"Farmadipin" (kulu) mai ka mea?

Currently, he nui na kekahi mau laau no ka hypertension a me ka ho'āhewa wale stenokardicheskie. Kekahi o ia mea no hoi e like me "Farmadipin" (kulu) lapaau. He aha ke ano o keia k, a kūkākūkā hou i loko o au mamuli.

'ole

Kaʻeleu 'Oponopono ma keia hihia ka nifedipine (nifedipine). 1 ml o keia pāʻoihana, ia mea i loko o ka kekahi dala. Oia, ma ka 100%, ma muli o ka maloo-type substance - 20 mg. Ua huli kanakolu kulu.

"Farmadipin" (droplets), ke aʻo ia i ka palapala noi e e kūkā mai ma lalo, ma ka 'ole o ke alo o ke kākoʻo' ona e like me polyethylene glycol 400 a me 96% ethanol.

pharmacological waiwai

Kēia lāʻau i ka hoailona pharmacodynamics. Me ua i haiia ae maluna, o ka "Farmadipin" (kulu) kekahi mau nifedipine waiwai e hoʻolako antihypertensive a me Anati-anginal hana. Ua paipai 'ana i ka paleʻana e komo aku ai o ke kalipuna Ion i cardiomyocytes a laumania Muscle aeee i loko o kekahiʻike ākea, a coronary arteries ma ke anakahi uila-type kali koʻu mau kaha o ka halepaahao membranes. He nui ka waiwai. Nifedipine kekahi i nā hoʻomaha o vascular ala apuupuu Muscle, mahuahuaʻike ākea a me ka coronary arteries, ka hoʻopau o spasms. Kēia ho'ēmi i kā ke koko, systemic vascular ia'ku, cardiac afterload a me myocardial ka oxygen koi. No hoi, i ka wa e lawe ia k ‰ mau i ka hōʻike 'ana i kekahi mau symptoms. Oia, aia no he hōʻemi iki emi ma myocardial contractility a me ka papa naʻau, e like me kekahi mau mea hoemi platelet aggregation.

Pharmacokinetics

Ma keia manao, "Farmadipin" (kulu), olelo ao no ka hana i noʻonoʻo pono i loko o keia palapala hoike, i kona mau ano. Ka wā i na? Eaia a pau i loko o ka digestive'āpana pono ke kemu. Kona bioavailability mea ma kahi o 40-60 pakeneka. A oi loa kokololio kūpono 'ole (ma hope o 5-10 min) ike i loko o ka manaʻo o sublingual hooponopono. He nui ka ike. Nō kāu, o ka mea nui hookoia ua ike i ka 30-40 minuke. Manaʻo o ka 'ai, inu uaʻaʻole maopopo maikaʻiʻole i ka uku o ke omo o ka Agena. I ka hoike ana o ka hemodynamic ole, e hoomau no 4-6 hola. Penei 90 pakeneka o ka nifedipine e paa ana i ke koko wai koko nā polokina. Ua metabolized ka hoʻomākaukau me "Farmadipin" (e like) i loko o ke akepaʻa. Ke alo aku o ka huinaʻae o ka nifedipine mea mai 0,4 e 0,6 L / kg / HR. Ua Ua ho oholo wae mai i ke kinoʻano nui me metabolites AEeOEXAaI type. Ke au o ka hapa-ola e ĸokoĸa ana nä pane mai ka 2 a hiki i 4 hola. I ka kūpuna a me nā mea maʻi me ka cirrhosis o ke akepaʻa, nifedipine pūnao 'aʻole hoʻi ia me ka nui loa. E like me ka hopena, ka mea i hiki ke mahuahua hapa-ola o ke anakahiʻano o ka hola 2-pa. Ma keia hihia ia mea e pono e emi i ka mahele lāʻau, a hoonui i ka wā mawaena ma waena o? Eaia o ka olelo mai hoʻomanaʻo. Nifedipinv kino ua ole cumulated. Nō hoʻi ia i loko o ka liʻiliʻi nui ke komo iloko o ke koko-lolo a me ka placental ke'ākeʻakeʻa mai. Ma keia hihia, ka mea, ua excreted ma ka umauma o ka waiu.

nāʻikepili

I kauoha mai ai "Farmadipin" (e like) i loko o ka kēia hihia.

