'O ka Hyperandrogenia i loko o nā wāhine: ke kumu, nā hō'ailona, ka ma'i. He aha ka waiwai giperandrogenia i loko o nā wāhine

I loko o nā lā'au lapa'au, ua'ike'ia kekahi'ano pilikia e like me ka hyperandrogenism i nā wāhine. 'O nā kumu, nā hō'ailona, nā ma'i me kēia'ikepili e pono ai ka ho'ona'auao a me ka komo'ana o nā kauka kauka. A'oiai'o kēia ma'i he mea pa'akikī loa ka ho'okahuli'ana, e pili pono i nā kauka me ka ho'oka'ulua'ole.

Ke kumu o ka ma'i

I ka wa e hele mai ai i keia mai e like me hyperandrogenism i loko o nā wāhine, ke kumu symptoms, lapaau a me ka kāohi ana i mau pili me ka pilikia kekahi, e like me ka hopena ma luna o ke kino adrogenov. 'O kēia ka'ina hana e alaka'i i ka hi'ohi'ona i ka hi'ohi'ona wahine o nā'ano kāne a me nā loli maika'i'ole. Ke'ōlelo nei mākou i nā mea kiko'ī, ke kama'ilio nei mākou i nā'ano hō'ike e like me ke'ano o nā mea ulu ma ka helehelena a me ke kino, ka leo ha'aha'a, a me nā ho'ololi'ana i kekahi mau'ano o ke ki'i.

Pono e ho'omaopopo'ia he'ano ma'amau kēia'ano pilikino o ka pūnaewele endocrine wahine, a'a'ole hiki iā ia ke alaka'i wale aku i nā loli o waho, akā no ka ho'okau'ana i ka'ike'ole. No laila, inā loa'a iā'oe nā hō'ailona mua o hyperandrogenism, pono'oe e ho'onohonoho koke i kahi kipa i ke kauka.

No ke aha i ulu ai nā pilikino?

'O ke kumuhana o "hyperandrogenism i nā wāhine: ke kumu o nā hō'ailona, ka ma'i" He mea nui i nā wāhine, no ka mea, ua'ike'ia kēia pilikia ma kahi o 20% o nā ma'i. No laila, he mea kūpono ke ho'olohe i kēlā mau mea a me nā hana e hiki ai ke ulu'ana i kēia ma'i.

Ma ke'ano kumu nui, hiki ke ho'omaopopo i ka ACS - ad syndogenital syndrome. 'O ka lālani lalo,'o ia ka mea hiki ke hana i nā'elemona he nui wale, me nā mea e pili ana, e like me ke'ano, glucocorticoids. Hō'ike'ia ka hopena ma lalo o ka mana o kekahi enzyme. 'O ke kumu no ka hopena o lākou ka hō'ili'ili'ana i nā androgens. I kekahi manawa, he hapa o ka enzyme kahi wahine i hānau ma hope, no laila'a'ole i loli'ia nā homone kāne, akā e ho'onui mau loa'ia, e ho'ololi ai i ka ho'ololi'ole i ke kino wahine.

Aia kekahi hana'ē a'e, no laila e ulu ai ka hyperandrogenia o ka adrenal genesis. Ke'ōlelo nei mākou e pili ana i nā ma'i koko o nā'ōpū. Ua hana'ia ho'i lākou e kū'ē i ke kūlana o ka ho'onui'ia o ka nui o nā androgens.

'O ke kumu o ka ho'omohala'ana i nā ma'i pilikino i'ōlelo'ia ma luna nei i loko o ke ka'ina inā loa'a ka hormones male i nā ovaries o kahi wahine. Eia kekahi,'o nā pūnaewele e hua'i i nā kumuhana hiki ke hana i nā ma'i koko i loko o nā ovaries.

'O ka ma'i o ka hyperandrogenism ka hopena o nā hopena o nā ma'i o nā mea e like me ke'ano o ka ma'i, e like me ke'ano pituitary gland.

