"5-NOC" - hōʻike manaʻo o ka la hoomalolo

I loko nō o ka mea i ua hāʻawi i hoʻonele i ke kanaka kino a me ka mea hiki ke Makuakane i loohia i na mea he nui wale, aia nā mea koʻohune a me nā mea palahēhē mea e lanakila a me ke kōkua o ka lapaʻauʻia wale hiki. Ia ai 'hiki inhibit a pau ana ka ulu ana o ka pathogenic meaola, hiki ke kāpaeʻana i ka pulakaumaka o ka li nui. Papa i "5-NOC" ka pae ana o ia ai '. E hoike hōʻike lākou kiʻekiʻe hopenaʻoi loa i loko o ka iapaau ana o ka maʻi o ka genitourinary nenoaiu. Eia hou kekahi, keia mea paahana mea hemolele no ka Kāohiʻana o ka recurrence o ka li nui i loko o maʻi ano o ka maʻi.

ʻeleu waiwai

Nitroxolineʻeleu waiwai o kaʻeleu lāʻau "NOC-5." He He kemikala ho okumu, he derivative o 8-hydroxyquinoline. Ma keia ke keʻena, ai ka lāʻau komo i ke kino hoʻomaka e nana i keena o microorganisms a inhibit lākou DNA. e waeʻano papa hana o ka 'ana e leie aku, e hooki aku i ka ka hoʻonuiʻana o pathogenic koʻohune, aʻaʻole pilikia ola keena.

Ma waho nitroksolin komo i loko o naoh me kaʻeleu nukelea nāʻakika a me nā'ūhū i pihaʻi me ke hooheheeia i loko o kā lākou mau hīnaʻi manu. I ka waiwai i haawi mai i ka loaa kaʻina hana o pathogenic koʻohune mai i ka ikaika bactericidal 'ana no ka laulā pae o microorganisms. Pela ia ka pono hana ku ei ke kanana nei hoʻopale i ka ai '' ē aʻe hui o antibiotics. Medicine "NOC-5 'lākiō i ua hookupaa iho la ia ia e ka pono a me ka inexpensive mea e ku e mai, kena ae la ia e fungi, koʻohune, a me ka maʻi-ma o na la pathogens kiʻekiʻe ia'ku i nā ai' o antibacterial a me ka antiseptic hana.

Release palapala a me ka haku mele 'ana

Ke medicament Ua hookuu ia ma ke ano o ke kapa komo iā ia papa. Ka mea, i alani paha melemele, ma ka palapala o ka puni, lenticular, aia no he ano alohilohi. I ka papa kuhikuhiEʻeleu 'Oponopono - nitroksolin. Kākoʻo eiiiiiaiou o ka haku mele: sucrose, colorant E110, carboxymethylcellulose, lactose.

He aha microorganisms kaua lāʻau

E noke i ka hoʻomanaʻo i ka directional ai a me ka mea he mana e ku e kekahi ke kanana nei o pathogens:

• Aerobic a anaerobic Gram-maikaʻi meaola - Enterococcus faecalis, Streptococcus spp. (Pneumoniae ke kanana nei, pyogenes).
• Staphylococcus spp., Ke kanana nei aureus, Bacillus subtilis, Corynebacterium spp.
• Anaerobic a aerobic microorganisms (gram) - Klebsiella spp, Proteus spp, Shigella spp, Salmonella spp, Haemophilus influenzae, Enterobacter spp, Escherichia coli, Neisseria gonorrhoeae ......
• Nā mea palahēhē kena ae la ma o ka Mycobacterium tuberculosis, o ka Mycoplasma hominis, Trichomonas vaginalis, o ka Ureaplasma urealyticum.

