Embryonal rhabdomyosarcoma: lapaʻau, prognosis

Rhabdomyosarcoma pili ia i ke ano o ka sarcoma - palupalu'aʻaʻa Ka maʻi 'aʻai, iwi a connective'aʻaʻa. Kaʻeho Ua loa paha, e ana i loko o nā nāʻiʻo i pili i ka iwi. Rhabdomyosarcoma - malignancy ka hoʻomakaʻana i loko o ka skeletal Muscle. Ka mea, hoʻomaka i loko o kekahi i kekahi hapa o ke kino paha ma kekahi mau wahi.

Microscopically rhabdomyosarcoma i loko o nā mākua i ka palapala o elongated a ua hoʻokōʻia keena bizarre. More ano o keiaʻeho o ka noho 'ana kamaliʻi.

'ano o ka rhabdomyosarcoma

Rhabdomyosarcoma o ka mea maloko 'ole e mahele ia i hoailona ia mea:

1. Embryonal rhabdomyosarcoma keena he o ka puni a me ka fusiform kona hoʻokolokolo 'cytoplasm hōʻike he lonikū a transverse striations. Kēiaʻano o ka rhabdomyosarcoma ana aku pinepine. Eia kahi mea akaka embryonal rhabdomyosarcoma i loko o nā keiki a me ka adolescence. Ua Ua Aia i loko o ka ai a me ke poo, ma ka wahine, i loko o ka nasopharynx. Ke pā lonoaʻili o ka hikoko, e pāhawewe Inc, akā, ua prone i kokololio relapse.

2. Alveolar rhabdomyosarcoma ua haku o ka pae ana o keena a puni a me ka'ololaha, a ua hoopuniia oukou e septa o connective'aʻaʻa. No kēiaʻano o ka hikoko wehewehe aku ma keʻano ma ka wāwae a me na mea kaua, abdomen, umauma, loira a wahine nā loko. Pinepine ka mea, hiki ke loaʻa i loko o adolescents a me nā mākua ma ka lala. Prognosis mea ilihune.

3. haku mele 'ana pleomorphic rhabdomyosarcoma - polymorphic kālī-hoʻokino, lipine-me, hoku-hoʻokino keena o kaʻeho a i ikeia ma na wawae a me na lima o na kanaka. E like me ka rula, rhabdomyosarcoma ulu ia lŘlŘ koke, a 'aʻole i ka eha a me ka ooieoeiiaeuiuo kāna hana. Ua lŘlŘ wale aa koko. Ka mea, pinepine ulu ma kaʻili, a uhi i na mai hehe, ho okumu i exophytic, kahe ana ke kokoʻeho.

kamepiula kumumea

Mawaena o ka? Aneie aʻe i loaʻa ia, e hoomahuahua i ka pahiki o ka hanana o kēiaʻeho. Keia i kekahi, mai ka hapanui o ka rhabdomyosarcoma Ka maʻi 'aʻai.

Aie i ka mea i ua ole ike kumu o kaʻeho? Acaeoey pono, ua hiki ole haawi aku i kekahi aʻo no ka ho'āʻo ana kona ho okumu. Eia naʻe, ua pono hoike aku i ka manao ana me ka nui kūpono lapaʻau o nā mea maʻi me ka rhabdomyosarcoma hiki i kekahi manawa e loa ola.

'Ākena Makaʻu no keʻano o ka embryonic rhabdomyosarcoma ka poe hana pela genetically ka manao o lakou maʻi:

1. Li-Fraumeni maʻi pale mea pohihihi keia maʻi i loko o i ili mai iā ia kāna moʻolelo,'ōewe pōʻino ka wā nalowale kekahi makua i ke alapine (frequency) kiʻekiʻe holoholona anoʻehoʻAno ae la. Ili ma keia pathology ho'īli specificity o kaʻeho'aʻaʻa reactions ka wā dramatically maoli ka pahiki o ka ulu hikoko ma kekahi kakahiaka nui kona mau makahiki (30 makahiki).

2. Neurofibromatosis mua type - ka loa e like me ka ili maʻi i kumu i ka helehelena o ka predisposition e malignancy.

3. maʻi pale Beckwith-Wiedemann - pathology, a ua wehewehe aku ma ka macrosomia, macroglossia a me omphalocele. Ua mea i maopopo mā i loko o na keiki o ka mua paia o ka abdomen, hernia, neonatal hypoglycaemia, ka divergence o ka rectus nāʻiʻo.

4. Costello maʻi pale - he ke nānā maʻi, a ua wehewehe aku ma congenital malformations: ulu retardation, lohi lehalehu t hiʻona, ili hou.

5. Noonan ka maʻi pale - he aaiaoe kāna hana wehewehe aku ma ka pōkole kona kino no i na deviations, a ma ka somatic ulu ana. Ua hiki ana i loko o ka 'ohana a ma kekahi o kona mau lala.

