Carcinoid maʻi pale: symptoms,ʻike, a me ka lapaʻau

Lapaʻau 'ikepili helu hōʻike i ka helu o ka maʻi' aʻai, ua steadily ala. Ona e nā haumāna mai increasingly kakauia i kela makahiki. Kēia mea o nā mea a pau i ka oi pihoihoi iho la ia, a ke kumu lapaau, e hoʻomaka kāohi hana iwaena o ka heluna kanaka ma ka mea e malama i kona wahiʻano pākīkē expansive ulu.

Carcinoid maʻi pale: He aha ka mea?

Carcinoid - keia mea o ka loa e like me kaʻeho no na keena o ka neuroendocrine nenoaiu. Mau keena e ia i loko o kekahi hui, a me nā'aʻaʻa. Lākou mau papa kuhikuhiE papa - e hoʻomōhala loa kaila nā polokina. About kanawalu pakeneka o nā mea a pau carcinoids i aia i loko o ka gastrointestinal'āpana, ma kekona wahi e na maʻiʻaʻai. Nui aku kākaʻikahi, elima wale pakeneka o ka hihia, e loaʻa hikoko i loko o nā nā loko a me nā'aʻaʻa.

Carcinoid maʻi pale a carcinoidʻeho hiki ole ke kaawale mai kekahi i kekahi, e like me ka maʻi pale - he lākou o nā symptoms eʻikea au i loko o ka kāʻei kua o ka ulu a me ka mama no hoi o ka malignancy. Ma hope o nā mea a pau, i ke kino reacts i noho i loko o ka hormones koko pee ma kaʻeho. na naau oʻu carcinoids paha e "aa", oa 'aʻole e hoike ia ia iho a hiki i ka manawa a loaʻa nō metastases, a me ka maʻi, aole ia e hele i loko o ka maʻi ke kahua.

kumu

Noiʻi nō i lawa ka 'ike i maopopo ke kumu hoʻomōhala carcinoid maʻi pale a me carcinoidʻeho. Epekema ke ieoaeunoai hypotheses e pili ana i maʻi etiology, akā, pau 'aelike i ka mea i ka'ōnaehana paleʻea nenoaiu ma kekahi wahi pohaku eʻike mutated keenaʻo ko'ōnaehana (ka inoa pōkole o nā palapala mua o ka hua'ōlelo "Amene," ", hoʻokomo", "kaʻaluna", "decarboxylation" ).

A hookahi maʻi 'aʻai aeea ma ka mea e mai o ka mea nui i piha hou ka ulu ana e paka hormones a me ka hoʻololi' ana i ka hoʻopiʻi i kou pono a pau o ka biochemical keʻano o ka hanaʻana i loko o ke kanaka kino.

pathogenesis

Pehea hiki hoʻomōhala carcinoid maʻi pale? He aha ka mea a pehea e pale ia? Ua haawiia i neuroendocrine aeee aia ma ke kino, a me ka lapaʻau hoike ana mai o kaʻeho kokoke, aole i pau i ke kaʻina hana, kauka mea i hiki ke.

Ma kekahi wahi i loko o ka halepaahao o "ka hoʻokō 'ole" DNA i ua loaʻa hou kekahi incorrectly mau, e hana me ka poino apana nahaha. Ua hele aku ai i ka hoʻohuikau 'o ka halepaahao hana a me kona kipi i ke ku e. Inā i ke kino, ua ola, ka'ōnaehana paleʻea nenoaia, e pane koke i ka mutation, a no ka pakele ana i ka hana kupua mau ukana. Inā keia 'ole e hana, alaila, o ka halepaahao, e hoonui, e ho okumu ana miliona o kope, a olalo i palahalaha ae ma ka kino toxins a me hormones.

kauka pinepine ole e kuhikuhi i ka wahi o kaʻeho, hoʻowahāwahā symptomatic carcinoid maʻi pale.

Carcinoma o ke akemāmā

Wale umi pakeneka o na hihia i loko o ka naehana'ōnaehana i hoʻoikaika i haanou ana, a, nolaila, carcinoid maʻi pale. Me na hoailona hoi ma ka akemāmā e e ole-kekahi, a me kekahi manawa,ʻaʻole i nā mea a pau. O ke kumu ho i ka kŘpa a uuku ka nui o ka hikoko, a me ka wa e kaawale aku o metastasis. E hoomanawanui i imi kōkua mai ka nui mai, a, e like me ka rula,ʻaʻole he oncologist, a me ka mea mua i ke kino. He hiki i unsuccessfully e hana bronchiolitis, asthma a naehana ka hoʻokō 'ole, a me ka manao alo o ka maʻi' aʻai kaʻina.

