Treponema pallidum (Treponema pallidum) - ka causative Agena o ka syphilis

Treponema pallidum - he pilikia loa bacterium, ka causative Agena o syphilis. Ua hoʻomaka koke komo i loko o ke kanaka kino, a ma ka mea hookahi mämä ia hoʻopulapula, pela ka hoohuoi ana me ke kahaha nui o ka na nā loko.

Description koʻohune

Treponema pallidum - koʻohune me ka halepaahaoʻili lahilahi. Hiki i ka noho i kekahi manawa ma ke kaiapuni. Kēia bacterium e pili ana i na spirochaetes. Ua mau helehelena e like me ka meaʻuʻukuʻoni iho curls, i hiki ke mai ewalu i mau'āpana heʻumikumamālua. Just ma kā lākou nui a me ke ano o ka bacterium ua 'akomi i ka wā o ka haukaʻe i microscopy ua hana.

Kēia microorganism ua aneane nā pōpō make, a i hoʻohana ma microbiology. I mea e ike i ka bacterium hoʻohana Akä naÿe microscopy. O ke kumu ho i ka mea i ka iwi ka loa wiwi anakahi iki-meaola ma lalo o ka aoao o ka waiʻona, a kokeʻino wale (a me ka mea, ua pono ia no ka waihoʻoluʻu fixation). I ka kala-waihoʻoluʻu paʻa koʻohune ka mea, i mea eleele-ʻeleʻele waihoʻoluʻu.

Pehea lā ka lōʻihi o ola koʻohune

Treponema pallidum ma ka hui 'ana me nä mea like (ʻano nui kīhei pili a me ka pepa) ua mālama a hiki i ka kūpapakū maloo, i loko o ka mea ka mea, ua. Ka hapanui o na hihia tuha, kuu loli mai ulcers a me erosions, semen, a no laila, ma luna o. D. At ka wela o kanalima-kumamalima degere bacterium ke ola no ma kahi o umikumamalima minute. At kiekie ae make hou koke. Ma nā kapuahi e ka koʻohune make i loko o kekahi mea o nā kekona, i mea, aneane e loaa ia.

I mea detrimental i koʻohune

No ka Treponema pallidum i kekahi mau palapala i hoʻolilo 'ia a me ka' ona:

• bismuth a me arsenic;
• Mercury;
• penicillin;
• mekala 'åkilikai a me kaʻakika;
• antiseptics a disinfectants;
• vinega a me ka waiʻona;
• UFO a me ka malamalama.

E like me ka haʻawina a me ka ike maopopo ana i lawelawe 'ia e nä känaka' epekema, ka mea i loaʻa iā ia i kēia bacterium hiki i kekahi manawa, hoomau aku no i kekahi manawa, a ma adverse aku ana no ka mea. No ka laʻana, i loko o ka ino 'ia, ma lalo o ka malamalama, i ka maloo ana a me ke alo o ka oxygen. Inā 'oe e hele mai ma ke kope o ka microorganism, ka mea hiki ke noho i loko o kaʻenemi o nā papa hana no ia i ka makahiki ekolu.

Treponema ka ulu a me ka nui antigens

Treponema pallidum poorly mahi no ka mea, o kona capriciousness. Ke keena o ka chick embryos a me kanaka mea e pono no ka mahi ana i keia meaola. Aia nō i nā alaʻelua, pehea moʻomeheu hiki ke hōʻike '. Ka mua - ka koʻohune iho mailoko o keʻena hoʻokolohua 'Olu, a kali no ka hooulu ana i kēia mau holoholona kekahi orchitis. Apana - treponemu hiki ke makua ma luna o kūikawā me Media, ma lalo o mea pōhaku i ka aila. Ke alo aku o kēia mau meaola mea pono e kiʻi i nā antigens me i syphilis ua nānā '.

Pathogenicity Treponema pallidum

Pathogenic koʻohune treponema pallidum i kona mau 'ano:

• mahalo i ka adhesin kumuʻiʻo e hana me ka fibronectin mucosal hoʻolako "sticking" e kahua keena;
• i ke alo o nā myofibrils a me kaʻoni iho shape Treponema pallidum paipai iʻoi anal, a i ka neʻekau o ke kino;
• antifagotsitarnaya ha awina mea ku pono i ka hiki ana o na koʻohune, e nakinaki ia fibronectin;
• i wela ai ma muli o ia i ke alo o ka lipoprotein membranes;
• treponema pallidum hoʻopale i antibacterial konohiki aie i ka variability o ka antigenic waiwai, a me ka hiki ana o ke kahua o ka L-ano, aʻo ka mea hiki ole ke hana i kekahi laʻau koʻokoʻo;
• Mau koʻohune mea ole wale hiki ke noho i loko o nā interstices, akā, no hoi, e mahuahua ma laila.

Nā mea'aʻaʻa i Treponema pallidum

Treponema pallidum uaʻano nui i ohi ia i loko o ka mucous membranes. No laila, hiki wawe ka pū i hiki ole wale ma ka moe ke keakea ole, akā, i loko o maʻamau o ke ola. Loa pinepine ma na pepa, ipu a honi iho la i. Eia naʻe, i ke kanaka kino hiki ole hoʻomōhala e hoʻonele ai i kēia mau koʻohune. No ia mea, e like ma hope piha hoolaia o syphilis maʻi hiki hoʻi.