Keiki ka mea i hānau kaumaha a me ka ulu, i oi aku mamua o na mea e ae, o ka pilikia o embryonal rhabdomyosarcoma. E like me ka rula, nae, na kumu o embryonal rhabdomyosarcoma mea IKE OLE IA. A hoailona o ka maʻi o ka helehelena o kaʻeho lilo nui a me ka oi.

symptoms

Symptomatology o ka maʻi o ka maʻi 'aʻai ua nānā'. Koi koke nīnau aku i ke kauka ina keiki i helu 'ia ma na hoailona o ka maʻi' aʻai.

• edema a nani, e māhuahua ana ma ka nui paha i maalo ae la oia, i kekahi manawa ola;
• bulging mau maka;
• loa headache;
• pilikia me ka defecation a me ka urination;
• ke koko ma ka mimi;
• kahe ana ke koko i loko o ka rectum, ihu a me ka puʻu.

lapaʻau '

I ka lā, epekema ka 'ike rhabdomyosarcoma a kona mua overt symptoms.

Ka mua na hoailona o ka maʻi 'aʻai - kūloko nani a induration,' aʻole i i pilikia ma mua a me ka eha. Kēia symptom He ano o ka rhabdomyosarcoma, i na mea kaua, a me nā wāwae torso.

Inā kaʻeho ua IIeEeAIEUIeXAIIUE i loko o ka abdomen a pelvic wahi paha i abdominal eha, ka luaʻi paha constipation. Ua embryonal rhabdomyosarcoma o ka retroperitoneal hakahaka. More kākaʻikahi, ulu i loko o ka biliary'āpana, rhabdomyosarcoma kumu jaundice.

Inā he mea i hoʻohuoiʻia no kēiaʻeho, ia mea e pono e hooponopono i ka biopsy, a e hoakaka i ke ano o ka rhabdomyosarcoma originated.

Ma ka hapanui o hoopii, rhabdomyosarcoma aicieeaao i mau mea kahi ia ua hikiwawe akomi i, no ka mea hoike, i ka nasal lua 'ole ma waho o ka'ōnohi a poʻopoʻo. Inā na maka bulging, a nasal secretions hou, oe e ike koke kukakuka i ke kauka me ka mahuʻi muaʻeho no e diagnosed ma ka kakahiaka kahua o kona ulu ana. Ma ka hihia kahi rhabdomyosarcoma akaka ma luna o ka ili o ke kino, ka mea, ua hoopuni ia akulla 'ole i ka hoʻokolokolo pono' ana. Kēia no laila,-kapa embryonal rhabdomyosarcoma pahee'aʻaʻa.

I ka 30% o nā mea maʻi me ka embryonal rhabdomyosarcoma mea ma kekahi kakahiaka nui ke kahua me ka mea hiki ke loa wehe ia. Akā, me ka uie kekahi hapanui hewahewa o nā mea maʻi piha hoike hōʻike metastases uuku, hana maikaʻiʻole o ka mea pono i ka alo o ka chemotherapy.

Embryonal rhabdomyosarcoma, a i aia i loko o ka hoʻi, kahi pinepine hua mai la i na keiki liilii, a ua loaʻa nā mākua i nā keiki i ka wā e kaka ana. Inā hikoko ana i loko o ka urinary'āpana, ka mea, i ole ma ka urination ole koko hookuuia - symptoms i hiki ole ke AOON.

ʻeho ke kahua

1. Ka mua anu u. Kaʻeho paha e kekahi nui, akā, ka mea, i ole i palahalaha ae i ka lymph aka wahi o ka'ōnaehana, a ua noho i loko o kekahi o ka prognostically ano mau o ke kino.

- mau maka a periocular wahi;

- poo a me ka'ā'ī (Ma waho aʻeo ka'aʻaʻa i loko o ka lolo a me ka spinalʻaha wahi);

- ka bile ducts a me ka laau awaawa, bladder;

- ma ka uterus a hoʻi.

Wahi ma waho o ka helu, e manaoia noho lakou malaila pāhili.

2. O ka lua o ke kahua. Haanou ana o kekahi o ka noho lakou malaila cii (cii a e nalowale ana ma o ka 'ano). ʻeho nui ka emi o 5 knm, a ua i palahalaha ae ai i ka lymph aka wahi i hana.

3. ke kolu o ka anu u. Kaʻeho o Nyos i loko o kaʻenemi wahi, a hālāwai me kekahi o na ana ma lalo nei:

- i ka nui o kaʻeho emi o 5 knm, a me ka mea i palahalaha ae ma ka aʻe lymph aka wahi;

- kaʻeho mea nui ma mua o 5 knm, a me he mea he pilikia i mea e palahalaha ae i ka hapa lymph wahi.