Nā hō'ailona o ka nui a me nā mea nui

Inā mākou e kama'ilio e pili ana i nā ma'i hō'ailona o ka ho'onui'ia'ana o ka hormone male, hiki iā lākou ke hō'ike'ia penei:

• 'Akea;
• 'O ka lauoho lauoho a me nā pale palū ma ka lae mua (adrogenic alopecia);

• Ho'omaka ka'āpana o ka'ōlohelohe e ho'onui i ka nui o ka'ikepili, a ma muli o ka hopena o ka momona o ka'ili;
• 'O Barifony,'o ia ho'i ka ho'oha'aha'a i ka leo o ka leo;
• Aia ma ka'ōpū a me ka umauma ka lauoho.

He mea pono e ho'omaopopo i ka'oia'i'o o ka hirsutism - ka ulu nui o ka lauoho po'ohiwi i ka'ōpū wahine, ua'ike'ia he 80% o nā ma'i me ka pilikia e like me ka ma'i hyperandrogenism.

Me ia i ka maʻi i loko o kekahi o ka maikai ke keka hiki hoʻohuikau o ka menstrual kalapona, i ka piha kaawale o ka menstruation, e like me myocardial hypertrophy, obesity, infertility, a me ka hypertension.

I ka lehulehu o kane hormones hiki i amplification o ka wahine kino susceptibility i nā mea palahēhē o acee? Iuo oeiia. Loa'a i ka luhi ikaika a me ka hihia o ke kaumaha.

'O nā'eha a me nā momona

E ho'omaopopo pono i ke'ano o ka pilikia e like me ka hyperandrogenism i loko o nā wāhine, pono e no'ono'o pono'ia nā kumu, nā hō'ailona, nā ma'i a me nā hō'ailona. Ma muli o ka no'ono'o nui'ia'ana o nā kumu no ka ulu'ana o kēia ma'i, he mea kūpono ke nānā'ana i nā hi'ohi'ona o ka hō'ailona.

Inā ho'opa'i'oe i kahi pilikia e like me ka'eha, pono e'ike'oe he kumu o ke keratini'i o ka paia o ka manu me ka ho'onui'ana i ka hana'ana o sebum, i ho'oulu'ia e ka ha'ina o ka androgens, me ka plasma. Me nā hō'ailona, e like me ke'ano, ua kauoha'ia nā COC, a me nā anti-arogens, i mea e hiki ai ke ho'omaika'i maika'i i ka ma'i o ka mea ma'i.

Eia kekahi, ma lalo o ka mana o nā hormones o nā kāne ma nā hālā o ka androgeneke, ka pua'ale'a, ka'ele'ele, a me ka lauoho lauoho ma kahi o nā pū. 'O ka hana ma'amau i ka wā'ōpio. I kēia'ano, he mea li'ili'i ka hopena o ka honeeneene e pili ana i ka makamaka, ka maka, ke kino a me ka'ao'ao.

'O ka hyperandrogenism adrenal

He mea kūpono e ho'omana'o mai i nā'ale'a'ele'ale'a he mau'ale'a'eke'eke'elua ma luna o nā pu'upa'a.

'O lākou ke kumu o 95% o ka mea i hana'ia a merogen (DEA-sulfate). 'O ka pa'akikī o ka hyperandrogenism e pili ana i kēia mau momona ua ho'emi'ia i ka'oia'i'o o ka ma'i pilikino he'ano pono'ole a mana'o ia e pili ana i ke'ano o ka ma'i Androgenital. Lawe ia i ka ho'oemi ko'iko'i'ana i ka kino wahine o ke ki'eki'e o nā enzymes pono no ka hana'ana o nā hormones e like me glucocorticoids.

Hō'ike'ia ka Hyperandrogenism o kahi pilikino 'O kēia kapo e hiki ai i ka ho'onui'ana i ka haunaele o nā mea pono'ē a'e - pregnenolone, progeterone, etc. Nā'ano hopena e loa'a ai ka ho'onui'ana i ka hana o ka androgen i loko o ka kino wahine.

I kekahi manawa ua'ike'ia kahi ma'i pilikino, i hana'ia e nā hulu o ke kēpau o ke kino e huna ai i ka hormone kāne. Wahi a nā'ikepili,'o kēia'ano o ka ma'i i ho'onohonoho'ia i ka hyperandrogenism āpau i ho'opa'a'ia i 30-50% o nā wāhine i loa'a ka pilikia me ka androgene.

