawanui pono e i? Iaea o na symptoms o hypokalemia a me ka ole o ka naau.

Ke Inc Ua koi 'ia i mau kanaka hoʻoponopono i ka ECGʻikepili o kaʻike ākea koko a me ka hemodynamics.

Similar ano, kuai

Uluwehi O analogues Ua noʻonoʻo i ka hailona. Poe akamai i ke kaila ia ia i ka i kēia mea: "Kinidin Durules", "Bretilat", "procainamide", "Etatsizin" "Lidocaine", "Amiokordin", "Propanorm", "Amiodarone" "Verapamil", "Propranolol", "Ritmonorm ".

Like no lakou i ke kala o na laau i "quinidine" a me ka "quinidine Durules", i ka poʻe i noho ma o ko mākou'āina, ka mea iʻikeʻole ma muli o ia ka mea e mau ai 'i hou kuai ma Rusia. Naʻe, ka mea hiki ke kuai i loko o Ukraine. Ke kāki o ka ai 'i loko o ka'āina nei ma kahi o 540 a me 670-679 hryvnia, niioaaonoaaiii, i mea like i ka 1380 a me 1760-1780 rubles.

Reviews

He aha kanaka olelo e pili ana i ka noʻonoʻo medicament kauka a me nā 'Oihana? E like me ia ia lakou, i kēia mea kökua ka proves e e loa ka hoʻokō antiarrhythmic lāʻau, i ka maikai a me ka hoʻokēʻai lawa e hana mai e like me ventricular a me supraventricular tachycardia. Naʻe, ka mea e e hoʻomaopopo i ka huli no "quinidine" Akala a ma Lūkini keʻena kūʻai lāʻau lapaʻau mea,ʻaʻole hiki. O ke kumu ho i ka mea i i hoʻokoe 'ia ka lapaʻauʻia mai noa holo, a ua hou ia i loko o ka haukapilaʻo. Kauka wehewehe i kēia kahua i ka mea i loaʻa nā lua pele a oi ka hoʻokō e like me affordable counterparts i loko o ka mea lāʻau lapaʻau kahi kuai, i ua 'Imi hoʻohana no ka mea ia nāʻikepili. Ma keia hihia, poe akamai i aku nei au ia quinidine sulufahate mau ia e hoʻohana i ka constituent o multicomponent 'ona i loko o na mea he nui Anati-arrhythmic ai'.