4. E ka ha o ke kahua. ʻeho nui hiki e kekahi, a me ka mea i hohola i ka lymph aka wahi e hiki mai ana. Aia i Ua i ka laha o ka maʻi 'aʻai, e mamao mau mea o ke kino.

kamepiula pūʻulu

Ia hoʻomanawanui kamepiula pūʻulu e hoʻoholo i ka likelihood o recurrence o rhabdomyosarcoma. pono ke hookipa aku i kekahi keiki e launa mai i ka hana maikaʻiʻole mai embryonal rhabdomyosarcoma, hou chemotherapy e lilo emi likelihood o kaʻeho recurrence. View anticancer lāʻau, laʻau heluna a me ka helu o nā kau - i keia me ka nānā 'ana i ka pilikia a hiki i kekahi keiki haawiia - haʻahaʻa, waena paha kiʻekiʻe.

lapaʻau koho

Nā mea maʻi me ka embryonal rhabdomyosarcoma hiki ke hana ia ma kekahi aoao.
Lapaʻau komo ai malignant hikoko hoʻokaʻawale methodologies a ua manaoia e e kuʻuna. Other i kūpono nō ma lalo o lapaʻau e hookolokolo ai. Lapaʻau e hookolokolo ai i akoakoaia e hoʻoikaika nei ano o ka hana maikaʻi a hoʻoulu i ka nui o kaʻikepili o ka Hou Loa ki ina hana like o ka hana maikaʻi i nā mea maʻi me ka rhabdomyosarcoma. Inā like me ka hopena o ka lapaʻau hoao ana, eia kahi mea akaka i nā kiʻina hana hou o ka lapaʻau mea i oi ke ku una, me ka hou lapaau hele i loko o ka mahele o ka kuʻuna.

No malignant hikoko kamaʻilioʻana, e hōʻike i loko o kekahi mau mea o ke kino, Ua pili ka nui helu o nā kūlana kanaka. Lapaʻau o rhabdomyosarcoma i keiki kākoʻo ma pediatric oncologist.

I waena o nā kiʻina hana o ka lapaʻau, ma laila nō kekahi e hiki iʻaoʻao waiwai, a hiki i ka wa a ka iapaau ana i hele mai i ka lōʻihi manawa.

ʻoki kino

ʻoki lāʻau lapaʻau hana, a ana o kaʻeho, ua hoʻomano hoʻohana 'ia ma ka iapaau ana o ka rhabdomyosarcoma. Keia hana ua kapaʻia he "akea kuʻikahi excision". Kēia 'ākeʻakeʻa mea e wehe' ana o kaʻeho, a puni'aʻaʻa pu me ka lymph aka wahi mea no hoi e loli ai rhabdomyosarcoma. Lapaʻau kekahi manawa mea e hana kekahi mau hana. I ka olelo hooholo ma ka hookohu ana o ka hana a me kona 'ano hilinaʻi nui ma luna o ka kēia kumumea:

- kau i ka palapala wahi o kaʻeho;

- i kekahi keiki hana o ke kino loli ana ma kaʻeho;

-ʻeho muli o radiotherapy paha chemotherapy, i hiki ke hoʻohana 'ia ma ka makakoho manawa.

Ka hapa nui o na keiki i ka wehe 'ia o ka holoʻokoʻa ka leo o kaʻeho ma kaʻoki kino mea,ʻaʻole hiki.

Embryonal rhabdomyosarcoma pahee'aʻaʻa mālama i ia e hana ma kekahi mau wahi o ke kino, kela mea keia mea o ka i pono kona mau hana. ʻoki lāʻau lapaʻau 'uao ua hōʻike ma ka hihia o ka rhabdomyosarcoma wahine a maka, ina ka biopsy hoʻopaʻa i kaʻike,. Ma mua o ka hana hiki e häʻawi mai ai iä chemotherapy paha radiotherapy e ho'ēmi i nui hikoko, i hiki ole ke hoʻohana ma, e Nohie i ka hana o ka wehe i ka maʻi 'aʻai.

Pela hoi, aole ina ke kauka hiki ole wehe i kaʻeho holoʻokoʻa, E e malalo iho hoʻomanawanui iki mai i ka pau ana o ka hana i ka chemotherapy e uhi Ka maʻi 'aʻai aeee e ola. A me ka chemotherapy, pāhawewe Inc ua hoʻohana 'ia. Iapaau ana nona ma hoemi i ka pilikia o ka recurrence o ka maʻi ua kapaia adjuvant Inc.

pāhawewe Inc

Me kēiaʻano o ka lapaʻau hoʻohana X-Ray 'ole' ē aʻe pāhawewe. Ka pāhawewe ke Inc kuhikuhi i kekahi mea, e pepehiʻeho keena paha, e hooki aku i kona ulu. Kona palapala noi i ka lapaau ua loaʻa mau aoao e radiotherapy - mawaho a me na.

