E kau platelet? Iecaianoaaiiuo. 'Ole a me ka hana ana o platelets

Ka uuku ke koko aeee i platelets. Ka mea, nana e like me ka nukelea-noa kipaku aku ai. Lākou anawaena hoʻoneʻe 'ia paha i ka 4 microns, a me ka mānoanoa - mai i 0,75 microns. Kēlā me kēia hano o kanaka koko platelet ka leo mea ma mai ka 180 a hiki i 350 m 10 ^9.

Ke ala o ka helehelena o platelets

Platelets hou i loko o ka fragmentation o ka cytoplasm. Ka mea, i kaawale ma ka nunui iwi lolo keena - megakaryocytes. Lakou, ma ka huli, i ka hopena o ka endomitosis. Ma hope o kaawale ia lŘlŘ 3-5 pōʻaiapuni, oiai i ka chromosomes i maalahi loa, akā, ua i puʻunaueʻia ka cytoplasm. Kēia kaʻina poe akamai i kapa kāpili moku.

He nui e ike i ka wahi o ke kahua o nā platelets - he ula iwi ka lolo. Mai keia e hele mai la lakou, a komo i ka koko. Akā, me ka hapakolu o ia i koke waiho i loko o ka spleen. O ke kumu ho i ka ke kua'āina o kā lākou mau ana ma ka meandering kaula spleen. Ke koe 2/3 e hoʻolahaʻia i loko o ke koko o ka awelika o nā lāʻehiku. I kā mākou ola kīkoʻo kona hiki a hiki i 12 mau lā.

Ka nucleation papa

E maopopo pehea loaʻa nō i ka huna uuku koko keena, ia mea e pono ke ike i wale i ka wahi o platelet ho okumu. He nui e möakäka hou i ke kaʻina hana o ko lākou ulu. No laila, ka mea, o ke kupuna o ka megakaryoblasts. Ua nui ke kelepona hele nui ana i ka 20 microns me ka Kora naʻEsau. Ua na nucleotides. Megakaryoblasts iho i loko o promegakaryocyte. Kēia 'ole mea prone i ka polimorfizu nucleus, cytoplasm kona hua liilii,-noa, basophilic.

I kekahi kahua o ka? Acaeoey o ka megakaryocyte. Kēia, alahula aeea ma ka iwi ka lolo, i ke anawaena o ka i mea mai ka 60 a hiki i 120 microns. He He hoʻonaninani Kora naʻEsau, i hiki ke lawe i ka loa bizarre palapala. Ke cytoplasm ia mea nui ma ka nui, ia mea he granular inclusions o nonono a me ka poni.

Ke penultimate ke kahua o keʻano o ka megakaryocyte trombotsitogennogo. Ma hope ona ua ola 'ana platelets. Ka mea i kaawale mai o ka cytoplasm megakaryocyte. A pau keia e wahi i loko o ka iwi lolo o ka iniiaiie paena o platelet ho okumu.

hoʻokaʻawale papa

Trombotsitogennye megakaryocytes i loko o ka iwi lolo mea ma luna o ka endothelial luna, i kapaʻia ka sinus. Lākou cytoplasmic keʻano o ka hanaʻana ma waena ia. komo iloko o kekahi o ia mau mea i loko o ka sinus lumen 1-2 microns, a paa ma ka megakaryocyte endothelium. Ka mea, e malama me ka heleuma. Other keʻano o ka hanaʻana - he lōʻihi cytoplasmic leki lōʻihi ke hele mai i 120 microns. Ka mea, e hele ma ka lumen o ka sinus. Ka mea, i kapaʻia prothrombocytes. Kēlā me kēia megakaryocyte hiki e mai ka 6 a 8.

hualoaʻa ka ho'ēmiʻana o ka cytoplasm hoʻomaka ma ka sinus lumen. E like me ka hopena, e ka mea i haki, a he mea ka hola 1000 kanaka platelets. Kēia wahi platelet ho okumu 'aʻole i hiki mau. O ke kumu ho i ka mea i loko o ke koko e haule iho no hoi prothrombocytes. Ua hiki aku i ka akemāmā microvasculature, malaila i hookuu piha platelets. I mea no ke aha la he mea nui o ia mau mea i loko o ka pulmonary aa koko ma mua i loko o ka like arteries. He kupaianaha i ka mea hiki ke hana a hiki mai ka 7 a hiki i 17% o ka platelets maalo ae la oia ma ke koko.

