He aha "Lyrics" papa? Ka hoʻohana o ke kumukuai

Medicine "Lyrics" (papa), i ke kumukuai o ka i mea mai ka 700 a hiki i 4000 rubles, -. Hoʻomano-ike lāʻau. ʻeleu waiwai - pregabalin - Analog o gamma-aminobutyric (me Gaba)ʻakika (me Gaba). Hope i loko o ka pauku, e haawiia mai e annotation i ka lapaʻauʻia. E loaʻa iā mākou mai ka huaale "Lyrics" hoʻohana 'ana i nā mea maʻi.

ʻano papa hana o ka hana

Pregabalin hōʻike mai kona hopenaʻoi loa i loko o ka iapaau ana o diabetic neuropathy a me postherpetic neuralgia, no ka a huaale "Lyrics" hoakaka ana i ka 13 pule me ka kela laʻai ana i kela 2 manawa, a i ka 8 pule, 3 manawa i ka lā. E kū'ē i ke kāʻei kua o ka ulu ana o ka mea i hōʻike mai i ka iaʻaoʻao waiwai. Pili me ka fibromyalgia mea maopopo i nanaia ka ho'ēmiʻana i loko o ka eha symptoms kuhikuhi ana e lawe ana i ka lāʻau 'nā māhele o 300-600 mg no ka lā. Kela la i keia laʻau heluna o 450 mg a me 600 mg hiki ke hoohalikeia no ka hoʻokōʻana, akā, i ka hope o ua emi pono tolerated. Ke k ho'ēmi i kā ke oolea o epileptic kāʻili 'ana, a papa "Lyrics" waiho aku i ka papa o ka 12 pule, 2 a 3 manawa no ka lā. I? Eaia ia lŘlŘ ka hookahi kumu o kaʻaoʻao 'ole a me ka laulā o ka lāʻau ma keia mahele lāʻau. kāʻili 'ana i alapine (frequency) hoʻomaka e emi ia i loko o ka mua pule o ka nohoʻana. Symptomatology o generalized ka iini kāna hana hōʻike i ka welelau o, e emi ma ka mua i nā lāʻehiku o ka lapaau. Mahope oʻewalu pule 52% o ka lāʻau e hoomanawanui i ka loaa ana pregabalin a me ka 38% o nā mea maʻi e loaa ana placebo, hōʻike he 50 pakeneka ka ho'ēmiʻana i loko o symptoms o ka Hamilton me ka unahiʻole (Hama-A).

Pharmacokinetics

Ka medicament "Lyrics" (papa) - User keʻae i keia - i loko o ka paipai i kela la nā māhele me kaʻaoʻao pharmacokinetic wehewehe aku linearity, haʻahaʻa (<20%) interindividual variability. Hou noi o na pharmacokinetics o ka lāʻau hiki ke wānana ma ke kumu o ka pa alima o ka laʻau heluna aeaiiuo. No laila, mau kanaka hoʻoponopono i ka lehulehu o ka hana 'Oponopono mea i pono. Pharmacokinetic kiko'î o ka lāʻau "Lyrics" i loko o nāʻaʻa ola, nā mea maʻi me ka epilepsy ka poe i lawe antiepileptic Inc, e like me ka loaa ana i ka lāʻau no ka uhiʻeha syndromes i like.

Omo a me ka hoʻopau

Ma hope o ka lawe ana ma luna o ka nele'ōpū pregabalin ua kemu loa koke. Hoʻokahi hola ma hope, i ka wai koko Cmax loaʻa like ia ana no ka manawa mua, a me ka hai. Ma ke kāʻei kua o pregabalin ku una bioavailability mea ma ≥90% a mea kuokoa o ka mahele lāʻau. Ua loaʻa Equilibrium wā lawe hai hou i loko o ke au o 24-48 hola. Inā ka lāʻau ua noi ma hope o kaʻai, e hoemiia ka Cmax ma 25-30%, a māhuahua kona e piʻi like manawa i 2,5 hola. Naʻe, i ole i ole clinically nui ia ma luna o ke omo o ka lāʻauʻai. Holo nōhie ka lāʻau excreted ma nā puʻupaʻa ua hoʻololiʻia. T1 / 2 awelika o 6,3 hola.

Pharmacokinetics ma kūikawā hihia

Inā 'oe compromisedʻaʻa puʻuwai papa, ia mea e pono ke lawe i ka mooolelo o ka peculiarity o pregabalinʻae, ia mea pololei hapaʻauhau i ka creatinineʻae. Holo nōhie ka lāʻau excreted ma nā puʻupaʻa, nolaila, ia mea e pono ai ma ka hihia o ka 'aʻe' ana o ko lakou mau oihana, e emi i ka mahele lāʻau. Kaawale mai na puʻupaʻa, ke medicament hiki ke wehe 'ia ka pono, mai ka wai koko ma ka hemodialysis (4-hora hemodialysis kau e haawi mai ai 50% emi ma ka lāʻau lehulehu ma ka wai koko), a laila, oi pono koho lāʻau mahele lāʻau. A kūikawā like o na pharmacokinetics o ka Luna "Lyrics" i loko o nā mea maʻi me kaʻole ake hana i ole, ua hana.

