Ka lāʻau "Avastin": ahonui e hoike, aʻo no ka hoʻohana 'ana,ʻaoʻao' ole

Ka lāʻau "Avastin" Ua noʻonoʻo pono i ka antitumor konohiki, a pili ia i monoclonal nā mea'aʻaʻa. Ma ke noi o ka lāʻau mea he emi Holomua o metastatic maʻi a me ka microvascular permeability ma malignant hikoko o nāʻano likeʻole, pakahi aku la ia ka poe e pili ana i ka wahine umauma, AeXIeAaOIePEAaI, a me ka pancreas a me ka prostate.

i ka lāʻau

Available lāʻau "Avastin" i loko o ka palapala o ke kiaʻana i kāna i ua manao ia e hoomakaukau i ka pāʻoihana no infusion i e colorless paha iki brownish perceptible.

Ke kumu o lāʻau waiwai ka bevacizumab. Ke koʻi lipi ma Ua loaʻa i loko o pūʻolo helu o 100 mg, a me 4 ml oʻeleu waiwai a me ka 400 mg / 16 ml.

Pharmacological 'ole

"Avastin" - kuʻeho lāʻau e inhibits ke kahua o ka hou moku koko e haawi mai i oxygen, a māhuaola i nā'aʻaʻa neoplasms, a ilaila e leie hoolilo o kaʻano pākīkē Ka maʻi 'aʻai i loko o ka maʻi ke kahua. "Avastin" (pane o nā mea maʻi, a kauka - maopopo) hana overwhelmingly i loko o ka metastasis o nā malignant hikoko.

No keia mea paahana ua wehewehe aku ma ka ka palena haʻahaʻa nui o ka laha ana ma ke kino, ma ka hou, ia mea lōʻihi lawa ka wehe 'ia mai ke kino, a e leie aku e malama i ke koi' ia dala o ke kumu nui ke keʻena o ka lāʻau ma ka injecting mea pololei e like me ka olelo - koke aku i 14-20 lā. Loko lāʻau lapaʻau huahana mea,ʻaʻole i loko o ke akepaʻa a me nā konāhua, a ma nā mea a pau keena o ke kino no 18 lā no nā kānaka, a no ka wahine - 20.

Akā, ua maikai "Avastin"? E hoike aku nei au i keia mea he loa ka hoʻokō lāʻau, ina e hui pu iho la ia me ka chemotherapy i loko o nāʻano o ka maʻi 'aʻai. Kēia 'o ia hoʻi nunui maoli ke ola au o nā mea maʻi i loko o nā pūʻulu, a me ka Holomua o ka maʻi ia lŘlŘ.

"Avastin": nāʻikepili no ka hoʻohana

Kēia lāʻau ua hoʻomano hoʻohana 'ia i loko o Ka maʻi' aʻai Inc. Kauka i koi 'ia:

1. Ma metastatic colorectal Ka maʻi 'aʻai. Ka lāʻau 'Ua pono no ka hoʻohana i ka huipūʻana me ka chemotherapy ma muli o' fluoropyrimidine '.
2. Ma metastatic umauma Ka maʻi 'aʻai. Ua Ua hoʻohana 'ia me ka laina mua o ka hana maikaʻi i loko o ka huipūʻana me ka "paclitaxel".
3. I ka inoperable, pu ma ka helu nui o metastases a neplosko-, ole-liilii, ke kelepona hele akemāmā Ka maʻi 'aʻai - like me ka mua laina Inc ma ka hui pu ana, me ka chemotherapy platinum ma muli lāʻau lapaʻau hoomakaukau.
4. I ka holomua 'ole metastatic Ka maʻi' aʻai, me ka hoohuoi ana hakuʻala keena - me he Agena no iniiaiie Inc i loko o ka huipūʻana me "Interferon Alpha-2a".
5. I ka glioblastoma i loko o ka huipūʻana me ka pāhawewe Inc, a 'temozolomide' i loko o nā mea maʻi i ka lānai hou diagnosed, ma ka monotherapy a me ka huipūʻana me "irinotecan" i loko o nā mea maʻi me ka recurrent glioblastoma a me ka maʻi 'aʻai Holomua.
6. E hoomanawanui i ka poe i diagnosed me "malignantʻeho o ka wahine wahine mutilation", a ma iniiaiie peritoneal Ka maʻi 'aʻai. Ma keia hihia ka mea, ua waiho, e hāʻawi aku i ka lāʻau "Avastin" e like me ka mea mua 'inikua Inc i loko o ka huipūʻana me "carboplatin" a me ka "paclitaxel".