• Ma ka hanana o ka nui hypertension a me ka symptomatic.
• No ka lapaau a me ka Kāohi stenokardicheskie ho'āhewa wale.
• I ka hypertrophic cardiomyopathy.
• A lohe o Raynaud ka maʻi.

palapala noi

E "Farmadipin" (kulu) sublingually. A hiki i ka lae ala hou mai i loko o ke koko, (e laʻa me, 180 / 100-190 / 110 mm o V. Hg.), A hookahi loiloi mua mahele lāʻau o ka lāʻau no ka makua nui o ka hola 3-5 kulu (2-3,35 mg). Nā mea maʻi me ka holomua makahiki ua no hoi ia i ka maopopo laʻau heluna. O - i hou aku 3 kulu (ma kahi o 2 mg). Nō hoʻi, i ka hoakaka helu ke drip ma luna o kekahi apana o ka berena maloo paha kōpaʻa. Kona hoomanawanui, e paa i ka wa e hiki i loko o ka waha. Me ka lawa kūpono laʻau heluna o ka lāʻau ua mahuahua ke kiʻekiʻe a lapaʻau hopenaʻoi loa. Ma keia hihia, ka mea a pau hilinaʻi nui ma luna o ke kanaka. Ma mahope hoikeana mahuahua i loko o ke koko, E ke alakaʻi kaʻoi loa i ka ahaaina i mahele lāʻau. Nō hoʻi, he mea kekahi maopopo ana. , Ae waiho nei ma ka mea i ina i ke koko, ku ae la a hiki i 190 / 100-220 / 110 mm o Hg. v., alaila, e lawe i ka lāʻau paka ua hiki ke i nā mahuahua ia 10-15 (6,7-10 mg). Ka mea, e lawe i ka mooolelo o ka hoʻololi ma ka puʻe i loko o ka hāʻawi 'Isaaka. He nui ka ike.

Pono no hoi e lawe i ka mooolelo o ka alo o ka mahuahua pā lonoaʻili i loko o kekahi hoʻomanawanui iki mai a hiki i kēia lāʻau 'like "Farmadipin" (kulu), a hōʻike manaʻo i maikaʻi. Ma na hihia a pau, i ka laʻau heluna ua koho pākahi. E hoʻomaka me 3 paka ua, a laila, i nā hoala i 2-3 (1,34-2 mg) a hiki i ka manawa i ka wa a ka makemake lapaʻau hopena ua loaʻa.

Ua hoʻomanaʻoʻia ai ia ia ma ka oi o ka loiloi mua mahele lāʻau o ka lāʻau hiki i ka pahikakiwi oi emi i loko o ke koko,!

ʻaoʻao kanawai

Ma ka noi o keia hoʻomākaukau like "Farmadipin" (kulu o ka puʻe), loaʻa paha e symptoms o nausea, tachycardia, hypotension, "iʻa" o ke koko a hiki i ka maka. Ma kekahi mau hihia, e i allergic reactions i loko o ka palapala o ka'ūhā edema, ili wikiwiki. Ka mea, ke i ho'āʻo symptoms o ka nawaliwali, pōniuniu, headache.

Contraindications

Ke? Eaia o ia i ka lāʻau ', like me ka "Farmadipin" (kulu) ua papaia e lawe i ke alo o ka mahuahua pā lonoaʻili i kona eiiiiiaiou, cardiogenic kŰia, loa aortic a me mitral stenosis, hypotension, tachycardia, e like me i hāpai keiki, a lactation.

overdose

Ma ka keia hihia, kekahi o ka hopena maikaʻi symptoms ke kānāwai. O overdosing na ai 'like "Farmadipin" (kulu), hiki ke ukali ma ka hanana o ka naau e loaa, kŰia, metabolic acidosis a me convulsions, he nihinihi haule i loko o ke koko,. A hiki i ka hoike ana o kēia mau symptoms mea pono e akoakoa ai i kekahi mau manaʻo ana o ke kōkua. Ka mea, he poe i loko o gastric lavage, ho'ā 'kalapona, kalipuna koloriside a me ka hoʻokomo' ia 'sympathomimetics, symptomatic Inc.

hoʻohana Hiʻona

"Farmadipin" (kulu o ka puʻe) a pani no ka mea, e e hoopili wale nō me ka manao lapaʻau ka mālamaʻana o ka poʻeʻelemākule nā mea maʻi a me nā mea maʻi i loaʻa:

- lolelua ka angina.

- loa naʻau ole.

- hypertrophic cardiomyopathy.

- huʻi aortic stenosis.

- loa pulmonary hypertension.

- huʻi hahau ana.

- mimikō mellitus.

-ʻaʻa puʻuwai kuleana pili i a me ka akepaʻa.

Ka laʻau heluna o na laau i hoʻohana i ka nifedipine E e waiho pākahi. Cardiac glycosides i hiki ke hoʻohana i? Eaia o ia ka lapaʻauʻia me "Farmadipin" (kulu), analogs a i hoikeia ma lalo nei i loko o kēia puke.

Ma ka loaʻa 'ka mea i ka wā hoʻokahi noi o nifedipine me ka intravenous makanekiuma sulphate hapai wahine Pono e hana akahele ka mālamaʻana o ke koko,. Kēia i hanaʻia no ka mea, aia no he manawa kūpono o ka hakumakuma ke koko, pilikia i hiki nā makuwahine a me ka fetus.