'ano o nā keena

Poe akamai i maopopo kekahi mau ano o ka mea uuku koko keena. Kaawale kaʻawale opiopio platelets. Ke hoʻohālikelike a me oʻo pepa ka mea, i hookoaiaʻe e kŘpa a nui nui, sparse grit a me bluish gialomer. Lākou ho okumu ololi hoʻokāʻoi 'iwi ka lolo, ka mea, ua pinepine me ka nui koko poho hou pili.

Ka mea, oko i ka nānā aku a me ka mea kahiko platelets. ma lalo o ka microscope kiʻi e leie aku mākou, e noonoo i ka mea, i kekahi wahi paiki Park, he nui helu o vacuoles a me granules. Ka mea, oko ole contours, pilipaa granulomerom e hiki hoopiha i ka platelet holoʻokoʻa. Excessive lākou helu Hōʻike i ka helehelena o ka malignantʻeho.

Kaawale, loaa hou ano o ka mea ukiuki loa. Ua otshnurovaniya mai megakaryocytes hōʻike i ka 'aʻe o ke kaawale ana kaʻina. Lākou alo hoike i na maʻi o ke koko. Ka mea, pinepine nana e like uuku paha, conversely, kanaka nunui platelets kanaka koko.

Maʻamau, pono e i ke koko oi ma mua o 90% o ka oo helehelena o platelets. Ka mea, i ka discoidal shape me kaʻoi lua nāna, granulomerom manaʻo nui ka hooponopono ia, a he o 5-20 azurophilic granules, lilac gialomerom.

keʻano o ka hanaʻana o ke ola

Hōʻike 'ia ma ka iwi lolo, aeee haʻalele i ka papa kuhikuhiE wahi o platelet ho okumu. Ma ke ala, i ko lakou? Iecaianoaaiiie ka hooponopono ana i trombotsitopoetinami. Lakou, ma ka huli, hōʻike,ʻaʻole wale nō i loko o ka iwi lolo, akā, i ka spleen a me ka akepaʻa. Poe akamai i kuhikuhi i mau trombotsitopoetinov pae. Ka mea hiki e lōʻihi paha pōkole-kau hana. I ka mua o ia ka paipai 'ana piha maturation a me differentiation o megakaryocytes, a me ka hope, ka hōʻoi' i ka cleavage o kēia mau meaʻuʻuku papa, a hōʻeleu i kā lākou anal i loko o ke koko.

e luku Platelets, kona kiʻi hiki ke ike ma mau mahuahua, ma ka awelika, he hebedoma hana. Kēia kaʻina hana i wahiʻano nui i loko o ka iwi lolo, akā, i decompose mau keena ke koko i loko o ka spleen a me ka akepaʻa. I ka luku i wahi ma kūikawā'ōnaehana aeee kapa macrophages.

'ole mai o nā moʻolelo

Kēlā me kēia oʻo platelet hiki ke maheleia i ekolu cii. ʻike ākea hapa poe trilayerʻili lahilahi. Ua loaʻa receptors no collagen, serotonin, thrombin, epinephrine, ADP. Ma ka hapa ma waho o kaʻili lahilahi mea kūikawā amorphous, ahu iho oia o nā kumumea kuleana no ka clotting o ke koko wai koko.

Middle, ahu iho o ka Sol-tuko pīlali. Aia i kūikawā kaha i komo i ka mawaho o kaʻili lahilahi. No hoi, ahu iho maupaʻa microfilaments kuleana no ka iwi kuamoʻo-hoʻokino papa. Ka waiwai o keia hapa o ka platelet hilinaʻi nui ma pehea e e he retraction o ke koko clot.

I kaʻawale organelles ciia. Ua loaʻa glycogen a me Alpha-granules, anuanu kino, na mitochondria.

oihana

E aʻo pehea e hōʻike i ho'ākāka 'ia (particles) uuku o ke koko, nui ka poe i hoomaka, e kahaha no ka mea platelets. Ka mea, i manaoia e komo i loko o hemostasis, kōkua? Aiiio poino na moku koko. Keia ua i hiki ai i ke aloha a hiki i ka mea i ka mea, hiki e pili ana i ka poino pa, a hoʻihoʻi aku iā lākou. No hoi, e koi mau keena e pale kahe ana ke koko, a me ka iniiaiie ia auoiaea liluwelo fluids mai ke koko.

I nā hooko ana i olelo mai platelet oihana waiwai: mea pīlali a me ka aggregation. No laila, kapa aku ia lakou i ka hiki i ka e pili ana i subendothelium a pili pu.