Ka lāʻau "Ursodez" - olelo ao no ka hoʻohana. Papa "Ursodez": analogs a me nā hōʻike manaʻo

Uluwehi O "Ursodez" - hepatoprotective lāʻau. Ua he choleretic medicament, hypolipidemic, holeliticheskoe hana, inā paʻa hypocholesterolemic a me ka immunomodulating kanawai negligible. ʻeleu 'Oponopono - ursodeoxycholicʻakika. Ka lāʻau 'ʻAʻohe laʻau heluna palapala "huaale". "Ursodez" ua hua mai i loko o ka palapala o capsules.

ha awinaʻano papa hana

Kaʻeleu lāʻau waiwai i ka hiki i ka e hoohui i loko o kaʻili lahilahi o hepatocytes, stabilizing kona 'ole. E like me ka hopena, e hoomalu ana i ke keena, mai pīhoihoi ihola ko lākou aʻe, i ka ha awina o ka bileʻakika paʻakai. Ka pākōlea hopena o ka lāʻau hoike pela ua hakumakuma he cytotoxic kanawai. E kū'ē i ke kāʻei kua o ka cholestasis haʻalele no Ca2 + e kaukaʻi protease Alpha-hauma¯na exocytosis. O ia hoʻi, "Ursodez" (hoʻohana palapala noi Hōʻike ia) nui ho'ēmi i kā ka meaʻawahia bile nāʻakika (deoxycholic, lithocholic, chenodeoxycholic a me kekahi poe e ae) ma ke kiekie nā hoʻohui like i loko o nā mea maʻi me pathologies ma maʻi ake pele.

I ka loaa ana ka lapaʻauʻia ia emi ma ka naʻokoko hoʻololi kemikala a me ka secretion, inhibition o kona omo i loko o ka naʻau liʻiliʻi. Manawa a hiki i keia, e emi ka saturation o ka bile me keia hui. Ka makaukau i ka hiki i ka competitively emi absorbability o lipophilic nāʻakika i loko o ka naʻau liʻiliʻi, mahuahua ko lakou holo fractionated ma luna o ke kumu o ka enterohepatic holo. Ka lapaʻauʻia stimulates ka excretion oʻawahia nāʻakika, mahuahua hooholo ia.

Keʻano papa hana o ka hana ana i ka lāʻau 'ua i ka nānā' ana ma luna loiloi 'nonpolar bile nāʻakika. No ka mea, o keiaʻawahia hui micelles. O ia hoʻi, intensifies ma ka biliary'ōnaehana, ka solubility o ka naʻokoko, stabilize? Iecaianoaaiiuo a me secretion o ka bile. Ka lāʻau no hoi ho'ēmi i kā kona lithogenicity, maoli ka lehulehu o nāʻakika, pela me ka hoonaukiuki aku i mahuahua ma ka hope o ka pancreatic a me ka gastric secretion.

I ka loaa ana o ka capsules ua piha a hapa noho male 'ana o nā pōhaku. Ma ka hoemi i ka bile naʻokoko saturation hoʻokāʻoi mobilization o nā pōhaku. Immunomodulatory ha awina ua hōʻike ma muli o ia i ke keiki ma ka lakou mau naoh ma ke akepaʻa. Ke k ho'ēmi i kā ka hōʻike o ka helu o ke histocompatibility antigens. Ke medicament ka lawe i ka hopena ma luna o ka iliwai o T-lymphocytes, hoemiia ka helu o eosinophils.

Pharmacokinetics ano

Omo o ka lāʻau "Ursodez" (ke hoʻohana i ke aʻo Hōʻike kēia) i loko o ka uuku liʻiliʻi hana ma kekahi kaʻina hana o ka OE maholahune. Extracted me kahi o 90% o ka hana ke keʻena. Ma ka ileum ka waiwai a ua kemuʻeleu amo. I ka lani kiekie loa maʻiʻo o kaʻeleu ke keʻena kīnā ka hola hoʻokahi hola. Ka hui i ka kiʻekiʻe pakeneka o ka paa kumuʻiʻo - 99%. Ursodeoxycholicʻakika mea hiki ke komo iloko o ke keiki.