Mawaho hoʻohana he pāhawewe kahi mawaho o ke kanaka kino no irradiating kaʻeho. Kūloko pāhawewe Inc a brachytherapy irradiatesʻeho me ka hoʻokomo 'ana o radioactive' ona i loko o ka wahi koke o ka loko o ke kanaka kino. Ua Ua hoʻohana 'ia no ka hana bladder Ka maʻi' aʻai, ke poo a me ka'ā'ī, prostate, vulva.

ʻAno o ka pāhawewe Inc a me ka mahele lāʻau hoʻoholo ma ka makahiki o ke keiki i ka a me ke 'ano o kaʻeho, o ka puka mua IIeEeAIEUAA akā, i ke alo o ke koenaʻeho, a me ka degere o kaʻeho kākau inoa' ia hapa lymph aka wahi ma hope oʻoki kino.

chemotherapy

Kēiaʻano o ka maʻi 'aʻai lapaʻau e hoʻohana lapaʻauʻia, e hooki aku i ka ulu ana o Ka maʻi' aʻai keena. Chemotherapy ai 'kōkua pepehi i kēia mau keena paha, e pale aku i ko lakou moku. A systemic chemotherapy ai 'i lawe hōʻike waha ai injected intravenously paha intramuscularly. Hiki i loko o ke koko, ai 'aha ka maʻi' aʻai keena ma ke kino. I ka wā o nā 'āina chemotherapy ai' i injected 'ana i loko o nā loko a me ke kino cavities, e like me ia ma ka cerebrospinal loli. Me ka hui pu chemotherapy ua pinepine hoʻohana ', i mea i ka iapaau ana i ua hoʻohana' oi ma mua o kekahi Anati-Ka maʻi 'aʻai lāʻau. chemotherapy iaoiaeii Ua wae ke kaumaha ma muli o ka 'ano a me ke kahua o ka? acaeoey o ka neoplasm.

Chemotherapy ua hoike mai ai i na keiki i ka i malamaia lakou nei, no ka rhabdomyosarcoma. Ua apono 'oe e kń i ka likelihood o ka maʻi recurrence. Ke koho ana o ka lapaʻauʻia, i ka mahele lāʻau, a me ka helu o nā kaʻina hana i ho'ākāka 'kamepiula pae rhabdomyosarcoma.

New ohe.

New ano o ka lapaʻau rhabdomyosarcoma, maalo ae la oia i ka hoʻokolohua.

• Nui nā māhele o ka chemotherapy i loko o ka huipūʻana me ka hooko ana mai anei i aeea transplant. Ka papa hana i ka mea hiki ke hoonohonoho i ka hope o ka hematopoietic aeee i e luku i Ka maʻi 'aʻai lapaau. ʻiliahi koko aeee i wehe 'ia ma mua o ka hana maikaʻiʻole o ka iwi ka lolo a me ke koko o ke ahonui a me ka mea i ka malamaia. Ma ka pau ana o ka chemotherapy raskonserviruyut conserved anei i keena, a hoi aku la i ka hoʻomanawanui ma infusion. Pela na keena koko e regenerate.
• Immunotherapy. A lohe o keia ano o ka hana, e kaua aku maʻi 'aʻai ka hoʻohana' ana i ka'ōnaehana paleʻea'ōnaehana o ka hoʻomanawanui. Lawelawe ai 'mea e hoʻoikaika' a hoihoi aku i ka pale aku ia lakou maoli i ka maʻi 'aʻai. Keia hana ua kapa biotherapy o hikoko.
• Hoʻomāka Inc. Kēiaʻano o ka Inc ua kuhikuhi ku metastasis. Hoʻomāka Inc ua muli ma ka hoʻohana 'ana i ho'ākāka' ia i nā mea'aʻaʻa e nakinaki i ka maʻi 'aʻai keena. Mau nā mea'aʻaʻa i like iʻike mau nā mea'aʻaʻa o kanaka kino. Pela no ka mea, ho i ke kiʻekiʻe-ʻenehana lāʻau. Mahalo i hoʻomāka Inc ma ka iapaau ana o "kemika" hiki ke ike i ka hoouka wale nō Ka maʻi 'aʻai keena me ka hoʻopōʻino ola keena. I ka rhabdomyosarcoma ma angiogenesis nā mea kūpale e hoʻohana i ka pale kaua Inc. Mau ai 'ole i ke kahua o ka moku i ke koko i loko o hikoko. Ua hiki aku i ka mea i kaʻeho starves a me i pau ka moni e ulu ana. Angiogenesis nā mea kūpale a monoclonal nā mea'aʻaʻa -ʻano o ka Luna undergoing lapaʻau hookolokolo no ke kaōhiʻana embryonic rhabdomyosarcoma.