'O Protein ka mea nui i loko o ka ho'ohui'ana i ka plasma toto

'A'ole hiki ke ho'onui'ia ka nui o ke koko. Ho'opiha nui kēia wai i nā hana nui o nā'ōpoki a me nā mea a me ka ho'opau'ana i nā huahana momona o ka hanu. Ma muli o ke koko e hiki ai i kēlā me kēia pūkana o ke kino ke ola.

'O ka koko'oi aku ka hapalua o ka plasma. 'O ka'ōma'oma'a he wai i loko o nā pūpū koko - ua hana lākou i kahi o ka hapa'umi o ka plasma. I ka haku mele 'ana o ke koko wai koko ka loa like - e'amino nāʻakika a me peptides, bilirubin, creatine, a me na mea he nui' ē aʻe inclusions. Eia kekahi,'o ka ho'ohui'ia o ka plasma toto e ho'opili'ia nā proteins - kekahi o nā mea nui loa.

Ma muli o kona'ano, ua māhele'ia nā protein i loko o nā hui - albumins, fibrinogen, globulins a me prothrombin. 'O lākou a pau he hapa o ka plasma toto, i ka lawelawe'ana i nā hana like'ole. Wai koko koko oihana i mea nui lehulehu, ka mea, ua pono no ka transfusion ma ka hihia o keʻoki kino. Ma nā'ano he nui, he plasma ka mea e kōkua i ke kanaka e pono ai ka ho'ohehe'e'ana.

'O ka mea nui loa i waena o nā protein a pau he albumins. Ka mea, ua nui loa ka paakiki ole (ka mea uuku hakakino nuipa a pau na kumu mua), no laila ia mea oluolu e lawe aku, a hui pu iho la me na kumu mua. Ho'okumu'ia nā hua'ōlelo i loko o ke ake. 'O ka'elua o ka pū'ulu nui o nā protein he globulins, i hana'ia e ke ake. Aia ka nui o ka plasma i loko o ka fibrinogen - he'ehā wale nō pākēka wale nō, akā na'e, he mea nui loa no nā hanana palekana he nui. A he'u'uku loa i loko o ke koko ka prothrombin.

'O nā māmā e ho'opili i ka plasma toto e hana i nā'oihana'ē a'e. Ma muli o ka loa'a'ana o ka wai ma waena o nā mea a me nā moku, e mau ana ka'ōpala wai, ua ho'olako'ia nā pūnaewele i nā mea'ai a ua "ho'oma'ema'e'ia" mai nā hua hana i hana'ia a'a'ole pono no ka mea ola. Eia kekahi, nā lālā i hana i ka hana ho'omalu.

Albumin malama i ka osmotic puʻe o ke koko. 'O kēia ke'ano o lākou ke kuleana no ka ho'oikaika pololei'ana o ke kahe koko i kēlā me kēia wahi o ke kino. Inā ka hapa o ke koko albumin hina, ka mea hiki ke alakai i ka wehe 'ana o ka wai a me ke kahua o ka edema (he vivid laʻana o ua hakumakuma ka nui o ka albumin - i ka lua o ka hapalua o ka hāpai keiki preeclampsia). 'O kekahi hana nui o nā albumins'o ka lawe'ana i nā mea like'ole. Ho'okomo nā huahelu i nā mea'ai a me nā toxins i ho'opili'ia e ke kino o ke ake.

Globulins pili kēia kuleana no ka mea e hoʻonele o ke kino, agglutination (agglutination hiki o erythrocytes i, a pela ka manao o lakou koko pae).

Prothrombin ma ka hui pu ana, me ka fibrinogen haawi mai i ka ana o ke koko (viscosity), i ka oi loa nui, no ka mea, ka mea kiekie loa ka make ana i loko o ke kia-Soviet aina mea ku pono i ka mea'ōnaehana mānowai koko maʻi. 'O ka ho'ohui'ana i ka plasma o ke koko ma nā'ano he nui e pili ana i ka hiki o nā kī'aha koko a me ka pu'uwai i ka ho'okahe maika'i o ke koko ma loko o ke kino. 'O ia ka prothrombin e ho'oponopono i ka viscosity, a no laila e pili ana i ka hiki'ana o nā moku e ho'ololi i ke koko ma o ke kino.

Fibrinogen - heʻeleu aku i komo i loko o ka clotting kaʻina. Ma muli o ke fibrinogen ua ho'ohui'ia nā filaments o fibrin, a he'ano thrombus-kāpili. Me ka kahe e hāmama ana,'o ka hana ia o ke fibrinogen e kōkua ai i ke koko a me ka hana i kahi thrombus a me ka'eha (inā'o ka'eha ma luna o ka honua). 'O kēia hiki'ana o ke koko i ka ho'oikaika'ia'ana e ho'opakele i ke kino mai ke kaumaha o nā koko. Eia na'e, ua loa'a kekahi po'e i kahi ma'i e like me hemophilia - ka hiki'ole ke lilo i ke koko. Inā he kino ka hana a ka Xromromome i loko o ka'ike, hiki i kēia ke alaka'i i ka nui'ole o nā kaula fibrin, a no laila, hiki'ole ke hana'ia he thrombus. 'O kēlā hana hewa e hō'ike hou ana i ka nui o ka hana i ka fibrinogen, no ka mea, e hopohopo mau ka hemophilia i ka make mai ke koko i ka mea li'ili'i loa.

'O ke'ano o ka plasma toto ke'ano like'ole, akā,'o ia ka proteins e pā'ani i ka hana nui loa. He mea nui i ke kanaka ke hana i nā ho'ā'o ma'amau e ho'oholo ai i ka nui o nā kumu protein, a inā pono, e hana i nā mea e ho'okumu i ka homeostasis i ke koko.