Eia kekahi, he lāʻau lawelawe me "carboplatin" a me ka "Gemcitabine" i haawiia mai no ka holomua maʻi paha ikepili koʻikoʻi i platinum-ma muli konohiki, e hoʻomanawanui iki mai me ka maʻi 'aʻai o ka wahine wahine nā loko a me ka peritoneum, i i ole, ua hanaʻia e ka mea paahana, a me kekahi ano o ka inhibitor o VEGF.

Pehea e komo "Avastin"?

"Avastin" (pane o nā mea maʻi a me na kumu e hooiaio ia) - he maikai lāʻau, akā, e pono e pono ai; lawelawe iho, a ma lalo o ka hooponopono ana o kauka wale. Ua Ua pololei papaia e komo i ka mokulele hēkī - wale intravenously, a laila, e like me ka lohi e like me ka hiki. Ke i ka ho omaulia He 5 mg no 1 kg o ke kino kaumaha 1 manawa i loko o nā pule.

Na koi nui o ke kiaʻana i kāna ua nāu kekahi i loko o 100 ml 0,9% paʻakai koloriside. Ka mahele lāʻau mua ua paipaiʻia e komo i kekahi a me ka hapalua hola ma hope o chemotherapy, hou ka pahu kui o "Avastin" ua hana mua ma hope o ka kaʻina hana paha. Inā ka mua hooponopono o ka lāʻau i ka hoʻomanawanui i ole complications, o ka oi ia hiki ke lawelawe i loko o ka hora, a me nā mea a pau mahope injections - no ka hapalua o ka hora, akā, wale ina o ka lua o ka ua, ua hoolilo maʻi oioi pono.

O mahele lāʻau ua i waiho e emi i ke alo o undesirable loa, ina e pono ai, ke wehe 'ia a hele aku i ka iapaau ana.

Inā ka hoʻomanawanui i ua 'akomi i metastatic colorectal Ka maʻi' aʻai, ka paipaiʻia ka loiloi mua mahele lāʻau o ka 5 mg no kg kino ke kaupaonaʻana, hoʻokahi nō kela 14 lā a 7,5 mg / kg, akā, ma hope o kēlā 21 lā. Inā o ka lua o ka laina Inc, ua mahuahua ka 2 manawa i ka laʻau heluna.

Inā diagnosed me ka maʻi 'aʻai o ka umauma i ka wahine, ma keia hihia, o ka mua ka pahu kui ua waiho ia ka hoʻomanaʻo o 10 mg / kg, a ke lawe mai i ka pahu kui kela mau pule. A ekolu, akā, i loko o keia hihia ka mea, ua lawe ia 15 mg no kg kino ke kaumaha.

Inā he mau hoailona o ka Holomua o ka maʻi, lapaʻau e e hoʻi i kāpiliʻia.

Me he ākea inoperable, recurrent, a metastatic neplosko- ai 'ole-liilii, ke kelepona hele akemāmā Ka maʻi' aʻai ma ka iapaau ana ua lawe mai i loko o ka huipūʻana me ka chemotherapy ai 'Pt (i oi aku 6 pōʻaiapuni), a ma hope o ia i ka lāʻau' hoʻohana like monotherapy.

oe pono e hooki aku i ke komo "Avastin" A e ike i na hoailona o ka maʻi 'aʻai Holomua. Na Ke Kumu no ka hoʻohana Hawaii ina ole Holomua, i ka i ka ho omaulia mea 7,5 mg / kg kela 14 lā a ua hoomahuahua ia ka laʻau heluna ma ka hapalua, a ua lawelawe koke iho o kela mea keia ekolu pule ma ka hou ana i ka "cisplatin" a me ka "carboplatin".

I kaʻaʻa puʻuwai aeea Ka maʻi 'aʻai mahele lāʻau e ole oi aku mamua o 10 mg / kg no 15 lā hookahi. Inā he mau hoailona o ka Holomua o ka maʻi, i ka iapaau ana e e hoʻi i kāpiliʻia.