Ka hopena he, dermatophytes, fungi o Candida, kekahi meaola ma o na la hohonu fungal nā mea palahēhē - kēia mau maʻi i kekahi mana ma ka hoemi lāʻau ' "5-NOC". Reviews o kauka h ÷ ike i ka hiki mai o ka lāʻau, e emi i ka mea pīlali o uropathogenic meaola a hiki i ka pa o ka catheter (e omo mimi, mai nā mea maʻi) a me ka urinary'āpana epithelial, ahu iho.

wā lawelawe

Ma muli o ia i kekahiʻano laulā huahelu o ka lāʻau palapala noi, e Makuakane me ka kēia illnesses:

• Maʻi, huʻi, recurrent maʻi (infectious etiology) urinary'āpana, kena ae la ia e Gram-io a me Gram-maikaʻi koʻohune a me fungi.
• Epididymitis.
• Pyelonephritis: maʻi a me ka huʻi ano.
• Urethritis.
• Cystitis.
• Adenoma a me ka carcinoma (maikaʻi) o ka prostate.
• Pale nā mea palahēhē (recurrent) urinary'āpana.
• Pili ma hope o PalekanaEND_LINK, aʻoki lāʻau lapaʻau kaʻina hana i loko o ka urinary'āpana: hakuʻalaʻoki kino, cystoscopy, catheterization.

It O ke kumukuai o 'ana i kumumanaʻo ana i koi' ia e pono lapaau ke kaumaha ma muli o ka oolea o ka maʻi hiki wale nō ia i ke kauka. Papa "5-NOC" poe akamai i hōʻike manaʻo ka mea, ua hoʻoliloʻoe i kiʻekiʻe bioavailability - ma kahi o 90%. Ua hoʻomaka koke ke kemu i loko o ka gastrointestinal'āpana, a hiki aku i ka lani kiekie loa wai koko lehulehu i loko o 1.5-2 hola.

Pharmacokinetics

Ka makaukau i ka haʻahaʻa hana e hui pu iho la me ka wai koko nā polokina. I ka lani kiekie loa lehulehu o kaʻeleu waiwai hōʻike i loko o ka mimi o ka hoʻomanawanui. Ka lāʻau 'Ua metabolized kuhikuhi i loko o ke ake, a excreted ma nā puʻupaʻa. A kekahi dala o ka lāʻau ua wehe 'ia mai ke kino i loko o ka bile - he au o ka 2 hola E e hoʻomaopopo i ka' ikepili ma luna o nā pharmacokinetics o ka lāʻau i loko o nā keiki, kanaka i ka elemakule, a me nā mea maʻi me kaʻaʻa puʻuwai insufficiency a me ka ake i ole ua? Anoee .. Nolaila, e pono e kiʻi i ka palapala hōʻoia no kauka kukakuka mua kuhikuhi huaale "5-NOC". Reviews mau loea, e hoailona oukou iaʻano maikaʻi tolerated keiki ka lapaʻauʻia ma ka hihia o ka piha kaʻaeʻana i ka laʻau heluna a me ka lapaʻau regimens. Mau malama e alakai i ke keiki kilo, a i ole ma 3 makahiki o ka makahiki.

Pehea e lawe

? Aeiiaiaiaaia e lawe i ka lāʻau i meaʻai a ma hope o ia. Papa e mai a nau hou, ke ale wale iho a pau, holoi iho la me ka wai maemae. Kūpono nā māhele:

• Kanaka makua hoʻomanawanui iki mai - 100 a hiki i 200 mg, i ia 4 manawa i ka lā. E noke ma lalo o keʻano o ke ana pono o ka papa ana, hiki ole mamua o 30 lā. Naʻe, i ka hiki papa o ka Inc me ka alternation: 14 lā inu na papa, 14 lā i lawe i ka waiʻona. Keia papa hana i ka mea e hiki ai i ka i iapaau ana no kekahi mau mahina.
• Kāohiʻana o infectious maʻi ma hope oʻoki lāʻau lapaʻau ke kaʻina hana, PalekanaEND_LINK hana - 100 mg i ka 4 manawa i ka lā. Oia medicament? Eaia? Aaeei mau mai i 3 pule. No nā mea maʻi me kaʻole ake hana a me ka hakuʻala loiloi mua mahele lāʻau o 50% o ka paipai.

It E e hoʻomaopopo i ka lāʻau 'o "5-NOC" cystitis, ahonui e hoike e hooiaio aku i kēia, koke ho'ēmi i kā li nui, a eliminatesʻoi eha. Eia naʻe, i loko o ka hanana o ka maikaʻi loa o ka lapaʻau ua i waiho e alalai mai i ka papa i hoakaka ia ma ke kauka, i ole ia he mea he pilikia o ka recurrence.