No ka hooholo ua ia i ke koko maʻi i syphilis. Ka hapa nui o ka iho mailoko o i nā mea'aʻaʻa i Treponema pallidum. Ma iniiaiie a recurrent mai - i loko o 88 a me 78%, niioaaonoaaiii. Ke koena ka mea, i kekahi i detectable ai 'ole-existent. Akā, i ka wa e kaawale aku o nā mea'aʻaʻa, aole ia e hooiaio mai i ka iapaau ana ka holomua. Ma ka latent ke kahua o ka maʻi lāʻau lapaʻau kino nui i loaʻa wale nō i loko o 20 pakeneka o ka hoʻomanawanui iki mai.

Ma hope o 1-2 pule, mai ka hoomaka ana mai o na kanaka i loohia mai ia hoʻi i ka lāʻau lapaʻau Ka Ikepili. IgM a IgA nā mea'aʻaʻa e treponema pallidum ma ka lāʻau lapaʻauʻikeʻia i loko o kēia wā. I loko o ka manawa mai ka eono mahina i eiwa mahina titers o immunoglobulin ulu, a laila, hoʻomaka hoemi lākou mau mea. Ma manawa ka mea, e hina ia ma lalo o ka manao o lakou waiwai, a me ka nui o nā mea'aʻaʻa. Kekahi hiki ole ke pū i hiki mai ka makuahine i ke keiki.

IgG nā mea'aʻaʻa hou 3-4 pule ma hope o maʻiʻaʻai me syphilis. A 6-9 hebedoma e hiki kona piko. A nui lehulehu o ka lāʻau lapaʻau kino ua mālama 'ia no ka lōʻihi manawa, a me ka emi loa lohi, a ma hope o Inc wale. A koena titers e hoomau anei ma ke kino no ke ola.

Treponemal nā mea'aʻaʻa hiki ke hua mai la wale e Treponema pallidum. Nolaila, i ka wa a ko lakou alo hiki pololei koi ia syphilis mea ma ka manawa a ua, ua nee aku no ia mamua.

Symptoms o ka maʻiʻaʻai o Treponema pallidum

Aia i kekahi helu o symptoms hōʻike mai ai i ke alo i loko o ke kino o ke kanaka Treponema pallidum. A hiki aku ka mea, māʻamaʻama e pono ai, e lūlū i ke koko no ka syphilis. Symptoms e oko ma ke kahua o ka maʻi.

Ma ka mua:

• ola na mai hehe ikea me ka chancre, Aia i loko o ka waha, rectum paha genitalia;
• pehu lymph aka wahi;
• kū kaʻawale ulcers i puakai ma ka liʻiliʻi loa ekolu pule, i ke kaʻina hana hiki mau mai i eono mahina.

Ma ka lua:

• symmetrical haikea syphilitic poʻe noʻonoʻoʻole i ikea mai ai ma luna o ke kino;
• headache, malaise, kuni;
• pehu lymph aka wahi;
• kekahi manawa, losing kona lauoho, a me ka wahine warts māʻamaʻama lehulehu.

I ke kolu o ka mea, he make.

• ko mākou hopohopo kahua;
• lolo a me ka spinal ke kaula;
• na nā loko;
• iwi.

Ma ka mea mua a me ka lua o ka kahua o ka hoʻonaʻauao ka pono hulina lapaʻau i nā antibiotics, physiotherapy, bracing a me immunostimulants hoomakaukau. Akā, inā manawa, aole ia e ike i ke kauka, a laila, he mau makahiki ma hopeʻo ia ka hoʻomaka 'ana i ke kolu o ke kahua o ka maʻi, e hoola i ka mea aneane hiki ole i.

E like me ka weheia haikea treponema?

E ike ai i ko laila mea i loko o ke kino o ka koʻohune mea i syphilis, ia mea he Ikepili kūpono. Treponema pallidum hana o kēia lapaau Hiki ke huai ae i loko o kekahi mau aoao:

• Ma ke kahua mua o syphilis ka hoʻomanawanui mea i aloha lele a me ka Naauao ma ka honua i ka hailona o koʻohune. Ma keia hihia i ka haukaʻe i microscopy. E kiʻi pololei hualoaʻa, ulcers ia me ka Saline washout no, keakea e flora. A lailaʻo ia i ka hamoʻia, a i ka haukaʻe.
• Ole-treponemal ho'āʻo ma. Aia hoʻohana loiloi ki ina hana like. Ka mea, he mea maikai no ka loiloi muaʻike, a me ka pane mai i lapaau, a me ka lapaʻau ninaninau. Akā, i kēia mau ho'āʻo ma pinepine haawi wahahee maikaʻi hopena. Treponema pallidum ma keia hihia e ole e noho i loko o ke kino. He no ka mea, hypertension (nā mea'aʻaʻa ku e antigens) ka mea,ʻaʻole i lawe pathogen.
• Treponemal e ho'āʻo ai i hoʻohana mea e huai ae Treponema pallidum. Kēia mau kiʻina hana i hoʻohana e hōʻoia i kaʻike, a me ka loa o syphilis ma ka hewa loiloi hoao.