Mua kanaka e,ʻaʻole pono e hoʻomaʻa i ka mahele lāʻau.

"Avastin": overdose

Uluwehi O overdose ia lŘlŘ loa pinepine ia i loko o ka hanana i ka hoomanawanui i hoʻohikiʻia kiʻekiʻe mahele lāʻau - 20 mg no kg hoʻomanawanui kino ke kaupaonaʻana i nā 14 lā.

Ma keia hihia, e hana migraine ho'āhewa wale i loko o ka 'ano luna' palapala, ma ka hou, aia ua ua mahuahua adverse loa i wehewehe 'ia ma lalo nei. Special antidote hakuʻole, wale symptomatic Inc ua hoʻohana 'ia.

"Avastin":ʻaoʻao loa

"Avastin" - He loa maikai lāʻau, i loko o ka hapanui manawa mea kōkua i ka 'ūlōlohi i ka Holomua o ka mea maʻi, akā, ua undesirable' ole mālama pinepine nā mea maʻi. Ma pohihihi keia hoopii, ka mea hiki e he nui:

1. Perforation o ka'ōpū a me ka naʻau liʻiliʻi.
2. Kūloko kahe ana ke koko.
3. Arterial thromboembolism.
4. Hoʻonuiʻia ke koko, a me ka proteinuria e hoʻomōhala ai. Loa paha, keia mea heʻilihune o ka hoʻomanawanui mahele lāʻau pane.

Eia hou, e hoomanawanui i ka poe i hoonohoiaʻi lāʻau "Avastin",ʻaoʻao 'ole a me nā symptoms hōʻike:

• hohonu aa koko thrombosis, he luna 'ano o ka naau e loaa, supraventricular tachycardia, kahe ana ke koko;
• leukopenia, neutropenia, haʻahaʻa hemoglobin thrombocytopenia;
• discomfort i loko o ka peritoneum, opu kāna hana, ke koko i loko o ka noho, he lele poʻe noʻonoʻoʻole i loko o ka waha, kahe ana ke koko nui aʻe ana, na naau oʻu iaʻi;
• kahe ana ke koko mai ka ihu, muli o ka oxygen, pulmonary thromboembolism;
• maloo ili, dermatitis, ili leo;
• lilo o ke ono, kokololio kaumaha poho, syncope, migraine, hahauʻana, drowsiness;
• blurred hihiʻo;
• eha ma ka wahi ma ke medicament ua lawelaweia ana;
• kahe ana ke koko mai ka uterus, urinary'āpana maʻiʻaʻai, he ano o ka luhi, dehydration.

Contraindications

Ina paha e makemake a pau kūpono "Avastin"? E hoike aku nei au i keia mea he maikai lāʻau, akā, aole nae ia i ua contraindications i ka pomaikai, a me ma mua oe hoʻomaka lapaʻau, pono e hai aku ia oe i ke kauka no ia. Ka lāʻau 'E ole e hoakaka ia ma ke kēia hihia.

• ina he mea kekahi kūikawā intolerance ka papa kuhikuhiEʻeleu 'Oponopono;
• Aia i infectious maʻi o ka maka a me ka periocular wahi;
• i hoʻomaka ai Intraocular li nui;
• makahiki o nā makahiki 18;
• Hāpai keiki, a lactation.

Eia hou, ina o ka hoʻomanawanui i ka manawa o ka hahauʻana, a laila lākou i meaʻoiʻoi "Avastin" i wale nō ma hope o ka hoʻomanawanui akahele ninaninau, a hele mai i ka hopena i ka lāʻau pono.

Cautions

Malama ia no elike lāʻau e wale nō kauka O ka mea e hoao ana e lawelawe mai intraocular injections.

Ma hope o ka mea paahana i hoʻolauna, oiai ka mea, ua i pono e loaʻa mai ma hope o ka huila o ke kaʻa, a hana i ka hana pili i na maomeka a pau, no ka mea e hoʻomōhala transient pilikia makapō ka haunaele.

"Avastin" (ka Hookah ua hōʻike ma ka olelo) pono wale e waiho i loko o ka Pahu Hau, oiai ma kekahi hihia mea pono ole e paʻahau. Ua Hooia e kuhikuhi wale.

