Nā kumu o Lassa mai kuni maʻiʻaʻai. Symptoms, lapaau a me kaʻike,

Lassa wela o ka maʻi pili i ka pae ana o hemorrhagic mea hoʻomaʻi nā mea palahēhē. E like me ka hopena, ka mea e loli ai ka puʻupaʻa, ke akepaʻa ua luku, ulu nui kuni. I ka maʻi ua wehewehe aku ma ka huʻi capillary toxicosis, ka wā hui me ka ili poino ma na moku a me kā lākou permeability, piʻi pū ili honua dramatically. Loa ke ola-hooweliweli maʻi, make ia lŘlŘ i loko o 40% o ka hihia. Kela a me keia makahiki ka hapa miliona kanaka e ae, mai Lassa kuni. I ka maʻi i loko o ia lŘlŘ elua pule, mea pakahi aku la ia paakiki e lawe i kuni nā wāhine i loko o ka lua o ka hapalua o ka hāpai keiki, ma keia hihia, o ka make i kela mea ma kahi o 80%.

Geographic mau mea o ka hoolaha aku

I ka makahiki 1969, Nigerianʻepekema hooholo wela i waena o nā kupa o ke kaona o Lassa maʻi i paku ole ia i ka noiʻi a me ka la ia i kahu malama. O ka mea mua elima hoopii, ekolu i alakai aku ai i ka make ana o nā mea maʻi. Microbiologists makahiki ma hope kuhikuhi i ka causative hope. Lassa wela i keia manawa uhi i ka'āina i loko o West Africa, e like me :. Guinea, Mali, Nigeria, Senegal, a me kekahi poe e ae mai i lag i hope ma ka olelo o ka epidemiological paepae a me ka Central māhele o kaʻApelika Waena'āinapuniʻole. I kekahi manawa, na lesions ana i loko oʻEulopa aina, kaʻIseraʻela, USA, Japan, ma ka mea hoʻomaʻi pathogen ua hoolilo holo poe kanaka.

Description wela pathogen

Ke causative Agena o Lassa kuni mea he 'eleleʻohana o ka mea hoʻomaʻi genomic RNA, i mea ole DNA like me ka aaiaoe ike encoded i loko o kekahi' ole mau RNA kaulahao. Ke 'ole coincides me ka' ole o ka mea hoʻomaʻi Bolivian a me ka Argentinean kuni pathogen choriomeningitis. Mea hoʻomaʻi virion anawaena o ka pono 80-160 HI, ka mea, ua puni iho la ia ma ka hoʻopoepoe lipid wahī nona ka ili ua uhiʻia me ka olona,. Keia hookolokolo ana ma lalo o ka microscope hōʻike mea hoʻomaʻi (particles) i loko o umi ribosomes ho i ke kaumaha o ke olonā i granules.

Aie i ke alo o na (particles), like mānoanoa ko, mea hoʻomaʻi Arenavirus loaa ka inoa o ka ohana Arenaviridae (i loko o Roma arenaceus Kû ke one). Over kaʻumi makahiki i hala iho neiʻepekema i 'akomi i 4 subgroups, i mea Lassa kuni, a me ka māhele ma kekahi mau wahi o Africa. Mea hoʻomaʻi ia'ku i ka loli ma ka puni mea i kona hiki i ka hana, e noho ma ka hui 'ana me ke koko, a me ke kino huna ia i lilo ai no ka lōʻihi manawa. I ka ho'ēmi i kona hope ua hoʻohana 'chloroform a me Etera.

Sources a me hawkers mea hoʻomaʻi

Nā moku halihali mokulele o ka mea hoʻomaʻi i manaoia multimammate iole o kaʻApelika Waena'āinapuniʻole, me ka manao e Mastomys natalensis. Epidemiological hoʻopōʻino mau mea i ka helu o ka iho mailoko o kanaka, he 14-18% o ka huina heluna kanaka o kaʻiole, ka rodent mea he mea hoʻomaʻi iho mailoko o ia no ke ola, i kekahi manawa, me ka symptoms o ka maʻi. Ke kumu o ka maʻiʻaʻai mea no hoi he maʻi ke kanaka, a pau fluids a i infectious i 'ē aʻe kino.