Symptoms ma keia hihia mea atypical:

• palpitations, palpitations;
• dyspepsia;
• e manao ana i ka wela a me ka naku ana o ke koko a hiki i ka hoaka o ka hapalua o ke kino;
• cough, pokole o ka hanu;
• bronchospasm.

Me kēia 'ia paha o kāna hana hiki apuepue ke kēia carcinoid. No depletion, drastic kaumaha lilo, ka ho'ēmiʻana o ka e hoʻonele, luhi a me nā symptoms ano o ka maʻi 'aʻai kaʻina.

uuku na naau oʻuʻeho

Ma ka liʻiliʻi liʻiliʻi iki aku pinepine ia ma mua i loko o ka akemāmā, kaʻeho ua palapala a me kona hele pū ana carcinoid maʻi pale. Na hoailona o ka mea i loa hiki ole no ia. Pinepine, ua ole-i ho'ākāka 'abdominal eha wale. O ke kumu ho i ka poe uuku a nui o kaʻeho. I kekahi manawa ia mea,ʻaʻole hiki ke loaʻa i ka hana. Education ua pinepine ike e wale ma radiological ninaninau.

Wale ma kahi o umi pakeneka o nā hikoko o ka uuku liʻiliʻi o ka etiology o ka aoao o ka carcinoid maʻi pale. No ka mea kauka, i kēia 'o ia hoʻi i ka kaʻina ua lilo malignant a ua palahalaha ae ma ke akepaʻa. Mau hikoko hiki i obturation o na lumen o ka naʻau liʻiliʻi, a me ka hopena, intestinal iaʻi. Ke hoomanawanui hele mai i ka haukapila me ka hana-me na eha,, nausea, ka luaʻi a me kāna hana o ka noho. A me ke kumu o keia kulana, e ike wale ma ka pae'ōnaehana papa.

Iaʻi hiki e kena ae la ia e alaʻeho nui a me ka torsion liʻiliʻi ma muli o kaʻike manaʻo o ka fibrosis a me ka li nui o ka mucousʻili lahilahi. I kekahi manawa, na scars i ko koko a hiki i ka naʻau i kahi, i hiki aku ai i necrosis a me ka peritonitis. I kekahi o kēia mau kūlana mea he ola-hooweliweli ana ia, a i alakai i ka make ana o ka hoʻomanawanui.

Aʻeho no ka i paiiaʻi

Hikoko o ka i paiiaʻi na - he ke nānā hanana i loko iho. Iwaena o lakou carcinoids kūlana 'he hanohano o kona maka mua wahi, akā, Ane hiki i carcinoid maʻi pale. Hoailona o ko lākou'āina hiki ole no ia. E like me ka rula, ka mea, o ka mea, ua ulu a pathologists ma hope o appendectomy. Haanou ana i ka nui ka emi o kekahi kenimika, a hoi loa "noho malie". Hiki wale mai nō i ka hope o ka wehe 'ana o kaʻeho no ka i paiiaʻi akaka ma kekahi'ē aʻe wahi, mailuilu haalele.

Akā, inā i kaʻeho i 'akomi i loko o nā kenimika ma ka nui, a me ka nui, oe e e wary o metastasis i loko o ka kūloko lymph aka wahi, a kūkākūkā o kaʻeho aeee i loko o nā nā loko. Ano o appendectomy i loko o ia ka hihia hiki ole Makuakane a me nā mea a pau i ka loiloi, a e i ia,ʻo oncologists e hoʻomaka i ka hulina lapaau.

Rectal carcinoid hikoko

Kekahi IIeEeAIEUAA, ma i aneane i hoʻohikiʻia carcinoid maʻi pale. No na hoailona o kaʻeho, a accidentally loaʻa iloko o PalekanaEND_LINK ke kaʻina hana e like me colonoscopy paha sigmoidoscopy.

Ka pahiki o malignancy (malignancy), a me ka helehelena o ka loihi mai metastases hilinaʻi nui ma luna o ka nui o kaʻeho. Inā ka mea, ua oi aku ia mamua o ka anawaena o mau kenimika, o ka pilikia o ka complications mea e pili ana i kanawalu pakeneka. Inā kaʻeho, aole ia i hoopaa i ai i kekahi kenimika ma ka anawaena, e hiki eʻoiaʻiʻo i kanaiwakumamawalu ko-ewalu pakeneka, aohe mea nana e metastasis.