Pehea e launa pū ' "Avastin" me nā ai'?

Uluwehi O "Avastin" Ua incompatible me dextrose pāʻoihana. Nō hoʻi, i ka lāʻau e hoonui i ka pilikia o adverse reactions wā ia i loko o ka huipūʻana me ia mau mea:

• "Sunitinib malate" - kānāwai hoʻomōhala microangiopathic hemolytic anaemia;
• platinum a taxanes - hiki complications o infectious pathologies, loa neutropenia, mahuahua pilikia o ka make;
• "Panitumumab" a me ka "Cetuximab" - maoli kaʻawahia ole o ka ai ', a hiki aku i ka make.

"Avastin" ma ka ophthalmology

Loa nei, i ka ike iʻikeʻia i loko o ka ahakanaka i ka lāʻau "Avastin" hoʻohana 'ia e ophthalmologists, e hana lakou i na mai o ka maka, a haawi loa maikai hopena. Akā, ka mea? He aha kēia mai nei e pili ana i ka Hookah? Ua kēia mea paahana e leie aku oe e hooki ole wale i ka ulu o ka hikoko, akā, no hoi e hoola i na mai o ka hihio?

Ae, i ka mea loaʻa ka 'ike i ka ua lohe kekahi nā mea maʻi e pili ana i ka pomaikai o ka lāʻau a hiki i ka maka, a me kaʻaʻa i ka hana i ka pana "Avastin" i loko o ka vitreous, akā, i nā hualoaʻa, he disastrous. Ka lāʻau 'ka mea, i ole lawe mai i kekahi e olaʻi, ma ka mea ku ole, alakai aku ai i ka mea i kanaka e pono makapo. "Roche" poe i pinepine ae la oia 'aloʻahia i "Avastin" hiki ole ke hoohanaia ma ka ophthalmology, kona manaʻo mea okoa.

Ka lāʻau 'Ua manao ia e emi ai ka nui o ka ulu ana o na moku koko e hooluolu iho i ka maʻi' aʻai, pela i ka ho'ēmiʻana i loko oʻeho ulu pinepine '. I mea no ke aha la mua e hoʻomaka Inc, a hoolohe unsubstantiated koi maikaʻi, e nīnau aku i ke kauka.

"Avastin": counterparts

Like no ina paha he nui ae pani, a makemake i loko o kona haku mele 'ana o ka ia kumu waiwai, ka mea aole i hana ia "Avastin". Analogs o keʻano papa hana o ka hana i, a me ka mea hoi e maikai i nā hualoaʻa ma ka meheu o ia i ka ulu ana o na moku koko, a me ka hooulu ana o cancerous hikoko. Mau nā:

• "Arzerru".
• "Campath".
• "Rituximab".
• "MabThera" ¶ AL.

Akā, e pono e hoomanao i ke kauka mai, e koho i mea like.

"Avastin": pane o nā mea maʻi, a lapaau

"Avastin" (manual Ua hoʻopaʻa) o ka wale lāʻau i kekahi i loko o kona haku mele 'ana bevacizumab, e kōkua i ka' ūlōlohi i ka ulu ana o na moku koko ana i kaʻeho, i laila ka meheu o ia i ka maʻi Holomua. Ka hapa nui o na kauka i malama i keʻano o ka maʻi i loko o ka ua hoomanawanui, e olelo ka mea, i loko o ka mau o ka injections noticeably ka meheu oʻeho ka ulu, i ka papa kuhikuhiE mea - i ka pono, e lawe i ka lāʻau a me ka mai e hui pu iho la ia me ka ai 'ana ma ka hui pu ana, hiki i ino nui i ka hoʻomanawanui.

Hōʻuluʻulu i, ua hiki ke olelo aku i kaʻoiaʻiʻo i "Avastin" (ka hoʻohua - F. Hoffmann-La Roche) - he maikai, a kokua hooloihi i ke ola o nā mea maʻi me ka cancerous hikoko. Akā, i ka mea e pono ai wale, e pili ia ma lalo o ka ikaika nā limahana o ke kauka, ai ole i ka hopena hiki e irreversible a pau inoino.