Bacteriophages: ano a me ka manao

Phage lysis - i ke kaʻina hana o ka luku ana o koʻohune ma phages, i hookuu ia lŘlŘ i loko o ka iʻa hui, ma noho'na makaainana i ulu ke ola. Inā pakiko-hoola i ole ana, i ke kino hiki ke kōkua ma ka like bacteriophage i hoʻolaunaʻia ma, kūpono i ka mea lāʻau lapaʻau huakai. Kapa bacteriophages nā mea hoʻomaʻi koʻohune i komo iloko, a i ko lakou noho male 'ana (lysis) ma ka halawai ana me ia susceptible i microbial keena.

Ma Greek bacteriophage 'o ia hoʻi "eʻai ana o koʻohune." Ma ke ano maoli, i kēia mau meaola ua loa like, aʻo ka nui o ka a ianoiyuaa a ike mea hoʻomaʻi pūʻulu. Phages i nā mea hoʻomaʻi okoa, mai mea kanu, a me ka holoholona kanaka 'ole, oi eiiieaena. Ka mea i loaʻa i loko o ke kimu ole, ea, ka lepo, ka ai, i na kanakaʻili, holoholona hulu hipa, ma ka pōkole, na wahi a pau he mau koʻohune.

Ma nā makahiki, he lālā hua ma ka hoihoi bacteriophages e hoʻohana i kekahi koho no antibiotics. Kēia mea e kahaha ko oukou naau, a me ka poe a me ka 'ē aʻe ai' pololei pili i nā pathogens. Eia naʻe, ua ikeia antibiotics detrimental hopena ole wale ma luna o ka pathogenic flora, akā, no hoi no ka mea pili i ka hoʻoponopono. Bacteriophages, nāʻano o i mea okoa, hana selectively, wale no "ko lakou" koʻohune, e waiho ana i ka piha'ā o ia. Maoli, no laila,ʻepekema, a i inoa,ʻaʻole invent ia, ia mea nui maʻalahi e kapa aku ia lakou pakahi ka koʻohune e a lakou i waiho kokoke ana.

Bacteriophages: Kind

Ulu streptococcal, coliform Proteaceae, klebsiellezny, Staphylococcus, Pseudomonas, Salmonella, ka hī koko, typhoid bacteriophage like hoʻi me "Intestifag" a me ka "Piobakteriofag".

Hana hoomakaukau Ua nānā 'ma kā lākou degere o ka dilution ma i ka lysis ikepili koʻikoʻi moʻomeheu. Penei, titer o 10 i loko o ka lua o ka degere o ia hoʻi, i ho'āʻoʻia lytic bacteriophage hana waiwai ma ka dilution o 1 000 000 manawa. I ka wela o ka 4-6 C ai 'ka mea, hoopaa i ko lakou waiwai i ka 12 makahiki.

Ke kaumaha ma muli o ka kala pepa oko ma hope bacteriophages. Ano o ka ai 'mea e loli i nā ke kanaka pathogens, a ma luna o kekahi i kekahi manawa. Monophages loli mau ke kanana nei o ka ia koʻohune. K eiiieaena hoomakaukau (polyvalent) nā bacteriophage "Sekstafag" i mea hiki ke ka poʻe inhibit i ka ha awina o staphylococci, streptococci, a me enterococci, Pseudomonas a me Escherichia coli, Proteus, Klebsiella. Eia kekahi, aia no he "Intestifag" manao ia no ka iapaau ana o intestinal nā mea palahēhē, ia maupaʻa he Salmonella, typhoid, ka hī koko, proteus, coli a me streptococcal (uhi enterococci) phages.

Ai 'hoʻohana' ia i loko o dysbacteriosis, intestinal nā mea palahēhē, aku aat o ka urogenital'ōnaehana a me ka broncho-pulmonary i hoʻomākaukauʻia no ka hana maikaʻi septic keʻano o ka hanaʻana, e like me ka pono i nā maʻi o ku una ha i ka lua a me ka sinuses. Ka mea, i hoʻohana 'ia me ka loko, a me loko o ka palapala o enemas, a me nā Tuamotu - e holoiʻia ia, holoi palapū, douching. No ka laʻana, "Ka Bacteriophage Klebsiella polyvalent hoomaemae" no ka iapaau ana ozeny, rinoskleromy, nā mea palahēhē kena ae la ia e ka bacterium Klebsiella pneumonia, hoʻohana 'ia e inhalation ma lesions trachea, larynx a me ka pharynx, lawelawe turundaʻona nō i loko o ke kinowai, otitis, hoʻohana' ia no ka holoi ana i loko o sinusitis. I ka cystitis, enterocolitis, urethritis, pneumonia lāʻau ua lawe hōʻike waha.

Bacteriophages i ka nui o ka pono ma luna o antibiotics. Ka mea, i oleʻaoʻao waiwai, e ia ka mea, a hiki i keiki a me ka hapai nā wāhine, ka mea, i ole addictive. Ka mea, hiki ke hui me kekahi ai ', e like me ka hoʻohana' ia no ka Kāohiʻana o infectious ka maʻi. Kēia mau hoomakaukau i ka pono ole ma luna o ka ulu o hoʻonele, mai uhi i ka flora maoli a me kā lākou hooko Ua akaka no ka puka i loko o 2-4 hola ma hope, inu. Ka mea, e i hoʻomōhala ia'ku pathogens.

Kekahi drawback nā bacteriophages. Ano o ka hoʻohana 'ia i kēia lā ma ka lapaau, aka, mau, a hoʻohaiki ana kā lākou hana i na mea he nui nā mea palahēhē.

Outlook noi

I mea e ana pili liluwelo huahana, ia mea pono e hooholo i ka pā lonoaʻili o koʻohune ia ia. Eia naʻe, ua ike epekema he hoihoi 'kumu: ua i hoemiia ka pā lonoaʻili o microorganisms i phages, akā, e aho maoli, aie i ka enrichment o nā huahana me ka hou hana' ike loea. I ka lā, i ka bacteriophage staphylococcal ana lyse 90% o nā mea a pau ke kanana nei o ka koʻohune hookuu i septic lesions.

He nui infectious maʻi hoʻomalu manaʻo i phage Inc e koke revolutionize i ke kaua e kū'ē i nā maʻi. Immunologists ike i ka ana o ka pono o kēia mau dala kahi Immunopreparat powerless. E like me ka mākau haʻawina ma ka kekahi mau makahiki, kekahi o ka loa, olelo pomaikai oia mau mea o ka pharmacology e e ka-i? Iecaianoaaiiuo o phages.