"Mesakol": aʻo no ka hoʻohana 'ana, maoli counterparts

Ulcerative colitis a Crohn ka maʻi e malama i loko o nā mea maʻi nei he pohihihi keia. Akā, manaʻo huhū i kēia, ua nui na ai 'i i manao e hana i kēia mau maʻi. Kekahi o ia mea "Mesakol". Na Ke Kumu no ka hoʻohana 'ana, palapala, i kou manaʻo, a me ka waiwai e lilo ana o na dala e e hōʻike mai iā ia ma lalo nei.

I ka haku mele 'ana, i ke kalaʻana aku palapala,'ōpala a me ka hōʻikeʻano

Uluwehi O "Mesakol", hōʻike manaʻo o ka mea e loa kekahi henua ano, hele i kuai me he ulaula-mea eleele o na papa io. Ka mea, e enteric-lole komoʻuʻuku nona, a i ka hoʻopoepoe a me ka lenticular ano.

I ka papa kuhikuhiE waiwai o ka mea paahana protrudes mesalazine (5-ʻAsa). Ma waho aʻeo ia mea i ka lāʻau nā nā eiiiiiaiou e like me ka palaoa pia, kalipuna posapahate dihydrate, talc maloko, microcrystalline kelulose, titanium'okesaside, hypromellose 2208, ka silica i colloid, povidone K90, paʻakai carboxymethyl pia, ka copolymerʻakika methacrylic a me ka meto methacrylate, ula hao'okesaside, macrogol 6000 a me ka dibutyl phthalate.

Papa "Mesakol" ua hanaʻia i loko o Aluminum holehole mai ai a me ka pepa he huihui 'pakahi.

pharmacology

Aole anei oe i ike ia mea he lāʻau "Mesakol"? Na Ke Kumu no ka hana hōʻike 'ana i kēia Anati-hoʻoʻino Agena, ua IIeEeAIEUIeXAIIUE i ka hopena o ka i loko o ka naʻau liʻiliʻi. Kēia waiwai o ka medicament aie i kona waiwai, e inhibit i ka hoʻololi kemikala o leukotrienes a me prostaglandins, a me ka neutrophil lipoxygenase.

Mākou E hoi e hoailona oukou i ka noʻonoʻo lāʻau 'aʻole hoʻi Polenekia, phagocytosis a me degranulation o neutrophils, e like me immunoglobulin secretion ma lymphocytes.

He aha nā waiwai i ka laau "Mesakol", ke kumukuai o ka i ua hōʻike ma lalo nei? Mesalazine mea antimicrobial hana ku e kekahi cocci a me Escherichia coli (i loko o ka AeXIeAaOIePEAaI).

Pharmacokinetics

He aha nō ka hoʻomaopop 'ana i kinetic kiko'î papa "Mesakol"? Na Ke Kumu no ka hoʻohana hākālia nō ia ma hope o aaieieno? Mesalazine ua hookuu mai ka iwi hope ma kahi o 115-165 minuke, a ma hope o 170-230 minuke papa hoike mai.

Manawa e noonoo lāʻau ho film kapa komo iā ia ma luna o 60-80% ua hoʻokuʻuʻia i loko o ka naʻau liʻiliʻi nui, a me 15-30% - i loko o ka uuku liʻiliʻi. Ma keia hihia i kaʻeleu waiwai kīnā ka systemic holo wale i loko o ka nui o ka 10% o ka mahele lāʻau. Mesalazine lehulehu i loko o ka wai koko ka loa haʻahaʻa.

Palapala o ka hana 'Oponopono i ka wai koko nā polokina o 43%. Noʻonoʻo i ka lāʻau a me kona metabolites i loko o ka umauma o ka waiu.

Pūnao mesalazine hana i loko o ka naʻau liʻiliʻi a me ka akepaʻa. Kēia produces N-acetyl-5-aminosalicylicʻakika.

Ka hapa-ola o 60-120 minuke (ke kaumaha ma muli o ka mahele lāʻau). E hōʻike 'ia ka lapaʻauʻia nā konāhua, a ma ka naʻau liʻiliʻi.

Nāʻikepili e loaa ka lapaʻauʻia

I Hawaii maʻi o ka lāʻau "Mesakol"? Reviews o kauka hōʻike i kēia mea paahanaʻano ka pono hoike mai ai ia ia iho i loko o Crohn ka maʻi a me ka ulcerative colitis.

It E e hoʻomaopopo i ka noʻonoʻo medicament ua hoʻohana 'ole wale no ka lapaau ana i ka hua maʻi akā, no hoi no ka Kāohiʻana o exacerbations.

Contraindications i ka lapaʻauʻia

Prescribers "Mesakol" i paipai:

• ma peptic ulcer o ka digestive oihana;
• koko maʻi;
• loaʻaʻa puʻuwai insufficiency;
• hemorrhagic diathesis;
• i kamaliʻi;
• loa hepatic hoʻopilikia;
• hypersensitivity i na nā mea hoʻohui o ka lāʻau;
• ka nele o ka monakō koko-6-posapahate dehydrogenase.

