"Agapurin": aʻo no ka hoʻohana 'ana, maoli

He aha mea i ka lāʻau "Agapurin"? Na Ke Kumu no ka hoʻohana 'ana, e ia ke hōʻike i ka iki ae la i ke kala palapala, a me ka haku mele' ana o na dala. Eia hou kekahi, i loko o kēia 'atikala oe e aʻo e pili ana i na hihia i loko i ka lāʻau ua ia wā kona hoʻohana ua pololei hookapuia, ike ia he meaʻaoʻao ona, a no laila, ma luna o.

I ka haku mele 'ana a me ke ano o ka lāʻau

Ua loaʻa i hoʻonohonoho 'inoa i loko o ka "Agapurin" ia waiʻona? "Pentoxifylline" - keia mea i kona lua o ka inoa.

Currently ka lāʻau mea i loaʻa i loko o nāʻokoʻa 'ano apau loa:

1. Biconvex papa kapa komo iā ia (keʻokeʻo) a me ka na ilipoo ame alohi. Kēia lāʻau kekahi mau i ka hana ke keʻena mea pentoxifylline a me nā waiwai (lactose monohydrate, maize pia, colloidal anhydrous ka silica i, talc a me ka makanekiuma stearate). Me ka mahalo i ka iwi, e nā kumu e like me carmellose paʻakai, mea pōaka sucrose, me ka pauka, sucrose, talc, methylparaben, titanium'okikene lua, ka silica i colloidal anhydrous a me ka laau sitima.
2. Pāʻoihana (akaka, colorless) no ka pahu kui. Kēia medicament nā pentoxifylline, paʻakai koloriside a me ka wai no ka pahu kui.

I makemake kekahi makemake e hōʻike i ka mea ana e like me ka lāʻau mea like hiki ke loaʻa ma ka hale kūʻai lāʻau lapaʻau kaulahao me "Agapurin Retard". Instruction o ka lāʻau mai nei i ia mea he Agena o ka hooloihi ae i hana. He loaʻa i loko o na papa, a i kapa komo iā ia me ka manaʻoe kūkulu ka penaʻana. Kēia ka lapaʻauʻia he pentoxifylline a me nā kumu e like me hypromellose, povidone, talc, a me ka makanekiuma stearate.

pharmacological waiwai

He aha mea i ka lāʻau "Agapurin"? Na Ke Kumu no ka ho ohana i hākālia nō i kēia Agena mea antispasmodic a me ka pili ana i ka purine pae. Ua me ka nui loa? Ienoai aa koko holo, e like me kona rheological waiwai. Ka pae'ōnaehana rula o ka mai la medicament mea i phosphodiesterase inhibition, a mahuahua ka maʻiʻo o ATP ma erythrocytes a me ka poʻe koa i loko o platelets pōkā saturation ka ikehu Loaʻaʻia me. Kēia hualoaʻa ma ka vasodilation a hakumakuma i ka huina vascular ia'ku (ʻike ākea), a me ka minuke, a hoonui mapuna leo me ka nui loli i loko o ka naʻau kōmi.

Keʻano papa hana o ka hana ana i ka lāʻau '

He aha ka keʻano papa hana o ka hoʻokō ' "Agapurin" ia waiʻona? Na Ke Kumu no ka hoʻohana haawi i exhaustive pane i kēia mea. Hope ana medicament dilate coronary arteries, a laila, mahuahua ka oxygen ma haawi i na ipu pulmonary a me ka myocardium, ia mea antianginal kanawai, a hoonui ae i oxygenation o ke koko.

It e kaulana e hoi i ka hōʻike hoʻomanaʻo hiki ke hoʻoulu i ka leo o naehana musculature, ma ka like o ka diaphragm a me ka intercostal nāʻiʻo.