Pregabalin metabolized kokoke i hooleiiaʻi mawaho, ua hōʻike pū me ka mimi i loko o ua hoʻololiʻia palapala, nae hihia hoʻi ake papa 'aʻole ole me ka nui loa pili i ka lehulehu o ka lāʻau i ka wai koko. Ka wā e hāʻawiʻia i nā mea maʻi i ka lāʻau ma luna o 65 makahiki o ka makahiki, e pono e hoike aku i ka manao ana me ka makahiki Pregabalinʻae mālama i ke emi. Inā he kūpuna kanaka o ua hoʻemiʻaʻa puʻuwai papa, ia mea e pono ai ka ho'ēmiʻana i loko o ka lapaʻauʻia hoakaka ia mahele lāʻau.

laʻau heluna

Na kela la nui o ka la hoomalolo ho'ākāka 'ia i loko o ka 150-600 mg no ka lā. Komo ua lawe mai i na manawa elua a ekolu manawa, nānā 'ole o ka palaoa. Ka medicament "Lyrics" (papa) manual ia kekahi e lawe me ka neuropathicʻeha ma 150 mg no ka lā. Inā paha e mahuahua i 300 mg ka loaʻa kanawai a me ka tolerability maikaʻi kekahi hebedoma kela la i keia mahele lāʻau (i hoʻokohu 'ia "Lyrics 300" papa). Inā pono, i ka i kā mākou mahele lāʻau o ka 600 mg no ka lā e e lawelawe hoʻokahi pule ma hope. Like me pōpilikia mahele lāʻau ma ka iapaau ana o ka epilepsy. E like me ka mea i haiia ae maluna,, e waiho lāʻau no ka iapaau ana o ka fibromyalgia, i na papa "Lyrics" ua lawelawe i loko o ka mahele lāʻau o ka 75 mg no ka lā i loko o nā nā māhele. Ma hoʻoulu i ka mahele lāʻau a hiki i 300 mg lakou aloha ia i ka loaʻa kanawai a me ka tolerability. Inā he mea i maikaʻi hookoia, mahuahua ka mahele lāʻau a hiki i 450 mg, a ina i nele i - kekahi pule i 600 mg. Hana generalized uunu nui kāna hana hoʻomaka me ka mahele lāʻau o ka 150 mg. I ka hebedoma, malama ana i na loaʻa kanawai a me ka tolerability, me ka kela la i keia mahele lāʻau mahuahua i 450 mg, a ma hope o 7 lā - mai i 600 mg (inā pono).

ana mai o ka lāʻau

Inā pono, lapaʻau discontinuation ua waiho i ka hana ia ma ka liʻiliʻi loa no ka pule i gradual ka ho'ēmiʻana i ka mahele lāʻau. E hoomanawanui i ka poe i hihia hoʻi hakuʻala hana, lawe mai kanaka koho o nā māhele. Ma ka hanana o adverse loa i loko o nā mea maʻi loaaʻano "Lyrics" Akala a-hoʻokoe Nāna e koho i ke akamai. Mawaena o ka loa e like me ka mea i 'ano like me ia e ke i hoike ia ai' "Mydocalm" "Apizartron" "Sedavit" "Ambene".

hoike

Ka lapaʻauʻia ua pono no ka hoʻopau o neuropathicʻeha, me adjunctive Inc no ka helehelena hopu o ka epilepsy, i mea hele pu pahaʻaʻole pu ma haumāna generalization. Loa i hōʻike mai no ka iini kāna hana generalized ano, e like me fibromyalgia.

Contraindications

'Aʻohe' ikepili ma ka hoʻohana 'ana i ka lāʻau i loko o nā keiki a me nā adolescents i ka 17 makahiki kauoha aupuni. Ma pili ana me keia ka lapaʻauʻia ua hāʻawi wale i nā mākua. Contraindications nā hereditary maʻi like galactose intolerance, lactase deficiency, e like me malabsorption o ka monakō koko / galactose. Ke koʻi lipi ma uaʻAʻole i hōʻike no ka hypersensitivity. E malama i ka akahele ana o ka lāʻau i loko o nā mea maʻi me kaʻaʻa puʻuwai a me ka naʻau a 'ole.

ʻaoʻao waiwai

E like me ka hana o ka lapaʻau noi o ka medicament, ma na hiohiona drowsiness a me ka pōniuniu like undesirable hopena. Mauʻike manaʻo kamaʻilioʻana, e ana i ka lōpū a mehana loa. I waena o nāʻaoʻao ona kūpono ma ka discontinuation o ka lāʻau lapaʻau, ka mea e e kaulana asthenia, ka hilahila, blurred hihiʻo, incoordination, ataxia,ʻike ākea edema. Nō hoʻi i waena o ka hopena maikaʻi 'ole kaulana headache, lilo o ka ike paka i, ke kāʻili' ana, haanou ana o ke alelo, diarrhea, nausea, keratitis. Kākaʻikahi ka i itchy ili a me angioneurotic naoh. Aia i urinary ka mālama, pulmonary edema a me ka gynecomastia. I waena o nāʻaoʻao 'ole ua kapaia luhi.