Ka pākōlea hopenaʻoi loa o ka lāʻau hilinaʻi nui ma luna o ka lehulehu o ka hana 'Oponopono i loko o ka bile. At regular kahua hoʻonohonohoʻana loaa keia bileʻakika i ka iniiaiie lāʻau lapaʻau. ursodeoxycholicʻakika lehulehu mea ma kahi o 48%.

Ka hui Ua metabolized, ka mea hele ma ke akepaʻa keena. E like me ka hopena o ka hana a me ka glycine taurine conjugates. Ka palaho huahana e pee i loko o bile. Ka mea o 50-70% loaa ai 'excreted i loko o ka faeces. A uuku ka nui o ka lāʻau ua kaʻi aku i loko o ka AeXIeAaOIePEAaI. Aia ka mea, ua Wāwahi ma ka hana o ka koʻohune (7-dehydroxylation).

Lithocholicʻakika, a ua hanaʻia ma kēia kaʻina, ua hookauwa aku oia ia ia i ka hapa omo o ka naʻau liʻiliʻi nui, akā, hele sulfation i loko o ke ake, a excreted me sulfolitoholiltaurinovogo a sulfolitoholilglitsinovogo conjugate.

hoike

Medicine "Ursodez" paipai like me ka symptomatic Inc no iniiaiie biliary cirrhosis me na hoailona decompensation. E hōʻike i ka mea e hoike mai i ka meakino a me ka meaʻuʻuku naʻokoko na pohaku, a me kaʻeleu gallbladder. Prescribers me biliary reflux gastritis.

Contraindications

O ia hoʻi, "Ursodez" aʻo ma ka palapala noi, aole ia i ae i ka mākaʻikaʻi ina ka hoʻomanawanui rentgenpolozhitelnyh (ka lehulehu kiʻekiʻe o Ca2 +) gallstones intolerance medicament eiiiiiaiou. Contraindications nā cirrhosis i ka anu u decompensation hōʻike kāna hana o na pancreas, hakuʻala. Paipai lāʻau no ka poʻe me ka 'ole-functioning ka laau awaawa, bladder, huʻi hoʻoʻino pathologies o kona ano, e like me na naau oʻu maʻi a me ka bile leki uea. Mai i koi 'ia ka lapaʻauʻia i ka hapai a me ka hanai nou. O ia hoʻi, contraindicated no nā mākua a me nā keiki he pāʻumi emi o 34 kg.

ʻaoʻao waiwai

Ma kekahi mau hihia, hoʻomōhala hua'ōlelo i makemake 'ole ana e lawe i ka lāʻau, "Ursodez". Na Ke Kumu no ka i olelo aku o ka manawa kūpono o ka nausea, diarrhea, ka luaʻi. I ka lepo'āpana hana e hiki e hana calcified gallstones. Amplification ake transaminase haʻawina, abdominalʻeha, allergic reactions (me urticaria) i kekahi undesirable hopena, inu "Ursodez".

E hoike hōʻike maikaʻi tolerability. Ke kumuhana Ke i ke kauka i ka kuhikuhiʻaoʻao 'ole i olelo lealea. Ma kekahi mau hihia, i hana maikaʻiʻole o biliary cirrhosis malama transient decompensation. E like me ka rula, keia kŰia wale pilikia ma hope o discontinuation o ka lāʻau.