I ka intravenous ka pahu kui mea hiki aku ai i ka mahuahua collateral holo, e like me ka mea i loaʻa i loko o ke koko buke e kahe ana ma ka 1-tsu-pauku. Eia hou, ua k ke kumu i ulu i loko o ka maʻiʻo o adenosine i loko o ka lolo, a loaʻa pono 'ole ma o ka bioelectrical hana o ka'emi ko kahua.

E like me ke aʻo, i mai la medicament Ua hiki ke hoemi i ka (viscosity) o ke koko, e hoomahuahua i ka elasticity o ka erythrocyteʻili lahilahi, a hoʻoikaika microcirculation me kaʻole holo.

He aha nā hiʻona i ka lapaau "Agapurin"? Na Ke Kumu no ka hoʻohana hākālia nō ia i loko o arterial occlusive maʻi (ʻike ākea)ʻeleu lāʻau hiki alakai i ka hoʻopau o ka po cramps i loko o nā bipi, i ke elongation loihi o ka hele ana a me ka eha ma ka maha.

Pharmacokinetics

Medicine "Agapurin" ua hoʻomaka koke metabolized ma ke akepaʻa. Kēia produces hana metabolites. Lākou lehulehu i loko o ke koko kekahi mau manawa ma luna ma mua o ka lehulehu o na kumu o ka waiwai.

Hoike ia ia iho imua o medicament like metabolites i loko o ka nui o ka 94%, a me ke koena - ma ka liʻiliʻi. Iloko o ka mea mua 4 hola ma hope o 'ai, inu o ka lāʻau hookuu i loko o ka nui o ka 90% o ka dosages i hoʻohana. Ma ka unmodified palapala, ka mea, ua hōʻike 'ia i loko o ka buke o ka 2%. Ua E hoi e kaulana ia, aole ia e nakinaki i kaʻeleu waiwai a me metabolites o pentoxifylline i ke koko nā polokina.

Ka wā hihia hoʻi hakuʻala kuleana pili i decelerates auaiaea metabolites. Inā ake hana abnormalities malama hooloihiia hapa-ola, a ua mahuahua bioavailability.

Uluwehi O "Agapurin" (papa): kauoha no ka hoʻohana

E like me ka pili kuhikuhi i ka medicament, ka mea pono e lawe i kekahi, a me ka ia manawa o ka lā ma hope o kaʻaiʻana i kaʻai, inu akaka ka wai. Ka lāʻau i loko o kekahi hihia ole e mama.

Ka loiloi mua laʻau heluna o ka lāʻau, he 200 mg ekolu mau manawa o ka lā. Inā ka hoʻomanawanui e ka lōʻihi hana a pau i hala aku ioeeiiaiey ilihune o ka lāʻau, a laila, hiki ke hoemi i ka hookahi mahele lāʻau pono i nā manawaʻelua, akā, mālama i ka helu o? Eaia.

O ia hoʻi, i kela la laʻau heluna e ole oi 1200 mg.

Ano, e ike ana i ka hoʻohana 'ana i ka lāʻau "Agapurin" (papa). i 'ano like loa no ka palapala noi kuhikuhi me ka, ua kīkoʻo akula hoʻokuʻu he' ike e pili ana i ka ia dosages. Naʻe, ka wā hoʻohana 'ana i ka mea hiki ke emi i ka multiplicity o? Eaia.

Na Ke Kumu no ka hoʻohanaʻana i ka pāʻoihana no ka pahu kui

Pehea e hoʻohana i ka lāʻau "Agapurin"? Papa i hoakaka ia oi pinepine ma mua o injectable pāʻoihana. Inā no kekahi kumu o ka hoʻomanawanui hiki ole lawe ku una ka lapaʻauʻia,ʻo ia hoakaka injections.

