Ka loina o ka complementarity: ka pā like o ka manaʻo, a me ka walaʻauʻana kānāwai o aaiaoe?

Complementarity - keia waiwai i mau hale hoʻopili like i kekahi i kekahi ma ka hana alanui.

complementarity rula loaa palapala noi i loko o kekahi mau spheres o kanaka haʻawina. No laila, i ka i loko o ka complementarity i loko o ke aʻo kaʻina hana a hiki i ka kiko'ī ano o ke kahua, a kūpono 'ana o nā haumāna i loko o nā kūlana o ke kumuhana o ke kula' ole. Ma o ka wahi o kaʻike hoʻokumu i ka haku mele ka mea, ua pili i kuhikuhina, a ma ka kemikaʻeleu rula o ka like māhele nā hale o nā okoa nā lātoma, i kānāwai ma waena o ka hydrogen ka ponaʻana a me ka intermolecular AaOIeIOUIeXAOAaIN.

ka loina o ka complementarity ma kālaimeaola pili ana i ka kaʻaeʻana o ka biopolymer nā lātoma a me kā lākou kekahi mau koena ai. Ka mea, e hōʻoiaʻiʻo i ke kahua o ka definite pilina ma waena o ia (e laʻa me, hydrophobic a electrostatic hana kūleʻa ma waena o ka mea i hoopiiia iaea ooieoeiiaeuiiai pūʻulu).

Penei mea manuahi koena ai a me ka hoopaaia e biopolymers ole covalent Nine Inch mea paa a me ka māhele palapala i kekahi i kekahi, e lilo nawaliwali nā loulou i collectively i ke kiʻekiʻe ikehu, i kumu no ka ho okumu ana o ka pono i ka pilina paʻa pono o nā lātoma. Ma keia hihia, no ka catalytic hana o ka waiwai i kalele iho ma luna o lākou complementarity me ka waena catalytic reactions.

Au pono aku nei au ia he mea no hoi i ka manaʻo o mall palapala o na hui elua. No ka mea he nui, i ka wa a ka intermolecular AaOIeIOUIeXAOAaIN o ke kumuʻiʻo complementarity rula - i ka manawa kūpono o ka ligand hoʻokokoke kekahi i kekahi i ka pili kaawale e hoʻolako i ka ikaika pilina ma waena o lākou.

I ka rula o ka complementarity i loko o ka mahinaʻai o aaiaoe pili replication (a pāpālua hoʻi) o ka DNA. Kēlā me kēia kaula o ka 'ole ke malama me ka EOIeIOUIeXAOOON i ua hoʻohana' ia i loko o ka hoʻololi kemikala o ka mea manuahi kaula makalii i ka hope loa ke kahua e leie aku e loaa replicas o ka palapala deoxyribonucleicʻakika. I ka Ia manawa, aia no he maopopo palapala ma waena o ka nitrogenous kumu, kahi adenine e hoopaa ana i ka thymine, a me ka guanine - me ka cytosine wale.

Oligo a polynucleotides nitrogenous kumu i hana i ka AYEIE mau pono a pau o - T-A (A-U ma RNA) a D-C ma ka reacting mau kaula makalii o nukelea nāʻakika. Radio kēia rula o ka complementarity i ki kūlana ma ka hōʻoia 'i ke kahua kaʻina hana o ka pūnaewele a me ka hoolilo ana o aaiaoe' ike. Penei, a pāpālua hoʻi o ka DNA i ke kelepona hele mahele, ka DNA i loko o ka RNA Ekolu a kaʻina hana i ka lawe wahi i ka wa a ke kumuʻiʻo hoʻololi kemikala a me ka hoʻoponopono 'keʻano o ka hanaʻana (ka ho'ēmiʻana) o ka DNA poino ma hope, ua hiki ole me kaʻaeʻana i kēia rula.

Wā kekahi paewaewa ma ka pololei hoʻoholo ma mua palapala ma waena o nui māhele o okoa nā lātoma i loko o ke kino a me ka pathology i ua clinically hoikeia aaiaoe maʻi. Ka mea hiki ke pū i hiki i ka poʻe mamo a e incompatible me ke ola.

- Eia hou, nui ka Ka Ikepili ua muli ma luna o ka loina hooponopono o komplementaranosti PCR (polymerase kaula naoh). Me ka hana i ho'ākāka 'aaiaoe detectors huai ae DNA a RNA o kekahi mau pathogens a infectious mea hoʻomaʻi illnesses i loko o ke kanaka, a kokua i hoakaka ia iapaau ana, e like me lesion etiology.