Lassa wela maʻiʻaʻai kumu komo i loko o EYI o ka maʻiʻaʻai ma ka lewa me ke kinowai droplets ka wā puʻu, kiheʻana, ha. Ka maʻiʻaʻai ua loaʻa i loko o faeces a me ka mimi o ka iole, i hiki kiʻi i loko o ka ai a me ka kanaka ili. Maʻiʻaʻai i loko o ua hoʻohaumiaʻia wahi ia lŘlŘ ka wā ana lewa atomized huna uuku holoholona lepo, hoʻohana o ka ona mau, mai ka wai kahi mea hoʻohaumiaʻia e nā mea hoʻomaʻi a insufficiently moa, ai iole mau hoopauia ai.

Ma waena o lakou iho rodents hoʻolele i ka mea hoʻomaʻi ma luna o ka leo, inu, e ai ana,? Aneii. Mai ka hoomanawanui iho mailoko me ka okoa kanaka Hoʻokaʻaʻike kāu kiʻina hana a me nā kiʻie hōʻikeʻike. Hapai makuahine ae i ka mea hoʻomaʻi kino a hiki i ka bebe. infectious maʻi? aaieou limahana kaʻohiʻana i mai ma ka lapaau ana o ke koko a me kaʻoki lāʻau lapaʻau 'uao, autopsies, e lawelawe ana nā mea maʻi me ka loa catarrhal symptoms. Ma ke koko o nā mea maʻi ma hope o ka maʻi, Lassa kuni na lau nā mea'aʻaʻa, a hoomau anei i ai i 7 makahiki, i hiki ke obnaruzht ma ka keʻena hoʻokolohua noiʻi.

Ka epidemiological kulana home 'ole

I ka maʻi ua manaoia e ia he mea nui mea hoʻomaʻi na mai kuni. Ka poe i kamepiula loa nō i ka poʻe e noho lā ma ke komohana hapa o Africa. Maʻiʻaʻai mea like paha i loko o nā ke kauhale, a ma ke kulanakauhale, ma muli o ia i ka heluna nui o ka iole multimammate. More ma mua o ka hapalua o na mea ona.

Ka hanana no e hoʻonele i ka maʻi recurring uuku? Anoee, akā, i na hihia o ka maʻiʻaʻai kekahi manawa i hoʻomaka ai, a me ka hoopuka moakaka lapaau a me ka Kāohiʻana o Lassa wela, aole ia i koi nui ho'āʻo pono, i ka maʻi i loko o ka ia maʻiʻaʻai. Ma aneane nā māhele o Africa maʻiʻaʻai ascertained a pau makahiki a pau, akā, me ka nui helu o outbreaks i loko o ke anu wa pono, ka wā mau poʻe a pau o nāʻiole hoʻoneʻe pili ana i ka hale kanaka.

Hihia o ka mea hoʻomaʻi hoʻoneʻe i ke aupuni i loko o ka Europa'āinapuniʻole e lawe wahi, akā, no ka pale ka hohola mea malalo iho i ke kanana 'helu mahina ma luna o ka' āina me ka unahiʻole a pau mai kuni. Kanaka o nā sexes e like ma kamepiula o ka maʻiʻaʻai. Ka loa, pili mea hoʻomaʻi hohola ma wahi me ka ilihune sanitation, ilihune densely nń wahi pa.

Ke pathogenesis o ka maʻi

Ke mucousʻili lahilahi o ke kanaka kino o ka'īpuka no ka maʻiʻaʻaiʻai ana. Mea hoʻomaʻi no ka hooholo ana o ka incubation au, ua IIeEeAIEUIeXAIIUE ma ka lymph aka wahi ma ka hopena ke kahua huʻi febrile wā hoʻomaka me ka laha ana o (particles) ma luna o nā mea a pau kino nenoai. Ke keena o ka mea nui nā loko, i loaʻa i ka mea hoʻomaʻi, lawe ma luna o nā Hekikai o cytotoxic lymphocytes, he mea Lassa kuni. Symptoms a me ka lapaau ana i ka maʻi no ka hana hoihoi i waena o hoʻomalu. Ma ka papa o ka ulu i ka maʻi necrosis o ke ake , a konāhua, spleen a me ka luku ana o ka naau Muscle.

Ke oolea o ka maʻi hilinaʻi nui ma luna o ka e hoʻonele o ka meaola, no laila, ona e hoʻoholo ma mua aʻe 'aeea pane. Inā he febrile wā maʻi ho okumu ana o nā mea'aʻaʻa, e hoʻopau nā mea hoʻomaʻi kaulia ana, a ua hoopanee no - ka mea, hoike mai ai ia ia iho, e like me Lassa kuni. Photo o ka hoʻomanawanui ua hōʻike ma lalo nei.

