Ka lāʻau 'kalipuna pantothenate': 'ano a me ka hoʻohana' ana i ka lapaau

Pantothenicʻakika (laʻau heluna palapala - ka lāʻau "pōhaku pantothenate") me i loko o ka pae o ka wikamina B. kēia oily, opticallyʻeleu wai, hoomaikai wailana i loko o ka wai, ua hooholo koke a pipili ma lalo o ka hana o ka wela, nāʻakika a me alkalis.

Pantothenicʻakika ua loaʻa i loko oʻai, a ua synthesized ma intestinal microflora (Escherichia). Ma hope o omo mea komo i ke koko, a ua lawe i nā mea a pau nā loko a me nā'aʻaʻa, ua waihoia ma ke akepaʻa, kekahi hapa ma ka myocardium, hakuʻala a me skeletal Muscle. Ma ke kino, kaʻoi loaʻakika me nā polokina, a me ka hapa o ka CoA (coenzyme A) pili. hālāwai hope huahana o ka lāʻau "kalipuna pantothenate" excreted ma ka mimi a me feces. Ua pono e mai la oia i ka helu o ke koho pantothenicʻakika mea mauʻoi aku ma mua i ka i komo i ke kino a me ka ai. Kēia mea ma muli o ia kona mea koʻohune hoʻololi kemikala.

Pantothenicʻakika mea he ke keʻena o CoA, a he ekolu māhele: ke koena tiolamina, pantothenicʻakika, 3-phospho-5adenozin-5-diphosphate. CoA mea he ki hehee ai i loko o pūnao, e komo ia i loko o ka functioning o ka Krebs kalapona ma o ka liluwelo hoʻololi kemikala a me ka'okesaside o carbohydrates, lipids, glucosamine ho okumu, acetylcholine, hippuricʻakika, porphyrins, etc.

Uluwehi O "pōhaku pantothenate" - iki yellowish a keʻokeʻo ka pauka me ka ho'āʻoʻana awaawa, odorless, wailana i loko o ka wai. Koʻana koko pāʻoihana o thermally i ka pilina paʻa, akā, hoʻomaka koke hoʻohiolo nō ia i ka wā paku ole ia iʻakika a me ka mekala 'åkilikai. Ka mea lāʻau lapaʻau e hoʻomākaukau ai ua hua mai la i na papa, ka pauka a me nā pāʻoihana ma hue.

Kona pharmacological hana makaukau "pōhaku pantothenate" hōʻike ma hope o pantothenicʻakika iho i loko o coenzyme A, i hoakaka Hoʻokolohua-'okesaside, momomaʻakika hoʻololi kemikala, oxidative decarboxylation, a me ka hoʻololi 'ana i pyruvicʻakika a me ketoglutaric acetyl. Ua kōkua i ke omo o ka monakō koko i loko o ka naʻau liʻiliʻi, maoli i ka nui o ka glycogen ma ke akepaa, normalizes ka hormonal kūlana o ka meaola, o ka oi aku i hāpai keiki.

At deficiency o pantothenicʻakika i loko o ke kino, ua inhibited hōmona papa pituitary, adrenal gland a me ka pancreas. Ke adrenal glands ho'ēmi i kā ka nui o steroid hormones, a i pigmentation o ka lauoho a me ka ili. Metabolic kāna hana hoʻonāukiukiʻana mai o dermatitis, ili depigmentation. Degenerative loli mālama i loko o ka adrenal glands a me ko mākou hopohopo'aʻaʻa. Ka mea, hiki no hoi e uhaʻiʻia Hawaii ōhumu, worsen hakuʻala maʻi, naau, a me ka naʻau liʻiliʻi'ōpū. Ke iniiaiie kumu o ka wikamina ia wā, ua lawa dala o keia wikamina i ka ai, na naau oʻu maʻi, a me ka hooloihi ae i pono o antibiotics (sulfonamides, antibiotics).

I ka papa kuhikuhiE lapaʻau na hoailona o ka nele o pantothenicʻakika i loko o ke kino - kaumaha, luhi, luhi, Kanikani'āʻula, headaches a me Muscle eha, nausea, diarrhea, flushing o ka ili ana, duodenal ulcer. At deficiency o ka wikamina hoemi immunological ia'ku o ka meaola. Kū'ē i kēia kāʻei kua, loa pinepine eia naehana maʻi.

loa pinepine, kauka i koi 'ia ka lāʻau "kalipuna pantothenate" no ka rula o metabolic keʻano o ka hanaʻana. ʻae ma la medicament polyneuritis, paresthesia, neuralgia, bronchitis, eczema, dermatitis,'ā, trophic ulcers, hāpai keiki toxicosis, tuberculosis, hypothyroidism, pancreatitis, gastroduodenitis, etc. Medicine "kalipuna pantothenate" pono-tolerated ma ke kino. No ka mea, enteral i dyspeptic symptoms, ma ka parenteral (intramuscular ka pahu kui) - soreness.

Oversupply o ke kalipuna (hypercalcemia) ke'ākoʻakoʻa ma muli o ka dysfunction o ka endocrine glands (parathyroid gland). Hypercalcemia ua kakau ia ma ka kūpuna. hypercalcemia ke Kalinika ke hoike i mau nawaliwali, lilo o ka ikaika loa ka makemake, ka mea, i kekahi manawa mālama cramps a me constipation.