Nā hopena ma nā ovas

Hiki i ka ho'oki'eki'e nui o nā hormones kāne ke ho'opili i ka hana a nā ovaries. I ka hapanui o nā hihia,'ike'ia kēia pilikia ma o nā'ano'elua: hypertecosis a polycystosis. He mea nui e ho'olohe i ke'ano o ka pilikia o ka ho'okumu'ana i kēia mau ma'i i nā wāhine e ho'onui i ka hana ma o nā pā'ani mana.

'O ka operaian hyperandrogenia ka hopena o ka ulu mālie o nā follicles ma lalo o ka mana o ka androgens. Ma muli o lākou ua haku'ia nā ovaries,'o ka hopena o ia'ano ka hopena o ka mea hope loa. 'O ka inoa lapa'au o kēia pilikia, he'oli'oli ma'amau.

Akā,'a'ole kēia ka pilikia a pau e pili ana i ka hyperandrogenia o ka hui ovaries. 'O ka laina lalo,'o ka hormone kāne ke kū'ana i ka mea e kū'ē ai i ka hanu'ana o ka pūnaehana haipule fibrous, e hiki ai i ka polycystosis. Ma kēia kūlana,'o ka mea maika'i,'o ka 5% wale nō o nā wāhine ke kū i kēia pilikia.

He mea kūpono ho'i e'ike'oe i kēia'ano o ka hyperandrogenism i loko o ka wahine maika'i ke kumu o ka ho'okō'ole o ka ho'onohonoho pono o ka kūlana o ka androgen. Ke hana nei kēia hana ma ke'ano hypothalamic a me ka pituitary. 'O ka hopena, ua loli ka'ikepuni hormonal.

Nā hō'ailona e pono ai kāu e ho'olohe

Aia kekahi mau hō'ailona e hō'ike ana i ke'ano o ka pilikia i ho'ākāka'ia ma luna nei. Ke'ike'ia nei he mau ma'i pilikino e like me ka hyperandrogenia o nā ovaries o ka genesis e hiki ke a'o'ia mai nā hō'ike a'e nei:

• Osteoporosis;
• Seborrhea;
• Ma ka helehelena, me ka ho'ohui i ka hakihaki, aia ka peeling a me ka mumū, kahi pa'akikī e pale i nā'ano hana cosmetology ma'amau;
• Ho'oma'o i ka ma'i;
• Ka nui;
• Ke ho'ololi'ana i ka nui o ka kino wahine - ke kāne ali'i;
• Ke leo ha'aha'a ('ike);
• 'O ka ulu'ana ma ke kino, ma ka helehelena;
• 'O ke kūkulu'ia'ana o nā'ōhule pū ma luna o ke po'o.

Eia kekahi, he nui nā hō'ailona kūikawā, e like me ka nui o ke kūmole glucose o ka toto, ke ki'eki'e o ka hanu'ana, ka emi'ana o ka palekana, a pēlā aku.

Ka nui o ka kaumaha

'O ka nui i loko o nā wāhine ke ho'oulu'ia i ka hyperternentia ovarian i hō'ike'ia a'e nei. Me kēia'ano o ka pilikino, loa'a pinepine'ia ka pi'i'ana o ka estradiol.

Ua hana nā kauka i kahi noi'i e like me ka hō'oia'ana o kēia mau'ōlelo:'o ka ki'eki'e ki'eki'e o ka hormone male a me ka estrogen e hana'ia ma lalo o kona mana, e'oi loa aku ka hopena i ka ulu'ana o ka momona e pili ana i ka'ano kāne.

'O ia mau kumuhana ke kumu o ka ho'onui'ia o ka insulin ma muli o ka ho'onui'ana i ka ho'onui'ia o ka hormone male i loko o ke kino o nā wāhine e loa'a ana i nā ma'i pilikino i hō'ike'ia ma luna nei. I kekahi mau kumu,'a'ole i ho'ohālikelike'ia nā torogens i ke kaumaha o ka wahine ma waena o ke kikowaena pūnaewele.

Nā'ano pilina

'O nā kauka me kekahi wala'au pono e kū i ka hō'ike o nā'ano hyperandrogenism. Ua ho'ākāka'ia kēia'ano ma ka'oia'i'o ma ka manawa ho'okahi aia kekahi hana kū'ino i nā hana o ke kino a me ka'oihana o ke kino.