No laila, ke hoʻokokoke i ka iapaau ana i loko o kēia mau hihia mea okoa. A uukuʻeho ua wehe 'ana ka hoʻokele waiwai resection o ka AeXIeAaOIePEAaI, a ina he mau hoailona o ka malignancy, ka mea makemake e hoʻopaʻi ana no ka AeXIeAaOIePEAaI holoʻokoʻa, e like me chemotherapy.

gastric carcinoid

He ekolu ano carcinoid hikoko o ka opu, e kauoha ana carcinoid maʻi pale. Nā hiʻona o keʻano mua o ka hikoko.

• uuku Ana (i ka 1 knm);
• benign papa.

Hiki aku o kaʻeho paakiki ka wā o nā kaʻina hana ka hopuʻia ka'ōpū holoʻokoʻa. Ka mea, i pili me ka pertsinoznoy anaemia a maʻi gastritis i loko o ka hoʻomanawanui. Lapaʻau no ia hikoko mea e loaa somatostatin inhibition o? Iecaianoaaiiuo o gastrin a gastrectomy.

I ka lua o kaʻano o kaʻeho ulu lohi, kākaʻikahi lilo cancerous. Ka mea, e prevalent i loko o nā mea maʻi me ka aaiaoe kāna hana e like me mau endocrine neoplasia. Kahaha kou naau i wale i ka'ōpū, akā, me ka pineal gland, thyroid gland, pancreas.

Ke kolu o kaʻano o kaʻeho - he nui hikoko e ulu ana i loko o ke ola i ke'ōpū. Ka mea, e malignant, komo hohonu i loko o ke kino paia, a hoomakaukau i mau metastases. Hiki i perforation a me ka kahe ana ke koko.

Hikoko o ka AeXIeAaOIePEAaI

Ka nui liʻiliʻi - o ka wahi, kahi o ka loa pinepine diagnosed carcinoid maʻi pale a me carcinoidʻeho. Photo mucosa i ka hookolokolo ana o ka na naau oʻu Hoʻohana hōʻike i ke alo o ka nui (elima mau kenimika a oi) hikoko. Ka mea, metastasize i ka 'āina' lymph aka wahi , a mea kokoke manawa malignant.

Oncologists i loko o ia mau manawa e aʻo aku ai iā ia'ano'ēʻoki kino me ka adjuvant a me ka neoadjuvant chemotherapy e hoʻokō i ka maikaʻi kanawai. Akā, ola prognosis no kēia mau hoʻomanawanui iki mai nei nō noho lakou malaila.

Carcinoid maʻi pale: Symptoms, kiʻi

I ka hoike ana mai o ka carcinoid maʻi pale hilinaʻi nui ma luna o ka waiwai i extractedʻeho. Kēia hiki e serotonin, bradykinin, histamine a chromogranin A. ka loa typical na hoailona o ka maʻi i:

• Redness o ka maka, a me ka hoaka o ke kino. Ua lŘlŘ ma aneane pau loa nā mea maʻi. Pu ma ka kūloko mahuahua ma ka ana wela. Ho'āhewa wale ana spontaneously, ka mea hiki ke triggered ma ka waiʻona, stress a me ka hoʻokō '. Ma keia hihia, he mea tachycardia, puʻe kulu.
• Hāʻule pohō wale o ka noho. ¾ makana i loko o nā mea maʻi. Nō kāu, keia ia lŘlŘ ma muli o ka hookaawale ana i ka mucousʻili lahilahi o ka digestive'āpana, kāna hana o na naau oʻu iaʻi.
• Hoʻohuikau o ka naau i hoʻomaopop 'ana i loko o ka hapalua o nā mea maʻi. Carcinoid maʻi pale paipai 'ia ka ho okumu ana o ka naau kiwikā stenosis a me ke kumu no cardiac ole.
• Maʻi o loko o ka maʻiʻaʻai i aie i ka spasm o ka bronchi.
• Abdominalʻeha ua pili i ka muli o metastases ma ke akepaʻa, intestinal iaʻi aʻeho kaua i loko o nā nā loko.