Uluwehi O "Ursodez". Price. i ke aʻo

Au makemake e lawe i ke ahiahi. Na kela la i keia laʻau heluna no ka mea hoʻoheheʻeʻia nā pōhaku - ka awelika o ka 10 mg / kg. No ka mea he pāʻumi mai i ka 60 kg ka mea, hoʻopili like 2nd capsules no lā i kg- 3-ka m 81, 100 kg - 4 hou 100 - 5. Duration - mai ka eono mahina a hiki i 12 mahina. Ma hope o mea hoʻoheheʻeʻia i ka pohaku, e pale aku i ke kahua o ka hou paipaiʻai ana no kekahi mau mahina.

Lapaʻau biliary cirrhosis lawe mai ma ka mahele lāʻau o ka 250 mg / lā. Duration o ka papa - 10-14 lā. i ka eono mahina. Ma kekahi mau hihia, ua mahuahua ka lōʻihi like 'ole o ka Inc i mau makahiki. E like me ka symptomatic lapaʻau medicament lawelawe 10-15 mg / lā. A hiki i ka nuipa a hiki i 34 kg i aʻo aku ma ka mea o ka wehe 'palapala. Ke kumu o ka lāʻau i loko o capsules - mai hoʻokahi haneri rubles.

Ua hana ka mea, 'o ia hoʻi "Ursodez" counterparts?

Ai 'i pihaʻi me na iaʻeleu waiwai, hua mai la i hala loa o ka hailona. I waena o lākou e pono ke kuai, e hōʻike i na mea e like "Ursodoksa", "Ursol". Kekahi o ka loa hanohano o ka lāʻau "Ursosan". Nāʻikepili no ka hoʻohanaʻana i ka lāʻau o kekahi nui. Ma kekahi, ka mea, ua lawelawe ia ma cystic fibrosis ake skleroziluyuschem cholangitis maʻi type.

He nui nā mea maʻi i hoihoi i ka mea maikaʻi hoʻomākaukau "Ursodez" a me "Ursosan". Ua pono e olelo mai la i ke kauka Nāna e koho i kekahi a me ka mea 'ē aʻe paha i kulike ai me ke ano, papa o pathology a me ka hoʻomanawanui tolerated ka waiʻona. I maʻi o ke akepaa, o ka gallbladder ua i kaena paipai naʻu. Ma mua o ka lawe i kekahi ka lapaʻauʻiaʻoe pono hookolokolo a me ka kūkā me ka hoʻomalu.

Ka mālamaʻana i ka laulā o ka iapaau ana e halihaliia oia iwaho o kela mea keia 6 mahina. Ma keia pili ka mea, ua häʻawi mai i ka papa ultrasound a me ka X-Ray hookolokolo ana i ka makahiki mua o ka nohoʻana. Inā ma ka eono mahina o ka noho male 'ana o nā pōhaku i: aole e hiki mua, e hoʻoneʻe' ia paha ka hoomau ana o ka papa impractical ma muli o ka inefficiency.

hou ike

E hōʻoia i ka holomua noho male 'ana o ka pohaku ka mea i pono i nā pōhaku he wale naʻokoko, akā, i ko lākou nui, aole ia i oi aku mamua o 15 a me 20 millimeters. I ka Ia manawa piha me ka laau awaawa, bladder e e ole aku ma mua o ka hapalua o, a me ka biliary'āpana e noho ma kona kuleana pili i loa.

Ma ka hihia o ka mākaʻikaʻi hooloihiia lapaʻau, oi ma mua o ka malama, ka mea i pono, e lawe mai i ka biochemical mea o loko no ke kālailaiʻana ha awina o transaminases ma ke akepaʻa. A eia hoi, ka mea e mana i ka lehulehu o ka bilirubin a me nā hui. ua oki ka lawe "Ursodez" mea e ana ka malama ana kiʻekiʻe hana. Reviews o na poe akamai, nae, e maikaʻi e pili ana i ka laulā o ka lāʻau.

ka hopena

Inā ole hopena hiki ke hāʻawi i kekahi medicament 'ole lapaʻau ka hoʻolālā loa hooponopono hou. Ma mua o ka hoʻohana 'ana i ka huina hoonui e e kama'āina i ka annotation.