Kēia kanaka e hoomakaukau i kūʻaiʻia ma ka pāʻoihana ano no ka pahu kui hiki e lawelawe ma kekahi o na kēia mau kiʻina hana:

1. IV. Kahi o ka ampoule E e nāu kekahi i loko o 5% monakō koko pāʻoihana a ma 250-500 ml koloriside (0.9%) paʻakai koloriside. Ka lāʻau 'ai e haawiia mai lohi, i oi aku mamua o 150 ml no hora. Inā ka hoʻomanawanui tolerates ka lapaau, i ka kela la i keia mahele lāʻau 'ae' ana i hoomahuahua mai ai i mau ampoules, oa 200 mg.
2. Intramuscularly. Ka lāʻau 'Ua lawelawe ma 100 mg palua i ka lā. Ua 'aʻole i dilute kahi o ka hue.
3. Intraarterially. Lapaau o ka hoʻomanawanui e hoʻomaka me ka hooponopono ana o ka hookahi ampoule, a e e mālama '-nāu kekahi i loko o 20-50 ml o isotonic paʻakai koloriside pāʻoihana. Inā 'oe makemake i ka hooloihi ae i Inc, hiki e mahuahua ai ka mahele lāʻau i 2-3 ampoules. Ka mea, pono e nāu kekahi i 30-50 ml.

It E e kaulana i ka nānā 'ana i ka lapaau wale, a ma ka papa o ka kanaka hoʻomanawanui'ōlelo aʻo wale i ka kaʻoi loa ka nui o ka medicament hooku iho la ia.

Medicament "Agapurin": nāʻikepili no ka hoʻohana

Ma mua o ka hoʻohana 'ana i kēia ka lapaʻauʻia, oe e nīnau i kou kauka, a loaaʻi ka ikea ai. Ma hope o nā mea a pau, lapaʻau ua häʻawi wale ma lalo o kekahi mau deviations. Ka papa mākou e noʻonoʻo hou.

1. Trophic kāna hana no nā'aʻaʻa i i waho aku i ka backdrop o ka poʻeʻilihune venous ole arterial microcirculation (e like me gangrene, varicose ulcers, frostbite, a no laila, ma luna o.).
2. Circulatory kāna hana (ʻike ākea) a ua hanaʻia e like me ka hopena o ka hoʻoʻino, atherosclerotic a me ka diabetic keʻano o ka hanaʻana. ka lapaʻau like i hoakakaia no ka "intermittent" claudication, a ua kena ae la ma ka atherosclerosis, arterial occlusive maʻi, a me ka diabetic angiopathy.
3. Maʻi a me ka huʻi ischemic hahauʻana, i mea ischemic kumu. No hoi, ua hoʻohana 'ia ka lāʻau i loko o cerebral arteriosclerosis, paresthesia, angioneyropatii, Raynaud ka maʻi a me ka akrozianoz.
4. Hoʻopōʻino holo i loko o nā ipu o ka pilikia makapō nā loko (huʻi a me ka maʻi circulatory 'ole, a me ka vascular hei membranes o na maka).
5. State i kupu mai ma hope o ischemic a hemorrhagic hahau ana.
6. Kāna hana o ka waena i pepeiao vascular ka molekumu o, a i pu ma ka lohe me keia poho.

Contraindications i ka hoʻohana 'ana o

Ka wā e hiki ole hoʻohana i ka lapaʻauʻia "Agapurin"? I ka hana o keia k 'ia kēia ma lalo o ka ana ma lalo nei a me deviations:

• huʻi myocardial infarction;
• kāheaʻia coronary paha cerebral arteriosclerosis;
• kāheaʻiaʻaihue o ka naau pāpana;
• porphyria;
• kipi arterial hypotension;
• papakaukau kahe ana ke koko;
• huʻi hemorrhagic hahauʻana;
• retinal hemorrhage;
• hāpai keiki, umauma-e ai ana;
• i ka makahiki o ka makahiki 18 (palekana a me ka hopenaʻoi loa i ole, ua hookupaaia);
• hypersensitivity e pentoxifylline, a me nā kumumea mai ka pae xanthine nā mea loaʻa.