Carcinoid ulia - he ana i ua wehewehe aku ma kahi nihinihi hiki kulu ma ka puʻe iʻoki kino. Nolaila, e hoomanawanui i lawelawe somatostatin i like manipulations.

lapaʻau '

Ua mea hiki, e huai ae carcinoid maʻi pale? Hoailona, kiʻi, disparate lapaʻau o symptoms, aole ia e haawi i ka maopopo lapaʻau kiʻi, i hiki hopena. Loa pinepine kaʻeho - he accidental loaʻa i ka surgeon a radiologist. I mea e hōʻoia i ka alo o ka hikoko, ia mea e pono ke hana i kekahi biopsy o ka hoʻohuli ai i nā wahi a nana i ka'aʻaʻa.

Hiki nō ke hoʻohana 'ia i ka hoao ana, e huai ae ke kiekie pae o hormones, akā, i kēia mau' ikepili i e hōʻike i loohia i kekahi, a me ke kauka mai e pohihihi mai i o ia kona mea e hana ai. Ka loa kekahi ho'āʻo o ka helu ana o 5-hydroxyindoleaceticʻakika. Inā ua hoomahuahua ia kona 'ilikai, ka pahiki o carcinoid -ʻaneʻane 90%.

chemotherapy

Anei ka mea, e pono e hana chemotherapy-carcinoid maʻi pale? Hoailona, Hawaii photo mucosa ma EGD biopsy 'āina' lymph aka wahi a hormonal loli ke haawi aku i ke kauka i ka manaʻo o nā complications i i kena ae la i loko o ka hoʻomanawanui i ke alo o kaʻeho. Inā ke kēla mea noho lakou malaila no ka mea hoʻomanawanui a hiki ina ka wehe 'ana o kaʻeho, i ka poe akamai i kūkā e akoakoa ai i ka chemotherapy.

Loa pinepine, kauka hoʻohana cytotoxic Luna e inhibit i ka ulu a me ka hoʻomohala o hikoko. Akā, no ka mea, o ka helu nui o kaʻaoʻao hopena o keia iaoia ua paipai wale i ka hihia o ka pilikia. Ma waho kona laulā - 40 wale%.

symptomatic lapaʻau

Aia i ke koikoi manaʻo i i ike ma ke kāʻei kua o pathologies e like me carcinoid maʻi pale, carcinoidʻeho. ahupapa a Symptoms e e pili loa ana i ke 'ano o ka hōmona e hookuu aku oia iʻeho. Inā keia mea serotonin, ke hoʻomanawanui mea kuhikuhi antidepressants. Inā i ka papa kuhikuhiE "aggressor" ka histamine, alaila, e hele mai i ka mua blockers histamine receptors ma Inc.

kemikala analogues o somatostatin i ua loaʻa, hoemi symptoms ma aneane 90%. Ka mea, inhibit ka? Iecaianoaaiiie o kekahi mau hormones mea i kuleana no lākou paʻa wahi i loko o ka iapaau ana o keia maʻi.

operative Inc

An ka hoʻokahuli i loko o ka iapaau ana mea e wehe i kaʻeho, mai ke kino, a me ka huli resected metastases, akepaʻa artery ligation.

Ma ka buke o keʻoki kino e loli ai i ka wahi a me ka nui o ka hikoko, i ke alo a kaawale o metastases. Loa pinepine, surgeons wehe i ka maÿi hapa o ke kino, a me ka pūʻolo helu o nā 'āina' lymph aka wahi. E like me ka rula, he nui e hoola i kanaka mai carcinoid ka wa pau ole. I nui kou hihia, ka wā curative lapaʻau mea i hiki, ka hoʻomanawanui ua kono e pana aku au i embolization o ka hepatic artery, e wehe i ka symptoms o ka maʻi.

Outlook

He aha e manaʻo ai nā mea maʻi diagnosed me carcinoid maʻi pale a me carcinoidʻeho? Flushing, palpitations a me bouts o breathlessness, hoʻoneʻe 'ia paha, e noho ana me ia a hiki i ka hope o ke ola, akā, e lilo emi hai ma hope lapaau.

Medicine, eia nā hihia ma ka hoʻomanawanuiʻana ma hope oʻoki kino ola ana oi ma mua o umi makahiki, a me symptomatic Inc. Akā, kā lākou awelike ola kīkoʻo kona mea e pili ana 5-10 makahiki. Ka meaʻino prognosis iʻeho aia i loko o ka akemāmā, a me ka maikai - i loko o ka i paiiaʻi.