Calcitonin - He aha ka mea? Ka Ikepili no ka calcitonin. Calcitonin: maʻamau wahine

Thyroxine a me ka triiodothyronine - kēia mau thyroid hormones hua mai la ia e ka thyroid gland. Eia hou C-keena o ke kino e hiki ke pee calcitonin. He aha ka mea? Kēia hōmona mea he anakahi o ke kalipuna pūnao, a hiki e hua mai,ʻaʻole wale nō i loko o ka thyroid gland, akā, i loko o nā nā loko. Oi loaʻana i loko o ka maʻiʻaʻai a me ka thymus. Calcitonin ua komo i loko o ka rula o ka mea pōhaku pūnao, a mai ka luna 'Nine Inch' ole oia hoi o ke kaula o ka'amino nāʻakika. Kekahi 'aʻe' ana i kēia kaʻina hiki aku ai i ka mea o ka hōmona haalele i kona liluwelo haʻawina.

Calcitonin - He aha ka mea?

Inā e hiki mai ana, e loaʻa kekahi pilikia i loko o ke kino, kauka i noi e hooholo i ke kumu o ke koko hōʻike. I kekahi manawa, ua hōʻike mai i nā mea o ka nui nui o ka hehee ai e like me calcitonin. He aha ka mea? Kēia thyroid hōmona hua mai i loko o kona C-keena. He mea oncomarker e diagnose thyroid Ka maʻi 'aʻai , a makaikai i ka kalipuna pūnao i loko o ke kino.

He aha mea i ka hana o ka calcitonin?

O ka papa kuhikuhi hana o ka calcitonin mea i loko o ka manaʻo o ka antagonistic 'ana i ka mahalo i ka parathyroid hōmona, a ua hua mai ma ka parathyroid glands a regulates kalipuna pūnao a maoli he kona maʻiʻo i loko o ke koko. Calcitonin ka paipai 'ana i ka rula o ka kalipuna a me ka phosphorus pae. Receptors no keia waiwai i loaʻa i loko o ke koko (monocytes), keiki, akemāmā, akepaa, iwi keena ma ka Central ko mākou hopohopo'ōnaehana, reproductive nā loko, me nā puʻupaʻa.

Ka iwi o keia hōmona ua ālai 'ka leaching o ke kalipuna, no laila ua loaʻa ka kākoʻo no ka' ole o nā iwi. Calcitonin mea nui loa i loko o hihia ma na nā minelala hao i hoopauia ma ka nui mea. Oia ke kulana home 'ole ia lŘlŘ oiai kaʻeleu ulu ana o ke keiki, hāpai keiki, a lactation.

Ke koko, keia hōmona mea i nui, a mai ka hypocalcemic hopena. Calcitonin ka paipai 'ana i ke kala o ka paʻakai i loko o ka mimi a me ka emi lākou ka hopu i loko o ka naʻau liʻiliʻi. Ua hoi emi koko pae o ka phosphorus, a loaʻa ka hopena ma luna o ka digestive'āpana a me nā puʻupaʻaʻelua.

Ke thyroid gland produces ka hōmona i loko o ka poe liilii, na mea, a me kona maʻiʻo i loko o ke koko ka loa nui. Ua hiki ke hua mai i loko o ka gut, akā, i loko o ka loa miniscule nā māhele.

Calcitonin i loko o ke koko

No ke aha la ka mea pono, e lawe mai Ka Ikepili ma calcitonin? O C-keena, e paka i kēia hōmona, i ka maʻi 'aʻai ulu thyroid - medullary carcinoma, a C-aeea carcinoma. I ka ulu ana o ka hikoko Ua lohi, akā, nui paʻakikī, hohola metastases e lymph aka wahi i loko o ka'ā'ī, a me na mea he nui 'ē aʻe nā loko. He loa paʻakikī i ka chemotherapy.

Mai C-aeee paka i ka hōmona calcitonin, konaʻoi ala i loko o ke koko ke hōʻike i ke alo o medullary thyroid Ka maʻi 'aʻai. Kakahiakaʻike, o keia maʻi i hoola i ka nui helu o ke kanaka ola.

Ma ka hihia e ke koko o ke calcitonin?

ʻeho keena Ua pinepine hereditary. A pau nāʻohana o ka hoʻomanawanui pono mau E lūlū mai ke koko i kēia hōmona. Ma waho o ka lapaʻau 'ana i hoʻohana e kuhikuhi i ka recurrence o ka malignantʻeho. Inā i ka histology hana hoopaa i ke alo o medullary Ka maʻi 'aʻai, a laila, ma hope koko calcitonin, e pono e lawe i kela 3 mahina a me na malama keu eono.