Special mālama i kēia hoʻomanaʻo hoʻohana ma o ka mehana a me ka lōpūʻaʻa puʻuwai maʻi oolea, e like me lōpū a me ka mehana hepatic insufficiency.

Papa "Mesakol": kauoha no ka hoʻohana

O na dala ia hōʻike waha 'pono ma hope o kaʻai.

Ma exacerbation o ka maʻi ka mea, ua lawelawe i loko o ka nui o 400-800 mg (a laila, 1-2 papa),ʻekolu manawa i ka lā. Ke Inc ua lawe mai no 9-12 pule.

No ka mea Kāohiʻana o exacerbations o ka lāʻau i ka 400 mg,ʻekolu manawa i ka lā. Nā papa i nuiʻana i loko o ka palapala o, inu maʻamau ka wai.

Pehea, e haawi aku na keiki i ka lāʻau "Mesakol"? Kukui, microclysters a me ka wehe 'ia' - ma keia palapala ua hōʻike i ka lāʻau a hiki i keiki kao.

Adverse reactions

Eia naʻe, lalau iho la ka lapaʻauʻia manaoia loa pinepine ke kumu noʻaoʻao ole. O nā nā kēia:

• pericarditis, tachycardia, cardiac conduction kāna hana, hypertension, umauma eha, hypotension, palpitations, pokole o ka hanu;
• nausea, ua hoʻemi ikaika loa ka makemake, ka luaʻi, mahuahua ma ka akepaa transaminases, heartburn, stomatitis, diarrhea, hepatitis, abdominalʻeha, pancreatitis, maloo waha;
• oliguria, proteinuria, crystalluria, hematuria, nephrotic maʻi pale, anuria;
• pōniuniu, headache, hallucinations, tinnitus, Kanikani'āʻula, polyneuropathy, convulsions, tremor, kaumaha;
• eosinophilia, thrombocytopenia, anaemia (haemolytic, aplastic, a megaloblastic), agranulocytosis, anaemia, hypoprothrombinemia;
• oligospermia, impotence;
• nawaliwali, photosensitivity, mumps, hoemi i ka? iecaianoaaiiie o ka waimaka loli, lupus-e like maʻi pale, alopecia;
• ili rashes, dermatitis, pruritus, bronchospasm, erythema.

Symptoms o overdose

Symptoms overdose noonoo mea nei iluna o na kumu e like me nausea, gastralgia, ka luaʻi, sleepiness a me ka nawaliwali. E hoʻopau ia ua hoakakaia gastric lavage, laxatives a me symptomatic Inc.

Hoʻokaulike me nā huahana

Uluwehi O "Mesakol" ho'ēmi i kā ke kanawai o "spironolactone" "Furosemide", "rifampicin" a me sulfonamides. Ua hoi hoʻokāʻoi aʻe ana i hypoglycemic hopena o sulfonylurea nā mea loaʻa, i ka kaʻawahia o methotrexate a me corticosteroids ulzerogennosti.

It E e kaulana no hoi ia i ka lāʻau 'aʻole hoʻi i ke omo o ka cyanocobalamin, a me maoli i ke kanawai o uricosuric Luna (' o ia hoʻi, blockers omo secretion) a me ka hoʻokāʻoi aʻe ana i ka hopena o anticoagulants.

kekahi koi

• Diarrhea 'ia i lapaʻau "Mesakolom"' aʻole e mau ia i ka lokomaikaiia i kaʻaoʻao kanawai o ka lapaʻauʻia. e ia he ano e he hoailona o nń ku maʻi.
• Iloko o ke? Eaia, pono e lawe i ka mea paahana mau mai, he pono ole ke koko a me ka mimi ho'āʻo ma.
• Inā ka mahele lāʻau i lilo, i kēia 'E e ia i kekahi'ē aʻe manawa.
• Iloko o ka iapaau ana me keia ka lapaʻauʻia, a me ka hoʻomanawanui ka mimi waimaka loli i ke 'ia nā pōpō i loko o ka melemele-ʻalani waihoʻoluʻu.

Uluwehi O "Mesakol": counterparts a me ka waiwai e lilo aku

E puku i ka mea i olelo lapaau hiki e ma ka mea e like me "salazopiridazina", "5-Asa", "Tidokol" "Asacol", "Samezil", "salofalk", "Mesalazine", "Salozinal", "pentasil".

Pehea ka nui o nā ka "Mesakol" papa? Ke kumukuai o keia k mea 600-680 rubles (50 na papa).

consumer hōʻike manaʻo

E hoomanawanui i haʻalele i ka "Mesakol" hoomalolo ka loa hui nāʻana. Kekahi o ia mau mea hōʻike i ka lāʻau kuleʻa Hawaii intestinal maʻi. 'Ē aʻe hoʻopaʻapaʻa ua mau huaale ua lapuwale. Pela, ua hiki paa manao nei makou, "Mesakol" loaʻa kekahi mau 'ole ma kekahi nā mea maʻi.

I ka papa kuhikuhiE drawback o keia ka lapaʻauʻia o ka nui helu o contraindications a me adverse reactions.