Symptoms o ka maʻi Lassa

Ke incubation au mau mai ka hebedoma kekahi i ekolu, a laila, hoʻomaka ka huʻi pae o ka maʻi pu ma ka ano symptoms:

• feverish moku'āina hoʻomaka me ka hōʻemi iki mahuahua ma ke kino ana wela;
• hoike mai ai ia malaise, he manao o ka nawaliwali;
• he myalgia,ʻeha ma ka puu wā moni 'ia;
• mau maka i loli ana i conjunctivitis;
• me ka mahuahua ana ma ke kino mahana e ole listen nawaliwali;
• a kiola loaʻeha i loko o ka hope, abdomen, umauma;
• kekahi manawa, he mea nausea, diarrhea, convulsions;
• me ka puʻu i ka luaʻi;
• meaʻehaʻeha pokole o ka pilikia makapō a puni.

ka ninaninau ana i ke ahonui

Mau makana iloko o ka nana nani o ka ai a me ka maka, umauma wahi, eia hemorrhagic 'ole ma kekahi wahi, palpation kaulana he nui mahuahua ma ka lymph aka wahi. laryngeal ninaninau hōʻike ulcers, mucosal wehewehe aku ma ka helehelena keʻokeʻo kahi lilelile i, harbingers a mahope ulcers o ka mea e hāʻawi mai Lassa kuni. Symptoms o ka hoike ana o ka naau i ike ia i loko o hāmauʻana nanahe, bradycardia, a emi paha o loko o ke koko,. Me ka hou papa o ka maʻi ulu myocarditis, bradycardia a me tachycardia auou caiaiai.

Ana o kēia maʻi lawe ma luna o kaʻili o ka hoʻomanawanui lehulehu hemorrhages, ma ka hou iā ia, ma laila nā hanaʻino wale, papules, roseola, kekahi manawa i ka poʻe noʻonoʻoʻole ma luna o ka 'ano ka nani a hoike ana o Waimānalo. Ka naau ua ho'ākea, i ka hoʻomanawanui i hopohopo i pokole o ka hanu, cough, maʻi i loko o ka maʻiʻaʻai wai a maloo ke ano. O na wahi o ka peritoneum ua ikeia eha, kalaka i loko o ka abdomen, diarrhea. Ma ka like o ke hoonee aku i akepaʻa. Ko mākou hopohopo'ōnaehana kāna hana i hoike mai ai ia ia iho, Lassa kuni. Epidemiology memo hihia o ka lilo o ka ike paka i, lohe poho, tinnitus, aia no he piha a hapa balding poo.

Keʻena hoʻokolohua haʻawina hoike aku i ke koko leukopenia, laila leukocytosis, pela 'oni iki i ka haʻalele wbc, wehewehe aku ma ka mahuahua platelet helu, a ua hoʻemi prothrombin, mahuahua ESR i 50-80 mm o / h. emi koko clotting, mahuahua prothrombin manawa ia lŘlŘ. Hakuʻala ole hana ia iho, ikeia kiʻekiʻe ka maʻiʻo o ka urea i loko o ke koko, i ke ao e hōʻike ana i ke ahonui o ka mimi a me ka proteinuria cylindruria. Mimi kekahi mau leukocytes, erythrocytes, kumuʻiʻo impurities granular nā paukūʻolokaʻa.

No ka Lassa wela pili ia i ka mea nuiʻano maʻi mea ua lawe mai i kēia mea hoʻomaʻi epidemiological mōʻaukala, hōʻike i nā preconditions no ka hoike ana o ka mai, no ka mea o hoomanawanui i ka noho ana i loko o ka ua hoʻohaumiaʻia wahi. E like me ka noiʻi hoʻopololeiʻia ana X-Ray, FDSG, ultrasound, MRI poino nā loko, a kino nenoai. Ma ka wehewehena o ka maʻi, e hoomanawanui i imi i ke aʻo o ka pulmonologist, cardiologist, neurologist, gastroenterologist.