He mea nui ka mana'o o ia koi'ana e no'ono'o i ka wā e heluhelu ai i ka hyperandrogenism weliweli i loko o nā wāhine. 'O ka'oia'i'o,'o kēia ka mea e hana ai: adrenal androgens, e ho'omau ana i nā'ale'a o ke anuanu, a pēlā e ho'onui ai i ka ki'eki'e o ka hormone male ma nā ovaries. Hana'ia kēia hana i loko o ke koko, i hiki ai i ka ho'onui'ia'ana o ka hormone luteinizing. 'O ka hopena, ho'onāukiuki i ke'ano o ka ma'i hyperandrogenic.

Hanana hui ano o ka pathology hiki e wahi i ka loa trauma, intoxication lolo a me pituitaryʻeho.

Nā diagnostics

Initially, pono e hoʻokaʻawale i ke kauka mai hyperandrogenic maʻi 'ē aʻe e ku e ia i ka mea e hoʻomōhala ana i (acromegaly, Cushing ka maʻi pale, ake maʻi a me kekahi poe e ae.). 'O ka hopena hou a'e,'o ia ka ho'oholo'ana i ka pae hormonal. Pono e hana i kēia hana ma ka'ōpū'ōpū i ke kakahiaka. Oia Ka Ikepili pono hana ekolu manawa like hormones me kiʻekiʻe androgen lehulehu ua mau hoʻololi.

Ho'omaopopo'ia ka nānā'ana i ke ki'eki'e o ka dehydroepiandrosterone,'o ka mea ki'eki'e e'ike i ka hyperandrogenism adrenal. ŸO ka mea nui ka ÿano o ketosteroids i loko o ka mimi. Inā'oi aku ka mea ma waho o ka ma'amau, pono ia ke no'ono'o i ka ulu'ana o nā ma'i.

Nā'ano hana ola

He mea ko'iko'i ka nui o ka Hyperandrogenism no ka ha'alele'ana i ke kōkua o nā kauka lapa'au. A inā mākou e hō'oia i ke'ano o ka ho'oponopono'ana, a laila hiki iā mākou ke ho'oholo e ho'ohana'ia ana i ka loa'a'ana o nā pahuhopu 4:

• Ka ho'one'e'ana i nā hō'ike ma ka'ili;
• Ka ho'olālā 'ana o ka'ane'ane;
• Ka mālama'ana no ka ulu'ole, i kumu'ia ma muli o ka hua'ōlelo;
• Ka wehewale a me ka pale'ana i nā ma'i e pili ana i ka ma'i kūlohelohe.

'O ka mea'ai no ka hyperandrogenia i loko o nā wāhine, ua kau'ia ke'ano o ka waiwai waiwai nui. I kēia hihia, he mea nui e hahai pololei i nā'ōlelo a nā kauka, inā wale nō e pili kēia'ano e hiki iā'oe ke loa'a ka hopena i makemake'ia.

'O nā ma'i i mana'o e hānau i ka pēpē, ma ka hapanui o nā hihia, ua kauoha'ia he lā'au himone, kahi hiki ke hā'awi i ka'ōwili piha.

'O nā wāhine'a'ole i ho'olālā i ka'ōpū, ua mālama'ia, e like me nā'ōlelo ho'opunipuni waha, a ma kekahi mau'ano ho'okipa nui o nā ovaries.

'O nā lā'au'alo lā'au no ka mālama'ana i ka hyperandrogenism i nā wahine, ho'ohana ikaika'ia inā'a'ole hiki i ke kino ke pale i ka ki'eki'e o ka androgen wale nō. Ke'ōlelo nei mākou e pili ana i ke'ano o "Metipred", "Dexamethasone", etc. A hiki i ke kaukōkino pili kino ke ho'omaopopo'ia inā e ho'onāukiuki'ia nā ma'i pilikino e ke kiko.

Nā hualoa'a

'O ka ho'onui ki'eki'e o ka hormone kāne i loko o ka'ōpū o ke kino,'oi a'e ia ma mua o ka pilikia nui, kahi e ulu mau ai i ka hope o nā ma'i'elahi'ole. No laila, i ka'ike'ana o nā hō'ailona mua, pono e mālama'ia ka hō'ailona a me ka mālama'ana me ka'ole.