Makaala lakou hoʻohana no ka lapaʻauʻia

Me ka malama nui i ke koʻi lipi e e pili ana i nā mea maʻi i ka welelau o ka arterial hypotension, labile ke koko, naau hoʻokō 'ole' (maʻi), i ka welelau o ka hemorrhage,ʻaʻa puʻuwai a me ka hepatic insufficiency, a me kekahi i loko o ke ano hopeʻoki kino.

ʻaoʻao waiwai

He loaʻa i kekahiʻaoʻao ona mai o ka lāʻau, "Agapurin"? Maloko o na papa alakaʻi i ua hōʻike ma luna, e like me ka pono me ka pāʻoihana no ka pahu kui hiki i ka helu o adverse hopena. E mākou noonoo ia i loko o aku au mamuli.

• Digestive'ōnaehana: cholestatic hepatitis, intestinal atony, aggravation cholecystitis, maloo waha a me ka poho o kona'ōpū.
• Ko mākou hopohopo'ōnaehana: ka iini, Kanikani'āʻula, pōniuniu, cramps a me headaches.
• Koko na moku a me ka ili: hoʻokano, brittle kui, lehalehu t flushing, flushing i ka luna o ka pahu a me ka maka.
• Mea'ōnaehana mānowai koko'ōnaehana: arrhythmia, hoʻopunipuni angina, e holumua ai angina pectoris, tachycardia a me ka haahaa ke koko.
• Kino o ka hematopoiesis a me ka hemostasis'ōnaehana: thrombocytopenia, leukopenia, pancytopenia, gipofibrinogenemia mai intestinal kahe ana ke koko, opu, subcutaneous capillaries a me mucous membranes.
• Sensory nā loko: hihia hoʻi hihio a me ka scotoma.
• Allergic reactions: pruritus, urticaria, angioedema , a me ka anaphylaxis.

hihia o ka overdose

E ahaʻia ana ina kiʻekiʻe nā māhele o ka lāʻau "Agapurin" oe hoʻohana (400 mg, 600 mg, 1200 mg)? Ma keia hihia, ke hoʻomanawanui i ka mahina i ka pathological symptoms me ka nawaliwali, ia ka ho'ēmiʻana i loko o ke koko,, pōniuniu, tachycardia, syncope, somnolence, generalized tonic-clonic kāʻili 'ana, lilo o ka ike paka i, hyperthermia, irritability, gastrointestinal kahe ana ke koko symptoms (e like, ka luaʻi " kope kumu ") a me ka areflexia.

Ma keia hihia pono kaʻenaʻena symptomatic lapaʻau i ua kuhikuhi ma ka malama ana maʻamau ke koko, a me ka ÷ naehana hanu kuleana pili i.

I Kekahi Mau olelo ao no ka hoʻohana ana i ka lāʻau '

He aha oe e ike mua oe ke hoʻohana i ka lāʻau "Agapurin"? Reviews o kauka koi i ka lapaau mea maikai i keia hana, akā, e pono i ka iapaau ana e ia ma lalo o ke kanana 'mana o ke koko,. Ma keia hihia, i loko o nā mea maʻi me ka naau ka hoʻokō 'ole (maʻi) Ua koi' ia e loaʻa ai ka uku holo.

Ua E hoi e kaulana i loko o nā mea maʻi me kaʻike, o "mimikō" e lawe hypoglycemic ai ', i ka hana o keia Agena i nui nā māhele ke kumu no ke hai hypoglycemia. No ia mea, mahele lāʻau hoʻoponopono mea e pono ai lakou.

Me ka mea i ka wā hoʻokahi pono o ka lāʻau a me anticoagulants e akahele kanaka hoʻoponopono i ke ano o ke koko coagulation nenoaiu.

Ma nā mea maʻi i i iʻoki kino nei, e pono e mau kanaka hoʻoponopono i ka lehulehu o ka hemoglobin a me ka hematocrit.

pono e hoemiia ka lawelawe laʻau heluna i loko o nā mea maʻi me ka poe a haahaa ke koko.

Mua kanaka e pono ai i ka uuku mahele lāʻau.