Loa ka holo ana a me ka complications

I 37-52% o ka hihia, me ka oolea o ka maʻi hiki aku ai i ka loa lesions o na maʻiʻaʻai (pneumonia e loli iki oolea), naau (myocarditis), ake (cirrhosis), hakuʻala (ole). Loa edema pleural mau mea o ke kino hoike mai ai ia Lassa kuni. Epidemiology, lapaʻau hiʻona, Kāohi 'aʻole e mau loa ana me hāʻawi maikaʻi Time] a i curative' ole. More ma mua o ka hapalua o na hihia wńnana i ka hoomanawanui i ka make ma hope o nā pule o ka hoouka kaua. Pono mai nei no 3 pule, a laila, hoʻomaka e emi i ka mahana. Loaa Ua kali, hou-hōʻike nō ia o symptoms mai manawa i ka manawa, aia no na relapses.

Differentiationʻike, a me nā maʻi

E like me na mea he nui o na symptoms hoike ana o ka maʻi i like i ka hemorrhagic na mai kuni o nā ano. Typhus, dengue kuni, lenalena kuni, Kyasanur nahele maʻi, West Nile, Chikungunya, Malaria koaʻe ke, heʻulaʻula kuni, meningitis kohu Lassa kuni. Marburg, Ebola mea kekahi ma luna o ka pā i ka hailonaʻana ma ka pono ole, a e e hoʻokoe 'ia mai nā kēia maʻi.

Malaria mea i 'ano like me ka symptoms o Lassa mea i ka wā nā maʻi he mea he kiʻekiʻe kino wela nā hoailona, headache, yellowing o ka ili. Ke koena unuhi waiho i loko o ka mea i malaria ua ole wehewehe aku ma ka helehelena o necrotic ulcers i loko o ka puu, a me ka nui ulu i loko o ka lymph aka wahi, kākaʻikahi hoʻomōhala haemorrhagic maʻi pale. Eia hou kekahi, malaria ua wehewehe aku ma ka haikea ili, excessive sweating a me ka haoʻa hoike ana o ke kuni, Patchy wikiwiki.

Hemorrhagic wela me kaʻaʻa puʻuwai maʻi pale ua wehewehe aku ma na symptoms o Lassa maʻi, hoikeia ma ka eha o ke poo a me ka Muscle cramps, sclerite, conjunctivitis, oliguria. Akā, ka mea, aole i i HFRS i loko o kānaka ikaika ka luaʻi, ulcerative pharyngitis a me ka diarrhea. Haʻalele maʻi Lassa pele, mai ka lā mua o ka maʻi ia lŘlŘ maloo waha, ka makewai a me ka loa nawaliwali o nāʻiʻo.

No ka leptospirosis ano pili symptoms me ke kuni, headache, myalgia, conjunctivitis, scleritis, oliguria. Akā, me ka nele o ka leptospirosis me necrotic ulcers i loko o ka wahaʻano distinguishes ia mai Lassa kuni. Inā leptospirosis ua ole puʻu, diarrhea, retching, ua i 'akomi i ole pahu eha ma ka keʻena hoʻokolohua haʻawina leukopenia, bradycardia. Muli o kona kulana kekahi mau hoailona i Lassa kuni. Photos loli ana e ka maʻi ua hōʻike ma lalo nei.

Marburg wela mea he huʻi mea hoʻomaʻi ala me ka loa symptoms, me symptoms like ia Lassa maʻi. A kiʻekiʻeʻano o ka make,? Acaeoey o ke kuni, hemorrhagic maʻi pale, hanahana loa lesions o ka na nā loko, a me ka Central ko mākou hopohopo nenoaiu. Ke kumu o ka maʻiʻaʻai ia,ʻaʻole pono hookupaaia, ka mea, ua manaoio aku i ka mea hoʻomaʻi ua pū i hiki i kānaka ma ka uliuli Keko droplet a ea paha, a ma ka hui 'ana me ka holoholona.

pākōlea ki ina hana like

A pau e hoomanawanui i mahuʻi mua o ka iho mailoko o, e noho malalo iho o ke muli o hospitalization i loko o nā keʻena lāʻau lapaʻau kūikawā. A hiki i ka maʻiʻo o ka hoʻomanawanui i ka iapaau ana malama i ka ikaika? Eia o ka hoʻokaʻawale 'ole kekahi' aʻe '. Hoakaka ia papamoe moe kulana, e haawe hoʻokoe ', lapaʻau ua nona ma ke kāpaeʻana i nā symptoms o ka maʻi ana. Ma ka mua pule o ka manao o lakou kumu, a me ka hana ana o Lassa kuni i loko o ka wahi mua o ka hoʻohana 'ana o ka convalescent wai koko. Kēia mea mana ma ka hoʻomaka o ka maʻi wale, mai ka pono o ka lapaʻauʻia no ka hooloihi ae i ke kuni, i ka hoʻonāukiukiʻana i loko o kekahi mau hihia, mea hōʻemi o ka mai, a me ka hooulu ana o complications.