Aia i nā kumu no ka hele i kēia ninaninau:

• e kuhikuhi i na mai i kupu mai ma muli o ka'āno'ē kalipuna pūnao;
• no ka meaʻike, o ka osteoporosis;
• e hooholo ka hana hikoko;
• me ka pinepine fractures a me ka hoailona o ko lākou maʻi.

Norma calcitonin

Ua hoʻomanaʻoʻia ai ia i ka mea, i keia mau mea me ka haahaa e paa ana o ka hōmona mau hae ma ke koko hoao i ka calcitonin. Norma e ia i loko o ka hanana i ia mea 'Aʻohe pae i loko o ke koko. He mea nui i ka mea aole e oi aku i ka luna palena o ka maʻamau.

Ma kekahi mau keʻena hoʻokolohua uku o calcitonin i loko o ke koko e ĸokoĸa ana nä pane. Keia ua wehewehe ia e ka mea iʻano reagents a me ka hana kūikawā lako a hoʻohana no ka mahele. Eia hou, i ka hopena hilinaʻi nui ma luna o ka makahiki a me ka wahine. A like ma nā kiʻina hana: ma'ūhū immunoassay a me ka immunohemilyuminestsentnym.

Immunoassay iaoia i na kēia maopopo kahi loina ia hōmona e like calcitonin:

• ana i loko o na wahine - 0,07-12,97 pg / ml;
• uku o na kanaka - 0,68-32,26 pg / ml;
• kūmau i loko o na keiki - mai i 79 pg / ml.

Kūmau ma immunohemilyuminestsentnom hana:

• Women - 1,46 pmol / L;
• kāne - 2,46 pmol / ho'āo ai.

I ka hopena o ke Ka Ikepili i ĸokoĸa ana nä pane ma ka wahine i hāpai keiki, a iā breastfeeding.

Pehea hiki ke olelo aku nei au i ke kiʻekiʻe kiʻekiʻe o ka hōmona?

Inā ka hoʻomanawanui ua calcitonin mahuahua, a me ka ole pehea, ma kekahi hihia e ia mea he mea nui pilikia e pono nui ma-hohonu ka ninaninau ana o ka lahui a me ka 'oihana kupono poe akamai i mea. Inā ka 'inideka o calcitonin i loko o ke koko o ka oi ma mua o 100 pg / ml, me ka aneane 100% oiaio, ke olelo o ka malignancy. Ua oi ae ke kiekie hōmona pae ua, ka nui ka manawalea o kaʻeho, a me ka nui o ka pahiki o kaʻimiʻana i loko o ka lymph aka wahi, a me nā loko kona metastases.

Inā he hoomanawanui i thyroid nodules, a ua waeiaʻe oia i like kui kele ma biopsy, a hoike mai i ka mea e benign, a me ke koko calcitonin hōmona nui ae, ia mea pono, e manaoio aku i ka hopena o ke Ka Ikepili, no ka mea, ua kokoke mau oiaio. I ka wā o ka loa ikaika mahuahua i loko o ke koko hōmona pono hanaʻoki kino i ka mea e loa wehe i ka thyroid gland pu me ka puni lymph aka wahi.

Eia kekahi medullary Ka maʻi 'aʻai hōmona pae e ala hou mai ai ka wā i kēia mau maʻi:

• C-aeea hyperplasia;
• ; Ellison - Zollinger
• kanakaʻona mau cirrhosis;
• Ka maʻi 'aʻai o neuroendocrine ano;
• pernicious anemia;
• psevdogipoparatireoidizm;
• carcinoid maʻi pale;
• thyroiditis a me ka pancreatitis;
• akemāmā maʻi o benign ano;
• maʻiʻaʻa puʻuwai ole.

Ma ka hōʻoiaʻiʻo aku o kēia mau maʻi e eʻoiaʻiʻo, e pono ia lakou.

ka hopena

He nui nā mea maʻi, kauka i koi 'ia ke koko ho'āʻo haawi i ka calcitonin. He aha ka mea? Kēia thyroid hōmona, i mahuahua ai lakou i pae ke hōʻike i ke alo o ka malignantʻeho o ke kino. Me ka 'eleu ka loaʻaʻana o ka medullary Ka maʻi' aʻai, aʻoki lāʻau lapaʻau hana hiki aku ke olelo i keia pilikia mea ole hou. Eia hou, i ka maʻi ke kumu hōmona pae mahuahua ana a me nā kumu i me ka 'eleu lapaau i ke kauka hiki e hana ana.