Ka laʻau heluna no ka keiki

E hoʻomanaʻoʻoukou i ka pono laʻau heluna no ke keiki ke kuhikuhi wale nō ke kauka ma ke kumu o ke anamanaʻo. ka lāʻau ua ana i koi 'ia penei:

• Keiki mai ka 2 a hiki i 12 mahina i ka ho omaulia ua i, ma muli o ka pēpē ka kino kaupaona: 25 mg / kg no ka lā. A pau ka lapaʻauʻia e ke maheleia i 4 nā māhele i mauʻanuʻu. Duration o ka Inc mea mai 10 mau lā a hiki i 3 pule. I Ina o loa maʻiʻaʻai - mai i 1 mahina.
• I ka makahiki o ka 12 mahina i ka 14 makahiki i hoakakaiaʻai ana o ka 50 a hiki i 100 mg i ka 4 manawa i ka lā. I ka holo ana me ka nānā 'ana i ka hoʻomalu, akā, me ka ana? Eaia mea hiki ole mamua o 30 lā. I ka wā o ka interleaved aaeei 2 hebedoma -? Eaia, a me 2 pule - ka mokuāhana ua ae no ka hana hou ana i ka lāʻau ' "5-NOC". Keiki, kauka hōʻike manaʻo e pili ana i kēia hōʻike hoʻi e e hoakaka ia wale nō i loko o loa hihia wā hana maikaʻiʻole a me nā laau hoao ineffective.

Hikiʻaoʻao waiwai

E noke i kaʻaoʻao waiwai i loko o nā mea maʻi e pohihihi keia, aka, ia mea e pono ai ma ka hopena o ko lākou mau hanana koke leka uila i ke kauka. I ka mea i ana i ka lāʻau a me ka hoʻomaka symptomatic hana ma hope o lapaʻau "5-NOC". Instruction Nāʻana na kumu paipai i ke kēia hopena maikaʻi 'hoike ana i loko o ka iapaau ana o:

• Ka luaʻi,'āno'ē ake hana, nausea, anorexia, ma ka pohihihi keia hihia.
• Tachycardia.
• Paresthesia, polyneuropathy.
• Hoʻopōʻino ōhumu, pōniuniu, headache, i kekahi manawa, lilo o ka ike paka i.
• Optic neuritis (me ka hooloihi ae i lawe papa).
• Urticaria, poʻe noʻonoʻoʻole, kaha onionio ili.
• Thrombocytopenia, i kekahi manawa mimi i hookohu aku i ka hohonu yellow hue, he hoomahuahua i uricʻakika inideka i loko o ke koko wai koko.

E like me ka rula, adverse hanana a pau e holo koke ma hope piha discontinuation o ka lāʻau, "5-NOC". E hoike hōʻike oe haha aku unwell, wale i ka hihia o ka overdose a hune kaʻaeʻana.

Contraindications

Inā ke hoʻomanawanui i ka allergic naoh paha pā lonoaʻili i kekahi o na eiiiiiaiou o ka haku mele 'ana, ka mea, ua papaia e hāʻawi i ka waiʻona. Ua UaʻAʻole pono e pili i ka medicament ma breastfeeding, cataracts,'āno'ē ake kuleana pili i a me ka hakuʻala.

Ua mea waiwai 'ana i kumumanaʻo ana i ka lāʻau' o "5-NOC" wahine manaʻo e pili ana i kēia hōʻike ua pinepine hoakaka i hāpai keiki. Ia, aole ia e hookupaa aku i na hihia o ka ino a hiki i ke ola o nā ka wā e hiki mai makuahine, a me ka fetus. Nō kāu, i ka lāʻau 'ua hoakaka ia no ka huʻi cystitis, vaginal nā mea palahēhē a me fungal hoikeana (thrush).

Ia mea,ʻaʻole e pono ke lawe i ka lapaau i ka mea ia manawa me ka laau i loaʻa hydroxyquinoline. ʻawahia kaʻapu kōheoheo ke'ākoʻakoʻa, mai ka loaʻa pākeu oʻeleu waiwai i loko o ke kino.