Nā mea maʻi me kaʻole hepatic functionality, no hoi he pono akahele ka mālamaʻana. I loa hoopii, e hoemiia ka mahele lāʻau e.

Nifedipine tsitohromichnuyu metabolized Via ka P450 3A4 nenoaiu. E like me ka hopena, ai 'e inhibit a induce i ka hoakaka ia wahi'ūhū e hoololi i ke kanawai o "ka loiloi mua EYI" a me kaʻae o ka waiwai. Inā concomitant ana o ka nifedipine me ka ai 'o kēia' ano E e hoi malalo o ke koko,. Inā pono, e, Kamuela i kekahi ka ho'ēmiʻana i loko o ka laʻau heluna o ka lāʻau ', like "Farmadipin" (kulu).

E mālama nei i hoʻokaʻawale ia mea i loko o lūmaua ua hoikeia mai i ka pilina ma waena o ka hoʻohana 'ana o ke kalipuna hakaka ma keia hihia nifedipine a biochemical inverse spermatozoa mea hou i ka mea hōʻemi o ka hiki ana o ka mea hope, e hoʻokō fertilization.

Lawe "Farmadipin" (kulu), ka mea e hoomanawanui, mai hana palena papaha hoʻopōʻino type, e noi ana i oi aku noonoo. Oia, ia ia mea,ʻaʻole e pono ke kipaku kaa, a hana i nā maomeka, a no laila, ma luna o.

AaOIeIOUIeXAOAaIN

"Farmadipin" (droplet) mai ka hypotensive hana. Kēia hiʻona hoʻokāʻoi aʻe ana i ka ai 'mai ka waeʻano blockers. Ia mea, "Farmadipin" (kulu) maoli he β-adrenergic loa, diuretics, nitrates, a me nā antihypertensive hope, hoomakaukau iho a me nā mea inu i loaʻa ka waiʻona, tricyclic antidepressants. Ma kekahi mau hihia, nifedipine ho'ēmi i kā ka quinidine lehulehu i loko o ke koko wai koko. Akā,ʻo ke kāpaeʻana o kona nui ia maoli. Penei, ka hoʻohana 'ana i ka hoʻohui pū Inc ua waiho ia kanaka hoʻoponopono i ka pae o ka quinidine lehulehu i loko o ke koko wai koko.

"Diltiazem" ho'ēmi i kā kaʻae o ka lāʻau 'like "Farmadipin" (droplets). "Fentanyl" me ka nui loa hoʻokāʻoi aʻe ana i ka hoike ana o hypotensive hopena. E like me ka hopena, mamua i ka hooponopono ana i ka lāʻau '(ma ka emi o ka 36 hola.) La nōʻoe,? Eaia "Farmadipina". Olelo ana o ka β-blockers me nifedipine e alakai i ka hypotension. "Farmadipin" (kulu) hoonui ae i ka lehulehu o ka theophylline, carbamazepine a me digoxin i loko o ke koko. "Rifampicin" hiki aku i ka mea hoʻonāwaliwali maoli nō o ka pākōlea kanawai o ka nifedipine, pela piʻi aʻe i ka hana o kona pūnao. "Cimetidine" hoʻokāʻoi aʻe ana i lehulehu "Farmadipina" i loko o ke koko wai koko.

Terms a me na kumu o ka pūnaewele

Ma keia hihia, eia kekahi mau ana hoʻohālike. Store "Farmadipin" (kulu) pono ia i mehana ea i loko o ka wahi maloʻo. Ke k Pono e palekana mai ka malamalama, a me ka loaa ole o ke keiki. Waho pūnaewele o keia k ua papahana no ka mai ai i 1 makahiki a me 6 malama. Once wehe i ka hue - 28 lā.

aiiia

"Farmadipin" (kulu) hiki ke hoʻomaopopo wale ma kuhikuhi.

hāʻawe

Ma ehiku huewai o 25 ml a me 5 ml. Ka mea, ua hoʻopuka kālā i loko o ka pack.

"Farmadipin" (kulu) analogues ma Rusia

He nui ae pani ai no ka waiʻona. I ka papa kuhikuhiE poʻe i:

- "cordipin".

- "Nifedipine".

- "Adalat".

- "Kordafleks".

- "Corinfar Uno".

- "Kordafleks RD".

- "fenigidin".

- "Osmo-Adalat".

- "cordipin retard."

- "cordipin XL".

ka hopena

Ano, ia oe i ka mea a ka mea like "Farmadipin" (e like) i ka lapaau, mai i ka mea kōkua a me ka mea waiwai. Ma kekahi hihia, ma mua ka lawe ia k ‰ E nīnau aku i ka palapala hōʻoia no kauka.