E like me ka haʻawina, momoku me ka nui loa ho'ēmi i kā ka pākōlea hopenaʻoi loa o ka lāʻau.

pentoxifylline hoʻokaulike me nā infusion pāʻoihana e ke kulana kupono ma kela a me keia kanaka hihia.

AaOIeIOUIeXAOAaIN a me kekahi 'ano

Kaʻeleu waiwai pentoxifylline pinepine hoʻokāʻoi aʻe ana i ka hana o ka Luna e aloha ia ke koko clotting. Ia ai 'nā kauoha a me kaʻauhau'ēʻaʻe anticoagulants, valproicʻakika, thrombolytics, a me ka anitibiotiki (e laʻa me, ai' "Tsefamandol", "Cefoperazone", "tsefotetan").

Olelo mai la Agena maoli ka laulā o ke ku una hypoglycemic a me antihypertensive ai ', e like me insulina.

Mākou hiki ole ke olelo i ka lāʻau "cimetidine" me ka nui loa maoli ka lehulehu o ka pentoxifylline i loko o ke koko. Kēia maoli i ka pilikia o kaʻaoʻao loa.

Makeke-aaieieno? "Agapurin" lāʻau, hōʻike manaʻo o ka mea i hoikeia ma lalo, a me nā xanthines hiki aku ai i ka excessive ko mākou hopohopo pīhoihoi.

Nā Papahana no ka hoomakaukau pūnaewele, hōʻike manaʻo o ka mea, i ke kumu kūʻai

Uluwehi O "Agapurin" ua kūʻaiʻia i loko o aneane kela drugstore. Buy 60 papa (100 mg), oe e e hiki i ka awelika pono ma 250 Lūkini rubles.

Hoike o keia medicament Ua oi maikaʻi. Ia mea ke kumu ia pinepine 'ē aʻe ai' hoakaka ia i ka hoʻomanawanuiʻana, ka poe i pilikia i na moku ke koko.

It eʻike ai no hoi ia i ke 'ano nui kaulana lapaau "Agapurin" ma ka bodybuilding. Reviews bodybuilders aku nei au i keia mea paahana e e noonoo kaawale mai 'ē ai' i ka hoʻoikaika 'ana i ke koko pele. Ma hope o nā mea a pau, ka mea, o ka loa a me ka pono nae inexpensive.

ʻeleu medicament i mea e lawe 'âlapa, e like me ka mea ua hua mai la i ole wale i ke kino o ka injectable pāʻoihana, akā, no hoi ma ka papa palapala. Keʻena kūʻai lāʻau lapaʻau keia mea paahana hiki ke loaʻa ma lalo o nā inoa mea kani e like "Pentoxifylline" a me "Trental".

O ka papa kuhikuhi hana poe lāʻau hana māhuahua leo o na moku koko, hoemi koko (viscosity) a me ka ulu koko. A pau keia mea he alanui nui e hana Pumping ma haʻuki aʻo, ka wā ma laila mea i ka manao o ka ikaika e hana ana i nāʻiʻo pumping.

E hoʻohana i kēia ka lapaʻauʻia ua hoano e bodybuilders e e loa akahele, no ka mea, hiki wawe i ka overdose, a me ka helu o kaʻaoʻao loa.

E mālama "Agapurin" kaʻoi loa i loko o ka pouli, maloo wahi kahi he mea ole ke kōkua o ke kahi mau keiki liilii. Penei pūnaewele ana wela o ka lāʻau mea wale 10-15 degere. Pau lā hōʻike i ka'ōpala, a he mau makahiki. Ma hope iho o kēia wā, k hoʻohana 'ia kēia.

Ma ka hopena, ua hoailona oukou hookahi manawa hou i ole e e pakiko-hoonoho ana ia lakou iho e lawe keia laau lapaau. Duration o ka lapaau a me ka laʻau heluna E e nānā 'ia e ke kahuna lapaau e pono no i ua' Isaaka.