he complication o ka maʻi ua ia me antibiotics a me corticosteroids ikaika. Ma kēia 'inikua mea lāʻau lapaʻau hana etiotropic hoʻomohala hou ai' a me vaccines. Haʻi'ōlelo i koe i keia la i ka hoʻohana 'ana o ai' i loko o ka iapaau ana o virazole, ribamidil, ribavirin. Ka mea, ua lawe ia ma ka loiloi mua ke kahua o ka maʻi hōʻike waha, ma ka dala 1000ed no ka lā. ? Eaia e mai ana no 10 lā. Intravenously lawelawe lawa ka lapaʻauʻia no 4 lā, i kokua, e hoʻoikaika i ka papa o ka mea maʻi, a emi i ka make kōmi.

Kāohiʻana o ka maʻi

Nui me ka lilo nui o ke ola mai no kekahi Lassa kuni. Maʻi Kāohi mea o ka nui nui i loko o ka epidemiological kamepiula mau mea. E pale aku i ka anal o kanaka noho o ka mea hoʻomaʻi, paʻa komo i ka mea multimammate iole a me nā laha 'o rodents. IeAUPIIe, IAa IO, ka ai a me ka inu wai pūnāwai o ka hou huahana akahele sheltering i mea e hoʻopau i ka ingress o ka mimi a me ka hana lepo o rodents. Like prophylaxis etched wahi a iole ukali ia e kuni kupapaʻu.

ua uku nui kāohi pono i ka hoʻomaikaʻi i ka hae o ke ola o ka lāhui 'ōiwiʻApelika Waena heluna, hoʻoikaika i ka mea e like ai o ka ai no ka muli o ka lawa'ōnaehana paleʻea palekana o ka meaola. E paa ana ia i mea kamaʻilio a me nā haʻi'ōlelo e hōʻoi 'i ka moʻomeheu - ohua pae, wehewehe i ka pono no kaʻaeʻana i ola mau hae kanaka no kēlā me kēia kanaka.

Kauka a me nā 'inikua limahana maʻiʻaʻai nā keʻena lāʻau lapaʻau i koiia e hōʻoia i ka mea e pono ai' ano o ka 'auamo prophylaxis, e like me Loan a ea paha no ka hoʻomanawanui malama. E aʻo, a hoouna aku la i ka kūloko epidemiological kamepiula āpana kauka no ka pono a me ka maluhia hana o ke piʻoloke, a hōʻoia i Anati-'ōkuʻu? Eia.

Lawe mai nā hana i loko o ka outbreak o ke ahulau hanana

Kahua hoʻonohonohoʻana quarantine hana pono lawe wahi, ina ma kekahi wahi he mea Lassa kuni. e lawe Na Makuahine ana mai me ke kali ole koke. Ka mea, e nona ma e hoʻolālā i ka paakiki quarantine me ka piha hoʻokaʻawale o infectious nā mea maʻi i loko o ka pahu, i nā poʻe ke aoʻana o ka hoouka kaua ana o ke ahulau. All pili nā limahana, e mae wale pono Anati-maʻi costumes a me pilikino aiiay lako a pan.

He muli o hospitalization o ka poe hoʻohuoi nui 'ia hui' ana me maʻi, e aa ana me kekahi mea waiwai o ka mea a me ka hale 'ikamu Bolney a meʻia ke kanaka, i ka'a'āʻana i loko o ka crematorium o ka maʻi o ke kino, disinfection o ka pa a me ka home. Kanaka i hiki mai ai i wahi "maemae" o na wahi o ke ahulau, kaʻawale ma ka haukapilaʻo loko o ka hanana o ka mea iki e hoʻohuoiʻia o ka hanana o ka maʻi.

Ma ka hopena, ka mea e e hoʻomaopopo i ka make kuni emi ana o, ina pololei lawe mai, e hamama ai e lawe mai ae mālama 'ana ka hoʻokō ana, e emi i ka pilikia o ka maʻi,' eleu kanaka ua hoʻomaka 'ana.