He aha nā platelets? He aha kā lākou kūlana ma ke kino? A maʻi platelets mahuahua

Platelets ua uuku na ole-nukelea hana oihana mua o ke koko. Ka mea, o ka pae'āina ma ka hemostasis (ka luna 'o reactions pahuna ma noho kahe ana ke koko a me ka aʻoaʻo). Platelets e kokoke mai a me ka'ololaha ma shape. Ke anawaena o ka halepaahao mea ma waena o elua a me eha microns.

Ma na moku ke koko, e hoʻonohonoho platelets ma na paia a ma ke koko. I ka lua o ka hihia, na keena i loko o ka mana noho iluna moku'āina, a mai ka pā hōkū shape. platelet ho'ā hope ka poʻea pau i huli hou ae la ko lakou mau ano apau loa: na keena e sphericity a me kekahi 'ano protuberances (pseudopodia). Ma keʻano o kēia mau keʻano o ka hanaʻana i hiki hoi ke koko hehee wale loʻohia i kekahi i kekahi a hiki i ka pa o ka moku me ka pōʻino. O kŰia ua kapaia aggregation (sticking pu). Platelets, eia hoi, e komo waiwai i ka mea pīlali (kū pūʻuoʻuo), degranulation (hoʻokuʻu o Contents), clot retraction (a piha kaawale ana o ka hoemi koko clot mai ka lāʻau lapaʻau). Ma kona ili honua, e hiki iā tolerate fibrinogen, he waiwai biologicallyʻeleu (serotonin), anticoagulants, a me ka'ōnaehana paleʻea eiiieaenu (ai hoʻolahaʻia) na keena.

By mea pīlali a me ka platelet aggregation hoʻolako hemostasis ma ka liʻiliʻi-caliber moku (aeee loaa ma ke kahua o ka pōʻino). Like stimulants coalescence kaʻina i adrenaline, thrombin, collagen, serotonin. Me ke komo 'ana o thrombin o ke kahua keʻano o ka hanaʻana (pseudopodia). Platelet pellets pihaʻi me clotting kumumea (serotonin, peroxidase'ūhū platelet fibrinogen, adenosine diphosphate (ADP), serotonin, platelet-loko ulu ololi, av Willebrand ololi).

Iloko o ka retraction o ke koko clot ia lŘlŘ mea pīlali e fibrin filaments, a hookuu trombostenina i kikiʻo ma luna o lākou. I ka hopena o ka hōʻailona, a me ka kihi loa i ka lopi, pela ho okumu i kekahi, iniiaiie thrombus.

Ka Ikepili o ke koko platelets e hooholo coagulation kiko'î. Noʻonoʻo i ka maʻamau lehulehu o 180-320 tausani no mililika me.

Inā e hoʻonuiʻia platelets, alaila, he mea thrombocytosis. Oia kekahi ano e hōʻike i ka maʻi maʻi o ka infectious ano, hikoko, koko maʻi. Thrombocytosis hiki i ho okumu ana o ke koko clots i loko o nā ipu. Inā e hoʻonuiʻia platelets, he mea hiki i ke kino o dehydrated. Oia kekahi ano hiki ke triggered ma ka luaʻi, lawa ponoʻole loliʻai ana, noho kāna hana.

I ka lehulehu o platelets i loko o ke koko e oko i ka manawa o ka makahiki a me ka lā. Ua hakumakuma o ka halepaahao maʻiʻo hiki ke malama i ka menstrual wā a hāpai keiki. Pinepine platelets mahuahua ma hope o physical exertion.

Thrombocytosis ke hana i loko o nā mākua a me nā keiki. Mahuahua ka platelet lehulehu hiki e iniiaiie paha kiʻekiʻe.

Children thrombocytosis hookupaa hope loa o congenital abnormalities.

Initially nui ae platelets, nō kāu i eritremii, maʻi myeloid leukemia a me nā maʻi koko. Mahuahua o ka lehulehu o ke koko aeee ua pili me ka hoʻonui o ka papa o ka precursor (megakaryocytes). Kēia kaʻina He ano o malignant hou '.

Secondary thrombocytosis ia akulla 'i loko o ka maʻi i kupu mai ma hoonuiia? Iecaianoaaiiuo o thrombopoietin (polypeptide hōmona).

Platelets hiki e mahuahua ma ka ulcerative colitis, pulmonary tuberculosis, rheumatoid articular lesions ano extrapulmonary tuberculosis, amyloidosis, osteomyelitis, ake cirrhosis a me nā maʻi hoʻoʻino pathologies. Thrombocytosis ia lŘlŘ ma ke kāʻei kua o ka hooulu ana o malignant hikoko, hemorrhages, ma hope o kekahi mau hanau mā.